Extraneural Metastasis in Medulloblastoma

Chapter
First Online:
Part of the Tumors of the Central Nervous System book series (TCNS, volume 8)

Abstract

Extraneural metastasis in medulloblastoma is rare and occurs in 1–2% at initial diagnosis and up to 5–10% during a patient’s lifetime. The most common sites of extraneural spread are the bone, bone marrow and lymph nodes. The survival is generally thought to be poor, but recent studies have indicated that certain subsets of patients may have a better outcome. Adverse prognostic factors have been identified which include concurrent central nervous system involvement, presence of lung or liver metastasis, a time of interval of <18 months from initial diagnosis of medulloblastoma to development of extraneural metastasis and patient age <16 years at time of extraneural spread.

Keywords

Posterior Fossa Stereotactic Body Radiotherapy Intracranial Tumor Bone Marrow Involvement Boost Radiotherapy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media Dordrecht 2012

Authors and Affiliations

  1. 1.Weil-Cornell Medical College, Department of Radiation OncologyThe Methodist HospitalHoustonUSA

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