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Monte Carlo Modeling of Light Transport in Tissue (Steady State and Time of Flight)

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Optical-Thermal Response of Laser-Irradiated Tissue

Abstract

Monte Carlo simulations are a fundamental and versatile approach toward modeling light transport in tissues. While diffusion theory for light transport is a fast and convenient way to model light transport, it fails when close to sources or boundaries and when absorption is strong compared to scattering; in other words, whenever conditions cause the gradient of fluence rate (or photon concentration) to not be simply linear but to have some curvature. Monte Carlo steps in to treat problems when diffusion theory fails. Figure 5.1 illustrates a Monte Carlo simulation.

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References

  1. Wilson BC and Adam G. A Monte Carlo model for the absorption and flux distributions of light in tissue. Med. Phys. 10:824–830 (1983).

    Article  Google Scholar 

  2. Keijzer M, Jacques SL, Prahl SA, and Welch AJ. Light distributions in artery tissue: Monte Carlo simulations for finite-diameter laser beams. Lasers Surg. Med. 9:148–154 (1989).

    Article  Google Scholar 

  3. Prahl, SA, Keijzer, Jacques SL, and Welch AJ. A Monte Carlo model of light propagation in tissue. In: G Müller and D Sliney (eds) Dosimetry of laser radiation in medicine and biology, SPIE Series, Vol. IS 5, pp. 102–111 (1989).

    Google Scholar 

  4. Wang L-H, Jacques SL, and Zheng L-Q. MCML – Monte Carlo modeling of photon transport in multi-layered tissues. Comput. Methods Programs Biomed., 47:131–146 (1995).

    Article  Google Scholar 

  5. Jacques, SL, http://omlc.ogi.edu/software/mc/mcml, Oregon Health & Science University, 2010. This site includes a 178-page manual on MCML. Also, a convolution program, CONV, is available for convolving the point spread functions generated by MCML.

  6. Wang LV. Monte Carlo Simulation Package. Modeling of Photon Transport in Multi-layered Tissues (Release 5: MCML 1.2.2 & CONV 1.1). http://labs.seas.wustl.edu/bme/Wang/mc.html, 2010.

  7. Jacques SL. Light distributions from point, line, and plane sources for photochemical reactions and fluorescence in turbid biological tissues. Photochem. Photobiol. 67:23–32 (1998).

    Article  Google Scholar 

  8. Jacques SL. mc321.c. Simple steady-state Monte Carlo program in spherical, cylindrical and planar coordinates (using ANSI standard C). http://omlc.ogi.edu/software/mc/mc321/index.html, 2007.

  9. Jacques SL. Monte Carlo simulations of fluorescence in turbid media, Ch. 6. In: MA Mycek and BW Pogue (eds) Handbook of biomedical fluorescence. Marcel-Dekker, New York, NY (2003).

    Google Scholar 

  10. Jacques, SL, http://omlc.ogi.edu/software/mc/mcsub, Oregon Health & Science University, 2010. This site lists the subroutine mcsub() that can be called by c programs to run a Monte Carlo simulation.

  11. Ramella-Roman JC, Prahl SA, and Jacques SL. Three Monte Carlo programs of polarized light transport into scattering media: part I. Opt. Express 13(12):4420–4438(2005).

    Article  ADS  Google Scholar 

  12. Ramella-Roman JC. Polarized light Monte Carlo. http://omlc.ogi.edu/software/polarization/index.html, 2005.

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Authors and Affiliations

  1. Biomedical Engineering Department, Oregon Health and Science University, Portland, OR, USA

    Steven L. Jacques

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  1. Steven L. Jacques
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Correspondence to Steven L. Jacques .

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Editors and Affiliations

  1. Dept. Biomedical Engineering, University of Texas, Austin, University Station 1, Austin, 78712, Texas, USA

    Ashley J. Welch

  2. Academic Medical Centre, Laser Centre, University of Amsterdam, Meibergdreef 9, Amsterdam, 1105 AZ, Netherlands

    Martin J.C. van Gemert

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Jacques, S.L. (2010). Monte Carlo Modeling of Light Transport in Tissue (Steady State and Time of Flight). In: Welch, A., van Gemert, M. (eds) Optical-Thermal Response of Laser-Irradiated Tissue. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-8831-4_5

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  • DOI: https://doi.org/10.1007/978-90-481-8831-4_5

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-8830-7

  • Online ISBN: 978-90-481-8831-4

  • eBook Packages: Physics and AstronomyPhysics and Astronomy (R0)

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