Stem Cells Like Astrocytes: Various Roles
Adult stem cells have been identified in the brain, and continue to generate new neurons throughout life. These stem cells share a number of features with astrocytes, and recent evidence points to certain types of astrocytes capable of acquiring a stem-like phenotype. Stem cells have been implied as a potential origin for malignant glioma, especially glioblastoma multiforme (GBM), but are also known to react to a tumour by increased proliferation and migration towards the tumour mass. This apparent dichotomy between root and counteraction is discussed in this chapter, as well as the possibility of employing endogenous stem cells for brain cancer therapy.
KeywordsStem cells Astrocytes Tumor Brain Neurons NSC
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