In inflammatory bowel disease (IBD), confirmation of mucosal healing by endoscope has been recommended as a gold standard for complete remission.
In ulcerative colitis (UC), colonoscopic examination has been thought to be the most reliable approach to view all parts of the large intestine. Detecting the disease type of UC accurately by total colonoscope examination is very important, therefore a total colonoscope examination must be done at the time of diagnosis and starting induction therapy. And a surveillance program to detect dysplasia or early-stage colon cancer by diligent colonoscopic surveillance has been emphasized in UC.
In Crohn’s disease (CD) the diagnostic relevance of endoscopy remains unclear as compared with its established value in UC. CD lesions may appear at any site from the mouth to the perianal region; therefore, thorough examination from the upper parts of digestive track to the rectum should be examined by endoscope, including the small intestine being examined by capsule endoscopy or balloon endoscopy. The confirming of mucosal healing of involved CD lesion by endoscope examination is now strongly recommended because the achievement of mucosal healing of the involved lesion affects significantly the long-term prognosis at the stage of clinical remission after treatment.
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