The Implication of pH on the Design of an Enzymatic Reactor for Penicillin Hydrolysis
In this paper penicillin acylase is used to exemplify the effect of pH on the design of enzymatic reactors. Simulation programs are used to describe the batch, continuous stirred tank, packed bed and recirculated reactors using a triple inhibition model for enzyme kinetics, an electrochemical model to describe the pH changes with conversion and an Arrhenius type equation to account for the pH effect on enzyme stability.
KeywordsBatch Reactor Continuous Stir Tank Reactor Penicillin Acylase Arrhenius Type Equation Recirculation Mode
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