Principles of Solid-State Fermentation Engineering and Its Scale-Up

  • Hongzhang Chen


Industrial solid-state fermentation (SSF) is not widely used because of engineering difficulties and the lack of guided principles on the fermentation process and scale-up from the physics aspect and porous medium. From the nature of the biological processes, SSF can be featured as the continuous phase of the gas phase compared with the continuous phase of the liquid phase in submerged fermentation. It is important to recognize traditional SSF from the aspect of the gas-liquid-solid phase. In SSF, mass and heat transfer are crucial for understanding and applying this old technology. This chapter introduces the essence of SSF and its related influencing factors from the engineering aspect. It includes the essence of SSF, transfer principles, thermal physics phenomenon, and design and scale-up of bioreactors. The hope is to find novel means to solve the problems of mass and heat transfer in SSF and eventually achieve its industrialization.


Heat transfer Mass transfer Porous media Fermentation process Scale-up 


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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Hongzhang Chen
    • 1
  1. 1.Institute of Process Engineering, CASBeijingChina, People’s Republic

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