Circadian and Homeostatic Regulation of Sleepiness, Cognition, and Their Neuronal Underpinnings

  • Christina Schmidt
  • Christian Cajochen
  • Sarah L. Chellappa


In human beings, homeostatic and circadian sleep–wake regulatory processes work together for the maintenance of sleep and wakefulness at appropriate times within the 24-hour light-dark cycle. The interaction between these processes also determines time-of-day modulations in sleepiness and alertness levels, and affects performance in a series of cognitive tasks. Recent evidence suggests that similar modulation patterns can also be detected in the cerebral correlates underlying successful cognitive functions.


Sleep Deprivation Wake Regulation Circadian Phase Total Sleep Deprivation Morning Type 
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Copyright information

© Springer-Verlag Italia 2014

Authors and Affiliations

  • Christina Schmidt
    • 1
  • Christian Cajochen
    • 1
  • Sarah L. Chellappa
    • 2
  1. 1.Centre for ChronobiologyPsychiatric Hospital of the University of BaselBaselSwitzerland
  2. 2.Cyclotron Research CenterUniversity of LiègeLiègeBelgium

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