Biomedical Integrated Instrumentation

  • Jordi Colomer-Farrarons
  • Pere Lluís Miribel-Català
Chapter
First Online:

Abstract

This Chapter is focused on the development of an integrated instrumentation to work with three electrodes amperometric Biosensor. First of all, it is introduced the conception of three electrodes configuration and how it works. Moreover, some typical electrochemical techniques like Voltammetry, EIS and amperometry, are introduced to the reader. The instrumentation electronics is based on a potentiostat architecture, which is explained in detail and experimentally validated. The obtained results with the full-custom approach are compared with the ones obtained using a commercial potentiostat. In that way, the correct operation of the designed circuits is fully validated. Furthermore, this chapter explains the conception of a Lock-In amplifier circuit used to detect the real and imaginary components of the complex impedance measured from the Biosensor. This circuit is theoretically explained and some simulated results are shown. Finally, the conception of Biotelemetry or how to transmit information from the subcutaneous device to the external reader is introduced. Then, the implemented protocol in this work is detailed. In summary, this chapter presents the developed BioChip IC that is able to drive the sensor, process the measured data and transmit the data to the external side through an inductive link.

Keywords

Analog integrated circuits Microelectronic implants Bioimpedance Amperometric sensors Electrochemical impedance spectroscopy Phase detection Active filters Biomedical telemetry 
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Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • Jordi Colomer-Farrarons
    • 1
  • Pere Lluís Miribel-Català
    • 1
  1. 1.Electronics DepartmentUniversity of BarcelonaBarcelonaSpain

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