Non-equilibrium Air Plasma for Wound Bleeding Control
A low temperature non-equilibrium air plasma spray is tested as a blood coagulator. Emission spectroscopy of the plasma effluent indicates that it carries abundant reactive atomic oxygen (RAO), which can activate erythrocyte – platelet interactions to enhance blood coagulation for plug formation. Tests of the device for wound bleeding control were performed on pigs. Four types of wounds, straight cut and cross cut in the ham area, a hole in an ear saphenous vein, and a cut to an ear artery, were examined. The results showed that this plasma spray could effectively stop the bleeding and reduced the bleeding time considerably. Post-Operative observation of straight cut and cross cut wound healing was carried out. It was found that the plasma treatment had a positive impact on wound healing, in particular, of the cross cut wound; its healing time was shortened by a half.
KeywordsPlasma Spray Plasma Plume Tissue Oxygen Tension Plasma Treatment Time Dissociative Attachment
We are grateful to Alessandro Betti for fabricating the plasma spray device. This work was supported in part by a NYU-Poly seed Grant and in part by Adventix Technologies Inc.
- 1.Jevon P, Cooper L (2008) First aid. Part 5. First-aid treatment for severe bleeding. Nurs Times 104:26–7Google Scholar
- 12.Kuo SP (2010) Portable plasma sterilizer. US Patent US7777151Google Scholar
- 21.Praticò D, Iuliano L, Alessandri C, Camastra C, Violi F (1993) Polymorphonuclear leukocyte-derived O2-reactive species activate primed platelets in human whole blood. Am J Physiol 264:H1582–H1587Google Scholar
- 22.Davis JC, Hunt TK (1988) Problem wounds: the role of oxygen. Elsevier, New YorkGoogle Scholar
- 23.La Van FB, Hunt TK (1990) Oxygen and wound healing. Clin Plast Surg 17(3):463–72Google Scholar