Chromatographic Methods for Determination of Chlorophenols as Biomarkers of Exposure to Pesticides and Organochlorine Substances

  • Paulo de Morais
  • Teodor StoichevEmail author
  • Maria Clara Basto
  • Maria Teresa Vasconcelos
Conference paper
Part of the NATO Science for Peace and Security Series C: Environmental Security book series (NAPSC)


Chromatographic methods for chlorophenols (CPs) determination that can be applied to clinical (blood, urine) and breast milk samples are reviewed. Special emphasis is given to sample storage conditions and to the application of preconcentration techniques. Solid phase extraction, solid phase microextraction, stir-bar sorptive extraction, liquid phase microextraction and steam distillation methods are considered in view of the potential use of CPs as biomarkers of exposure to different pesticides.


Chlorophenols Chromatography Blood plasma Urine Breast milk 



Funds from CIIMAR (PesT-C/MAR/LA0015/2011) and the Foundation for Science and Technology (Portugal) are acknowledged for the fellowships awarded to P. de Morais (SFRH/BD/66492/2009) and T. Stoichev (SFRH/BPD/32700/2006) co-financed by POPH/FSE.


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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Paulo de Morais
    • 1
  • Teodor Stoichev
    • 2
    Email author
  • Maria Clara Basto
    • 1
  • Maria Teresa Vasconcelos
    • 2
  1. 1.CIMAR/CIIMAR, Centro Interdisciplinar de Investigação Marinha e Ambiental and Faculdade de CiênciasUniversidade do PortoPortoPortugal
  2. 2.CIMAR/CIIMAR, Centro Interdisciplinar de Investigação Marinha e AmbientaPortoPortugal

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