• G. M. Woerlee
Part of the Developments in Critical Care Medicine and Anesthesiology book series (DCCA, volume 18)


Some of the causes of hyperkalemia of relevance to anaesthetic practice are listed below. There are of course many more possible causes, but the reader is referred to an excellent review by DeFronzo et al [1] for a more detailed discussion of these.


AMERICAN Heart Journal Plasma Potassium Neuromuscular Blocking Drug Sodium Polystyrene Sulfonate Plasma Potassium Concentration 
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  1. 1.
    DeFronzo, R.A., et a1.,(1982), Clinical disorders of hyperkalemia. ANNUAL REVIEW OF MEDICINE, 33, 521–554.PubMedCrossRefGoogle Scholar
  2. 2.
    Lim, M., et al.,(1981), Propranolol, exercise, and arterial plasma potassium. LANCET, 2, 591.PubMedCrossRefGoogle Scholar
  3. 3.
    Hassan, H., et al.,(1979), Hypercapnia and hyperkalemia. ANAESTHESIA, 34, 897–889.PubMedCrossRefGoogle Scholar
  4. 4.
    Fulop, M.,(1979), Serum potassium in lactic acidosis and ketoacidosis. NEW ENGLAND JOURNAL OF MEDICINE, 300, 1087–1089.PubMedCrossRefGoogle Scholar
  5. 5.
    Miller, R.D., et al.,(1972), Succinylcholine-induced hyperkalemia in patients with renal failure? ANESTHESIOLOGY, 36, 138–141.PubMedCrossRefGoogle Scholar
  6. 6.
    Kopriva, C., et al.,(1971), Serum potassium changes after succinylcholine in patients with acute massive muscle trauma. ANESTHESIOLOGY, 34, 246–249.PubMedCrossRefGoogle Scholar
  7. 7.
    Gronert, G.A., Theye, R.A.,(1975), Pathophysiology of hyperkalemia induced by succinylcholine. ANESTHESIOLOGY, 43, 89–99.PubMedCrossRefGoogle Scholar
  8. 8.
    Tobey, R.E., et al.,(1970), Paraplegia, succinylcholine and cardiac arrest. ANESTHESIOLOGY, 32, 359–364.PubMedCrossRefGoogle Scholar
  9. 9.
    Ballantyne, F., et al.,(1975), Cellular basis for reversal of hyperkalaemic electrocardiographic changes by sodium. AMERICAN JOURNAL OF PHYSIOLOGY, 229, 935–940.PubMedGoogle Scholar
  10. 10.
    Surawicz, B.,(1967), Relationship between electrocardiogram and electrolytes. AMERICAN HEART JOURNAL, 73, 814–834.PubMedCrossRefGoogle Scholar
  11. 11.
    Surawicz, B., et al.,(1967), Hemodynamic and electrocardiographic effects of hyperpotassemia. Differences in response to slow and rapid increases in concentration of plasma K. AMERICAN HEART JOURNAL, 73, 647–664.CrossRefGoogle Scholar
  12. 12.
    Cohen, H.C., et al.,(1971), The nature and type of arrhythmias in acute experimental hyperkalemia in the intact dog. AMERICAN HEART JOURNAL, 82, 777–785.PubMedCrossRefGoogle Scholar
  13. 13.
    Finch, C.A., et al.,(1946), Clinical syndrome of potassium intoxication. AMERICAN JOURNAL OF MEDICINE, 1, 337–352.PubMedCrossRefGoogle Scholar
  14. 14.
    Nugent, M., et al.,(1984), Verapamil worsens rate of development and hemodynamic effects of acute hyperkalemia in halothane anesthetized dogs: Effects of calcium therapy. ANESTHESIOLOGY, 60, 435–439.PubMedCrossRefGoogle Scholar
  15. 15.
    Leight, L., et al.,(1963), The effect of intravenous potassium on myocardial contractility and cardiac dynamics. AMERICAN JOURNAL OF CARDIOLOGY, 12, 686–691.PubMedCrossRefGoogle Scholar
  16. 16.
    Bradley, W.G.,(1969), Adymnamia episodica herediteria. Clinical, pathological and electrophysiological studies in an affected family. BRAIN, 92, 345–378.PubMedCrossRefGoogle Scholar
  17. 17.
    Troni, W., et al.,(1978), Electromyographic study on experimental hyperkalemia. I. Electrophysiological alterations. ACTA NEUROLOGICA (NAPOLI), 33, 381–389.Google Scholar
  18. 18.
    Troni, W., et al.,(1978), Electromyographic study on experimental hyperkalemia, II. Effects on neuromuscular transmission. ACTA NEUROLOGICA (NAPOLI), 33, 390–398.Google Scholar
  19. 19.
    Gage, P.W., Quastrel, D.M.J.,(1965),Dual effect of potassium on transmitter release. NATURE, 206, 625–626.PubMedCrossRefGoogle Scholar
  20. 20.
    Parsons, R.L., et al.,(1965),Presynaptic effects of potassium ion on the mammalian neuromuscular junction. NATURE, 208, 590–591.PubMedCrossRefGoogle Scholar
  21. 21.
    Troni, W., Luda, E.,(1978), Electromyographic study on experimental hyperkalemia. III. Motor deficits. ACTA NEUROLOGICA (NAPOLI), 33, 399–407.Google Scholar
  22. 22.
    Foldes, F.F., et al.,(1971), Studies of pancuronium in conscious and anesthetized man. ANESTHESIOLOGY, 35, 496–503.PubMedCrossRefGoogle Scholar
  23. 23.
    Miller, R.D., Roderick, L.L.,(1978), Diuretic induced hypokalemia, pancuronium neuromuscular blockade and its antagonism by neostigmine. BRITISH JOURNAL OF ANAESTHESIA, 50, 541–544.PubMedCrossRefGoogle Scholar
  24. 24.
    Waud, B.E., Waud, D.R.,(1980), Interaction of calcium and potassium with neuromuscular blocking agents. BRITISH JOURNAL OF ANAESTHESIA, 52, 863–865.PubMedCrossRefGoogle Scholar
  25. 25.
    Payne, J.P., et al.,(1980), Neuromuscular blockade by neostigmine in anaesthetized man. BRITISH JOURNAL OF ANAESTHESIA, 52, 69–75.PubMedCrossRefGoogle Scholar
  26. 26.
    Levinsky, N.G.,(1966), Management of emergencies. VI. Hyperkalemia. NEW ENGLAND JOURNAL OF MEDICINE, 274, 1076–1077.PubMedCrossRefGoogle Scholar
  27. 27.
    Dreyer, F.,(1982), Acetylcholine receptor. BRITISH JOURNAL OF ANAESTHESIA, 54, 115–130.PubMedCrossRefGoogle Scholar
  28. 28.
    Braun, H.A., et al.,(1955), The influence of hypocalcemia induced by sodium ethylenediamine tetraacetate on the toxicity of potassium. JOURNAL OF LABORATORY AND CLINICAL MEDICINE, 46, 544–548.PubMedGoogle Scholar
  29. 29.
    Winkler, A.W., et al.,(1939), Factors affecting the toxicity of potassium. AMERICAN JOURNAL OF PHYSIOLOGY, 127, 430–436.Google Scholar
  30. 30.
    Frankenhauser, B.,(1957), The effect of calcium on the myelinated nerve fibre. JOURNAL OF PHYSIOLOGY (London), 137, 245–260.Google Scholar
  31. 31.
    Frankenhauser, B., Hodgkin, A.L.,(1957), The action of calcium on the electrical properties of squid axons. JOURNAL OF PHYSIOLOGY (London), 137, 218–244.Google Scholar
  32. 32.
    Fraley, D.S., Adler, S.,(1977), Correction of hyperkalemia by bicarbonate despite constant blood pH. KIDNEY INTERNATIONAL, 12, 354–360.PubMedCrossRefGoogle Scholar
  33. 33.
    Villamil, M.F., et al.,(1975), Anion effects on cation movements duing correction of potassium depletion. AMERICAN JOURNAL OF PHYSIOLOGY, 229, 161–166.PubMedGoogle Scholar

Copyright information

© Kluwer Academic Publishers 1988

Authors and Affiliations

  • G. M. Woerlee
    • 1
  1. 1.Department of AnaesthesiaUniversity Hospital of LeidenThe Netherlands

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