Intravenous regional sympathetic block (IRSB), a technique first described in 1974 byHannington-Kiff, is intravenous regional neural blockade. Local intravenous administration of guanethidine in patients with Sudeck’s atrophy and ischemic ulcer of the lower leg showed pain-relieving effects. In this method, a sympathetic blocking agent with local anesthetic is injected from a peripheral vein of affected limb whose proximal portion is tightened by tourniquet for CRPS; the effectiveness of steroids instead of guanethidine has also been reported.
KeywordsIRSB Reserpine Peripheral limb
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