Blood flow measurements using 3D distance-concentration functions derived from digital x-ray angiograms
We describe a method for measurement of velocity flow, absolute cross-sectional area and path length of identified arteries for high frame rate biplane x-ray angiograms. The system has been extensively validated with phantoms for vessel calibres from 3 to 6 mm and flow rates encompassing those expected “in-vivo”. Mean volume flow agreed with electromagnetic flow meter readings to within 9% and peak flow agreed to within 10% for velocity flow below 1 m/sec when measuring a 150 mm length of artery at a framing rate of 25 frames per sec. Path lengths of bent wire were measured with an error of less than 2%. We present initial results using these measures to study the haemodynamics of the circulation from the arch of the aorta to the circle of Willis.
KeywordsDigital Subtraction Angiography Vessel Segment Blood Flow Measurement Flow Waveform Epipolar Line
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