Advertisement

Structure and Function of Protein

  • Kazuo Ohki
  • Hidetake Miyata
Chapter
Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)

Abstract

Each protein is synthetized according to its genetic information of amino acid sequence on DNA and the information of amino acid sequence determines three-dimensional structure of the protein. Major functions of proteins are enzyme, receptor and immunological antibody. Enzyme is the most important in them because metabolic system of cell is chemical reactions catalyzed by network of enzymes. Protein kinase and phosphatase is important system to regulate enzyme activity as well as allosteric regulation.

References

  1. 1.
    L. Michaelis, M. Menten, Biochem. Z. 49, 333 (1913)Google Scholar
  2. 2.
    E. Briggs, J.B.S. Haldane, Biochem. J. 19 (1925), 338(1925)CrossRefGoogle Scholar
  3. 3.
    Jacob, J. Monod, J. Mol. Biol. 3, 318 (1961)CrossRefGoogle Scholar
  4. 4.
    J. Monod, J. Wyman, J.P. Changeux, Mol. Biol. 12, 88 (1965)CrossRefGoogle Scholar
  5. 5.
    D.E. Koshland Jr., G. Nemethy, D. Filmer, Biochemistry 5, 365 (1966)CrossRefGoogle Scholar
  6. 6.
    S.J. Singer, G.L. Nicolson, Science 175, 720 (1972)ADSCrossRefGoogle Scholar
  7. 7.
    P.C. Jost, O.H. Griffith, R.A. Capaldi, G. Vanderkooi, Proc. Natl. Acad. Sci. USA 70, 480 (1973)ADSCrossRefGoogle Scholar
  8. 8.
    T. Tsukihara, T.H. Aoyama, E. Yamaashita, T. Tomizaki, H. Yamaguchi, H.K. Shinzawa-Itoh, R. Nakahima, R. Yaono, S. Yoshikawa, Science 269, 1069 (1995)ADSCrossRefGoogle Scholar
  9. 9.
    E.M. Landau, J.P. Rosenbusch, Proc. Natl. Acad. Sci. USA 93, 14532 (1996)ADSCrossRefGoogle Scholar
  10. 10.
    B. de Kruijff, Nature 386, 129 (1977)CrossRefGoogle Scholar
  11. 11.
    R.N. McElhaney, Biochim. Biophys. Acta 864, 361 (1986)CrossRefGoogle Scholar
  12. 12.
    J.C. Owicki, M.W. Springgate, H.M. McConnell, Proc. Natl. Acad. Sci. USA 75, 1616 (1978)ADSCrossRefGoogle Scholar
  13. 13.
    J.C. Owicki, H.M. McConnell, Proc. Natl. Acad. Sci. USA 76, 4750 (1979)ADSCrossRefGoogle Scholar
  14. 14.
    P.G. de Gennes, The Physics of Liquid Crystals (Oxford University Press, Oxford, 1974)zbMATHGoogle Scholar
  15. 15.
    O.G. Mouritsen, M. Bloom, Biophys. J. 46, 141 (1987)CrossRefGoogle Scholar
  16. 16.
    P. Walter, R. Gilmore, G. Blobel, Cell 38, 5 (1984)CrossRefGoogle Scholar

Copyright information

© Springer Japan KK, part of Springer Nature 2018

Authors and Affiliations

  • Kazuo Ohki
    • 1
  • Hidetake Miyata
    • 1
  1. 1.Department of PhysicsTohoku UniversitySendaiJapan

Personalised recommendations