Wheat Pathogens in China

  • Ming-guo Zhou
  • Xiao-jing Jia


Wheat production and consumption account for a major share of China’s food system (Du and Wang 2004), and Fusarium head blight (FHB), rusts, powdery mildew and sharp eyespot are the most important diseases on wheat, causing huge economic losses. They are generally treated by fungicides, except for rusts where resistant cultivars are widely grown. Resistance has developed to one or more fungicides, including the resistance of FHB to benzimidazole fungicides and of wheat powdery mildew to DMI fungicides. Besides resistance management, some fundamental research on fungicide resistance is also discussed.


Fusarium head blight Wheat powdery mildew Sharp eyespot Fungicide resistance Benzimidazole fungicides Carbendazim DMI fungicides Phenamacril Jinggangmycin Resistance management 


  1. Bai G, Shaner G (1994) Scab of wheat: prospects for control. Plant Dis 78(8):760–766CrossRefGoogle Scholar
  2. Bennett J, Klich M (2003) Mycotoxins. Clin Microbiol Rev 16:497–516PubMedCentralPubMedCrossRefGoogle Scholar
  3. Bollen GJ, Scholten G (1971) Acquired resistance to benomyl and some other systemic fungicides in a strain of Botrytis cinerea in cyclamen. Neth J Plant Pathol 77(3):83–90CrossRefGoogle Scholar
  4. Bottalico A (1998) Fusarium diseases of cereals: species complex and related mycotoxin profiles, in Europe. J Plant Pathol 80:85–103Google Scholar
  5. Chang DC, Grant GB, O’Donnell K, Wannemuehler KA, Noble-Wang J, Rao CY, Jacobson LM, Crowell CS, Sneed RS, Lewis FM (2006) Multistate outbreak of Fusarium keratitis associated with use of a contact lens solution. JAMA 296(8):953–963PubMedCrossRefGoogle Scholar
  6. Chen CJ, Yu JJ, Bi CW, Zhang YN, Xu JQ, Wang JX, Zhou MG (2009) Mutations in a β-tubulin confer resistance of Gibberella zeae to benzimidazole fungicides. Phytopathology 99(12):1403–1411PubMedCrossRefGoogle Scholar
  7. Chen C, Bi C, Yu J, Wang J, Li H, Luo Q, Zhou M (2008) MBC-resistance and its molecular mechanism in Gibberella zeae. J Plant Pathol 90:S2Google Scholar
  8. Chen L, Bai G, Desjardins A (2000) Recent advances in wheat head scab research in China. In: Raupp WJ, Ma Z, Chen P, Liu D (eds) Proceedings of international symposium wheat improvement for scab resistance. Nanjing Agricultural University, Jiangsu, pp 258–273 (in Chinese)Google Scholar
  9. Chen Y, Chen CJ, Wang JX, Jin LH, Zhou MG (2007) Genetic study on JS399-19 resistance in hyphal fusion of Fusarium graminearum by using nitrate nonutilizing mutants as genetic markers. J Genet Genom 34(5):469–476CrossRefGoogle Scholar
  10. Chen Y, Zhou MG (2009) Characterization of Fusarium graminearum isolates resistant to both carbendazim and a new fungicide JS399-19. Phytopathology 99(4):441–446PubMedCrossRefGoogle Scholar
  11. Dai DK, Jia XJ, Wu DX, Hou YP, Wang JX, Chen CJ, Zhou MG (2013) Analysis of diffusion path of carbendazim-resistance population of Fusarium head blight-based on Fusarium species, mycotoxin chemotype and resistance timing. Chine J Pestic Sci 15(3):279–285 (in Chinese with English Abstr)Google Scholar
  12. D’Mello JF, Macdonald AM, Postel D, Dijksma WT, Dujardin A, Placinta CM (1998) Pesticide use and mycotoxin production in Fusarium and Aspergillus phytopathogens. Eur J Plant Pathol 104(8):741–751CrossRefGoogle Scholar
  13. Dignani M, Anaissie E (2004) Human fusariosis. Clin Microbiol Infect 10(s1):67–75PubMedCrossRefGoogle Scholar
  14. Du W, Wang HH (2004) Price behavior in China’s wheat futures market. China Econ Rev 15(2):215–229CrossRefGoogle Scholar
  15. Duan YB, Zhang XK, Ge CY, Wang Y, Cao JH, Jia XJ, Wang JX, Zhou MG (2014) Development and application of loop-mediated isothermal amplification for detection of the F167Y mutation of carbendazim-resistant isolates in Fusarium graminearum. Scientific Reports, 4:7094Google Scholar
  16. Fan P, Zhang Y, Zhou M, Chen C, Wang J (2009) Incidence of trichothecenes in wheat-based foods from China. Int J Environ Anal Chem 89(4):269–276CrossRefGoogle Scholar
  17. Gu BG, Liu JF (1990) Research on MBC resistance of Fusarium head blight-II. Resistance monitoring and induction. J Nanjing Agric Univ 13(1):57–61 (in Chinese with English Abstr)Google Scholar
  18. Ioos R, Belhadj A, Menez M, Faure A (2005) The effects of fungicides on Fusarium spp. and Microdochium nivale and their associated trichothecene mycotoxins in French naturally-infected cereal grains. Crop Prot 24(10):894–902CrossRefGoogle Scholar
  19. Jing RL, Chang XP (2003) Genetic diversity in wheat (T. aestivum) germplasm resources with drought resistance. Acta Botanica Boreali-occidentalia Sinica 23(3):410 (in Chinese with English Abstr)Google Scholar
  20. Jones R, Mirocha C (1999) Quality parameters in small grains from Minnesota affected by Fusarium head blight. Plant Dis 83(6):506–511CrossRefGoogle Scholar
  21. Li HK, Chen CJ, Wang JX, Zhou MG (2006) Study on baseline-sensitivity of Fusarium graminearum to JS399-19 and assessment of the risk of resistance in vitro. Acta Phytopathol Sinica 36(3):273–278 (in Chinese with English Abstr)Google Scholar
  22. Li HX, Lu YJ, Wang JX, Zhou MG (2003) Cloning of β-tubulin gene from Gibberella zeae and analysis its relationship with carbendazim-resistance. Acta Microbiologica Sinica 43(4):424–429 (in Chinese with English Abstr)PubMedGoogle Scholar
  23. Liu X, Yu FW, Schnabel G, Wu JB, Wang ZY, Ma ZH (2011) Paralogous cyp51 genes in Fusarium graminearum mediate differential sensitivity to sterol demethylation inhibitors. Fungal Genet Biol 48:113–123PubMedCrossRefGoogle Scholar
  24. Luo Q, Xu J, Hou Y, Chen C, Wang J, Zhou M (2009) PIRA‐PCR for detection of Fusarium graminearum genotypes with moderate resistance to carbendazim. Plant Pathol 58(5):882–887CrossRefGoogle Scholar
  25. Matthies A, Buchenauer H (2000) Effect of tebuconazole (Folicur®) and prochloraz (Sportak®) treatments on Fusarium head scab development, yield and deoxynivalenol (DON) content in grains of wheat following artificial inoculation with Fusarium culmorum. Z PflKrankh PflSchutz 107(1):33–52Google Scholar
  26. McMullen M, Jones R, Gallenberg D (1997) Scab of wheat and barley: a re-emerging disease of devastating impact. Plant Dis 81(12):1340–1348CrossRefGoogle Scholar
  27. Miller SS, Chabot DMP, Ouellet T et al (2004) Use of a Fusarium graminearum strain transformed with green fluorescent protein to study infection in wheat (Triticum aestivum). Can J Plant Pathol 26:453–463CrossRefGoogle Scholar
  28. Milus E, Parsons C (1994) Evaluation of foliar fungicides for controlling Fusarium head blight of wheat. Plant Dis 78(7):697–699CrossRefGoogle Scholar
  29. O’Donnell K, Ward TJ, Geiser DM, Kistler HC, Aoki T (2004) Genealogical concordance between the mating type locus and seven other nuclear genes supports formal recognition of nine phylogenetically distinct species within the Fusarium graminearum clade. Fungal Genet Biol 41:600–623PubMedCrossRefGoogle Scholar
  30. Parry D, Jenkinson P, McLeod L (1995) Fusarium ear blight (scab) in small grain cereals – a review. Plant Pathol 44(2):207–238CrossRefGoogle Scholar
  31. Pirgozliev S, Edwards S, Hare M, Jenkinson P (2002) Effect of dose rate of azoxystrobin and metconazole on the development of Fusarium head blight and the accumulation of deoxynivalenol (DON) in wheat grain. Eur J Plant Pathol 108(5):469–478CrossRefGoogle Scholar
  32. Proctor RH, Hohn TM, McCormick SP (1995) Reduced virulence of Gibberella zeae caused by disruption of a trichothecene toxin biosynthetic gene. Mol Plant Microbe Interact 8(4):593–601PubMedCrossRefGoogle Scholar
  33. Qiu J, Xu J, Yu J, Bi C, Chen C, Zhou M (2011) Localisation of the benzimidazole fungicide binding site of Gibberella zeae β2‐tubulin studied by site-directed mutagenesis. Pest Manag Sci 67(2):191–198PubMedCrossRefGoogle Scholar
  34. Qiu J, Huang T, Xu J, Bi C, Chen C, Zhou M (2012) β‐Tubulins in Gibberella zeae: their characterization and contribution to MBC resistance. Pest Manag Sci 68(8):1191–1198PubMedCrossRefGoogle Scholar
  35. Schroeder W, Provvidenti R (1969) Resistance to benomyl in powdery mildew of cucurbits. Plant Dis Rep 53:271–275Google Scholar
  36. Seitz L, Eustace W, Mohr H, Shogren M, Yamazaki W (1986) Cleaning, milling, and baking tests with hard red winter wheat containing deoxynivalenol. Cereal Chem (USA) 63(2):146–150Google Scholar
  37. Snijders C (1990) Fusarium head blight and mycotoxin contamination of wheat, a review. Neth J Plant Pathol 96(4):187–198CrossRefGoogle Scholar
  38. Windels CE (2000) Economic and social impacts of Fusarium head blight: changing farms and rural communities in the northern Great Plains. Phytopathology 90:17–21Google Scholar
  39. Yang P, Zhang R, Duan X-Y, Zhou YL (2010) Sensitivity of Blumeria graminis f. sp. tritici isolates to triadimefon and quinoxyfen in China in 2008 and its cross-resistance between triadimefon and quinoxyfen. Acta Phytopathol Sinica 40(4):404–410Google Scholar
  40. Yearbook CS (2007) National Bureau of statistics of China. China Statistical Yearbook (in Chinese)Google Scholar
  41. Yuan SK, Ma YM, Zhou MG (2001) Germination of the cleistothecium of Blumeria graminis on wheat and its establishment of sensitive base-line to triadimefon. Plant Prot 27(1):1–3Google Scholar
  42. Yuan S, Zhou M (2005) A major gene for resistance to MBC, in field isolates of Gibberella zeae. Can J Plant Pathol 27(1):58–63CrossRefGoogle Scholar
  43. Zhang YJ, Yu JJ, Zhang YN, Zhang X, Cheng CJ, Wang JX, Hollomon DW, Fan PS, Zhou MG (2009a) Effect of MBC resistance on trichothecene production and aggressiveness of Fusarium graminearum. Mol Plant Microbe Interact 22(9):1143–1150PubMedCrossRefGoogle Scholar
  44. Zhang Y, Fan P, Zhang X, Chen C, Zhou M (2009b) Quantification of Fusarium graminearum in harvested grain by real-time polymerase chain reaction to assess efficacies of fungicides on Fusarium head blight, deoxynivalenol contamination, and yield of winter wheat. Phytopathology 99(1):95–100PubMedCrossRefGoogle Scholar
  45. Zhang YJ, Zhang X, Chen CJ, Zhou MG, Wang HC (2010) Effects of fungicides JS399-19, azoxystrobin, tebuconazole, and MBC on the physiological and biochemical indices and grain yield of winter wheat. Pestic Biochem Physiol 98(2):151–157CrossRefGoogle Scholar
  46. Zheng ZT, Gao T, Zhang Y, Hou YP, Wang JX, Zhou MG (2014) FgFim, a key protein regulating resistance to the fungicide JS399-19, asexual and sexual development, stress responses and virulence in Fusarium graminearum. Mol Plant Pathol 15(5):488–499PubMedCrossRefGoogle Scholar
  47. Zhou MG, Ye ZY, Liu JF (1994) Progress of fungicide resistance research. J Nanjing Agric Univ 17(3):33–41 (in Chinese with English Abstr)Google Scholar
  48. Zhou MG, Wang JX (2001) Study on sensitivity base-line of Fusarium graminearum to carbendazim and biological characters of MBC-resistant strains. Acta Phytopathol Sinica 31(4):365–370 (in Chinese with English Abstr)Google Scholar

Copyright information

© Springer Japan 2015

Authors and Affiliations

  1. 1.College of Plant ProtectionNanjing Agricultural UniversityNanjingChina

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