Catheter-related thrombosis is one of the late complications of totally implantable venous access port. Until now, few studies have introduced the practice of totally implantable venous access port in the clinical setting. On the basis of an extensive literature review, this chapter describes the definitions of various central venous catheter-related thrombosis, thrombogenic mechanism, clinical manifestations of thrombosis, diagnosis, prevention and treatment. The different incidence, catheter inserting technique, clinical presentations and treatment between adults and children are also demonstrated. The diagram, table and photographs from clinical cases are used to directly illustrate one of the most common complication of central venous access. The summary of both basic and clinical studies may help or serve as a guidance to provide clinical care for those in need of totally implantable venous access devices.
KeywordsCentral venous catheter Totally implantable venous access device Thrombosis Sleeve thrombus Fibrin sheaths Deep venous thrombosis Thrombolytic agents Anticoagulant Heparin Venography
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