Stereocontrol in Organic Synthesis Using Silicon Compounds

  • Ian Fleming
  • Dick Higgins
  • Achintya K. Sarkar
Chapter
Part of the NATO ASI Series book series (ASIC, volume 289)

Abstract

Stereocontrol based on the principle illustrated in 1 allows the 1,5 transfer of chiral information in some SE2″ reactions, as shown in Schemes 5 and 6, and, to some extent, the control of exocyclic double bond geometry, as shown in Schemes 15 and 16. The latter device is used in a highly stereocontrolled synthesis of the carbacyclin analogue 49.

Keywords

Chiral Centre Silyl Group Exocyclic Double Bond Dimethyl Acetylenedicarboxylate Bicyclic System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Ian Fleming
    • 1
  • Dick Higgins
    • 1
  • Achintya K. Sarkar
    • 1
  1. 1.University Chemical LaboratoryCambridgeEngland

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