Using Genome-Enabled Technologies to Address Allergens in Seeds of Crop Plants: Legumes as a Case Study

  • Lena Y. C. Soo
  • Nicole E. Walczyk
  • Penelope M. C. Smith
Chapter

Abstract

In this chapter, we discuss how genome-enabled technologies have improved identification of legume seed allergens and are contributing to the development of hypoallergenic legume crops. We show how proteomic identification of allergens will be driven by the availability of plant genomes. The expression of the major allergens can be reduced or eliminated by gene silencing, mutation, or genome editing. The limitation of these technologies to agricultural performance and food quality, and the clinical consequences of modified food products are described.

Keywords

Legumes Seed allergens Food allergy Hypoallergenic Gene silencing Mutagenesis 

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Copyright information

© Springer Science+Business Media Dordrecht 2012

Authors and Affiliations

  • Lena Y. C. Soo
    • 1
  • Nicole E. Walczyk
    • 1
    • 2
  • Penelope M. C. Smith
    • 1
  1. 1.School of Biological SciencesUniversity of SydneySydneyAustralia
  2. 2.Department of Chemistry and Biomolecular SciencesMacquarie UniversityMacquarieAustralia

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