Differenze di genere

  • Jon E. Grant
  • Suck W. Kim


L’idea dell’esistenza di differenze significative tra uomini e donne nei vari aspetti del gioco d’azzardo patologico (GAP) è un argomento che ha ricevuto crescente attenzione negli ultimi 5 anni. Nonostante il GAP sia considerato principalmente un problema maschile, la recente concentrazione sul GAP nelle donne ha portato l’attenzione su importanti differenze di genere nei campi dell’epidemiologia, della fenomenologia, della comorbidità psichiatrica e della biologia. Queste differenze hanno importanti implicazioni sui trattamenti. In questo capitolo, le scoperte che riguardano le differenze di genere sono passate in rassegna all’interno del contesto clinico.


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  1. Black DW, Moyer T: Clinical features and psychiatric comorbidity of subjects with pathological gambling behavior. Psychiatr Serv 49:1434–1439, 1998PubMedGoogle Scholar
  2. Blanco C, Petkova E, Ibáñez A, et al: A pilot placebo-controlled study of fluvoxamine for pathological gambling. Ann Clin Psychiatry 14:9–15, 2002PubMedGoogle Scholar
  3. Blaszczynski A, Steel Z, McConaghy N: Impulsivity in pathological gambling: the antisocial impulsivist. Addiction 92:75–87, 1997CrossRefPubMedGoogle Scholar
  4. Brady KT, Randall CL: Gender differences in substance use disorders. Psychiatr Clin North Am 22:241–252, 1999CrossRefPubMedGoogle Scholar
  5. Bukstein OG, Brent DA, Kaminer Y: Comorbidity of substance abuse and other psychiatric disorders in adolescents. Am J Psychiatry 146:1131–1141, 1989PubMedGoogle Scholar
  6. Crockford DN, el-Guebaly N: Psychiatric comorbidity in pathological gambling: a critical review. Can J Psychiatry 43:43–50, 1998PubMedGoogle Scholar
  7. Cunningham-Williams RM, Cottler LB, Compton WM III, et al: Taking chances: problem gamblers and mental health disorders—results from the St. Louis Epidemiologic Catchment Area Study. Am J Public Health 88:1093–1096, 1998CrossRefPubMedGoogle Scholar
  8. Eisen SA, Lin N, Lyons MJ, et al: Familial influences on gambling behavior: an analysis of 3359 twin pairs. Addiction 93:1375–1384, 1998CrossRefPubMedGoogle Scholar
  9. Grant JE, Kim SW: Demographic and clinical features of 131 adult pathological gamblers. J Clin Psychiatry 62:957–962, 2001CrossRefPubMedGoogle Scholar
  10. Grant JE, Kim SW: Gender differences in pathological gamblers seeking medication treatment. Compr Psychiatry 43:56–62, 2002CrossRefPubMedGoogle Scholar
  11. Grant JE, Kim SW, Brown E: Characteristics of geriatric patients seeking medication treatment for pathologic gambling disorder. J Geriatr Psychiatry Neurol 14:125–129, 2001CrossRefPubMedGoogle Scholar
  12. Grant JE, Kushner MG, Kim SW: Pathological gambling and alcohol use disorder. Alcohol Res Health 26:143–150, 2002Google Scholar
  13. Grant JE, Kim SW, Potenza MN, et al: Paroxetine treatment of pathological gambling: a multicenter randomized controlled trial. Int Clin Psychopharmacol 18:243–249, 2003CrossRefPubMedGoogle Scholar
  14. Haller R, Hinterhuber H: Treatment of pathological gambling with carbamazepine (letter). Pharmacopsychiatry 27:129, 1994CrossRefPubMedGoogle Scholar
  15. Helzer JE, Burnam A, McEvoy LT: Alcohol abuse and dependence, in Psychiatric Disorders in America: The Epidemiologic Catchment Area Study. Edited by Robins LN, Regier DA. New York, Free Press, 1991, pp 81–115Google Scholar
  16. Hollander E, Frenkel M, DeCaria C, et al: Treatment of pathological gambling with clomipramine (letter). Am J Psychiatry 149:710–711, 1992PubMedGoogle Scholar
  17. Hollander E, DeCaria CM, Mari E, et al: Short-term, single-blind fluvoxamine treatment of pathological gambling. Am J Psychiatry 155:1781–1783, 1998PubMedGoogle Scholar
  18. Hollander E, DeCaria CM, Finkell JN, et al: A randomized double-blind fluvoxamine/placebo crossover trial in pathologic gambling. Biol Psychiatry 47:813–817, 2000CrossRefPubMedGoogle Scholar
  19. Ibáñez A, de Castro IP, Fernandez-Piqueras J, et al: Pathological gambling and DNA polymorphic markers at MAO-A and MAO-B genes. Mol Psychiatry 5:105–109, 2000CrossRefPubMedGoogle Scholar
  20. Ibáñez A, Blanco C, Donahue E, et al: Psychiatric comorbidity in pathological gamblers seeking treatment. Am J Psychiatry 158:1733–1735, 2001CrossRefPubMedGoogle Scholar
  21. Ibáñez A, Blanco C, Moreyra P, et al: Gender differences in pathological gambling. J Clin Psychiatry 64:295–301, 2003CrossRefPubMedGoogle Scholar
  22. Kessler RC, McGonagle KA, Zhao S, et al: Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States: results from the National Comorbidity Survey. Arch Gen Psychiatry 51:8–19, 1994PubMedGoogle Scholar
  23. Kim SW, Grant JE: An open naltrexone treatment study of pathological gambling disorder. Int Clin Psychopharmacol 16:285–289, 2001aCrossRefPubMedGoogle Scholar
  24. Kim SW, Grant JE: Personality dimensions in pathological gambling disorder and obsessivecompulsive disorder. Psychiatry Res 104:205–212, 2001bCrossRefPubMedGoogle Scholar
  25. Kim SW, Grant JE, Adson DE, et al: Double-blind naltrexone and placebo comparison study in the treatment of pathological gambling. Biol Psychiatry 49:914–921, 2001CrossRefPubMedGoogle Scholar
  26. Kim SW, Grant JE, Adson DE, et al: A double-blind, placebo-controlled study of the efficacy and safety of paroxetine in the treatment of pathological gambling disorder. J Clin Psychiatry 63:501–507, 2002PubMedGoogle Scholar
  27. Ladd GT, Petry NM: Gender differences among pathological gamblers seeking treatment. Exp Clin Psychopharmacol 10:302–309, 2002CrossRefPubMedGoogle Scholar
  28. Ladouceur R, Sylvain C, Boutin C, et al: Cognitive treatment of pathological gambling. J Nerv Ment Dis 189:774–780, 2001CrossRefPubMedGoogle Scholar
  29. Linden RD, Pope HG Jr, Jonas JM: Pathological gambling and major affective disorder: preliminary findings. J Clin Psychiatry 47:201–203, 1986PubMedGoogle Scholar
  30. Mark ME, Lesieur HR: A feminist critique of problem gambling research. Br J Addiction 87:549–565, 1992CrossRefGoogle Scholar
  31. Martins SS, Lobo DS, Tavares H, et al: Pathological gambling in women: a review. Rev Hosp Clin Fac Med Sao Paulo 57:235–242, 2002PubMedGoogle Scholar
  32. McCormick RA, Russo AM, Ramirez LF, et al: Affective disorders among pathological gamblers seeking treatment. Am J Psychiatry 141:215–218, 1984PubMedGoogle Scholar
  33. Moskowitz JA: Lithium and lady luck: use of lithium carbonate in compulsive gambling. NY State J Med 80:785–788, 1980Google Scholar
  34. National Gambling Impact Study Commission: National Gambling Impact Study Commission Final Report. Washington, DC, National Gambling Impact Study Commission, 1999. Available at: http://govinfo.library.unt.edu/ngisc/reports/fullrpt.html. Accessed December 14, 2003.Google Scholar
  35. Pallanti S, Baldini Rossi N, Sood E, et al: Nefazodone treatment of pathological gambling: a prospective open-label controlled trial. J Clin Psychiatry 63:1034–1039, 2002aPubMedGoogle Scholar
  36. Pallanti S, Quercioli L, Sood E, et al: Lithium and valproate treatment of pathological gambling: a randomized single-blind study. J Clin Psychiatry 63:559–564, 2002bPubMedGoogle Scholar
  37. Perez de Castro I, Ibáñez A, Torres P, et al: Genetic association study between pathological gambling and a functional DNA polymorphism at the D4 receptor gene. Pharmacogenetics 7:345–348, 1997PubMedGoogle Scholar
  38. Perez de Castro I, Ibáñez A, Saiz-Ruiz J, et al: Genetic contribution to pathological gambling: possible association between a functional DNA polymorphism at the serotonin transporter gene (5-HTT) and affected men. Pharmacogenetics 9:397–400, 1999PubMedGoogle Scholar
  39. Petry NM: A comparison of young, middle-aged, and older adult treatmentseeking gamblers. The Gerontologist 42:92–99, 2002PubMedGoogle Scholar
  40. Potenza MN, Steinberg MA, McLaughlin SD, et al: Illegal behaviors in problem gambling: analysis of data from a gambling helpline. J Am Acad Psychiatry Law 28:389–403, 2000PubMedGoogle Scholar
  41. Potenza MN, Steinberg MA, McLaughlin SD, et al: Gender-related differences in the characteristics of problem gamblers using a gambling helpline. Am J Psychiatry 158:1500–1505, 2001CrossRefPubMedGoogle Scholar
  42. Randall CL, Roberts JS, Del Boca FK, et al: Telescoping of landmark events associated with drinking: a gender comparison. J Stud Alcohol 60:252–260, 1999PubMedGoogle Scholar
  43. Roy A, Adinoff B, Roehrich L, et al: Pathological gambling: a psychobiological study. Arch Gen Psychiatry 45:369–373, 1988PubMedGoogle Scholar
  44. Rubin A, Stout RL, Longabaugh R: Gender differences in relapse situations. Addiction 91 (suppl):111–120, 1996Google Scholar
  45. Shaffer HJ, Hall MN, Vander Bilt J: Estimating the prevalence of disordered gambling behavior in the United States and Canada: a research synthesis. Am J Public Health 89:1369–1376, 1999CrossRefPubMedGoogle Scholar
  46. Slutske WS, Eisen S, True WR, et al: Common genetic vulnerability for pathological gambling and alcohol dependence in men. Arch Gen Psychiatry 57:666–673, 2000CrossRefPubMedGoogle Scholar
  47. Slutske WS, Eisen S, Xian H, et al: A twin study of the association between pathological gambling and antisocial personality disorder. J Abnorm Psychol 110:297–308, 2001CrossRefPubMedGoogle Scholar
  48. Sylvain C, Ladouceur R, Boisvert JM: Cognitive and behavioral treatment of pathological gambling: a controlled study. J Consult Clin Psychol 65:727–732, 1997CrossRefPubMedGoogle Scholar
  49. Tavares H, Zilberman ML, Beites FJ, et al: Gender differences in gambling progression. J Gambl Stud 17:151–159, 2001CrossRefPubMedGoogle Scholar
  50. Trevorrow K, Moore S: The association between loneliness, social isolation, and women’s electronic gaming machine gambling. J Gambl Stud 14:263–284, 1998CrossRefGoogle Scholar
  51. Vitaro F, Arseneault L, Trenblay RE: Dispositional predictors of problem gambling in male adolescents. Am J Psychiatry 154:1769–1770, 1997PubMedGoogle Scholar
  52. Volberg RA: The prevalence and demographics of pathological gamblers: implications for public health. Am J Public Health 84:237–241, 1994CrossRefPubMedGoogle Scholar
  53. Zimmerman M, Breen RB, Posternak MA: An open-label study of citalopram in the treatment of pathological gambling. J Clin Psychiatry 63:44–48, 2002PubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia 2010

Authors and Affiliations

  • Jon E. Grant
    • 1
    • 2
  • Suck W. Kim
    • 3
  1. 1.Scuola di Medicina BrownProvidence
  2. 2.Clinica per i Disturbi da Controllo degli ImpulsiOspedale ButlerProvidence
  3. 3.Dipartimento di PsichiatriaUniversità del MinnesotaMinneapolis

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