Management During the Cooling Stage

  • Nariyuki Hayashi
  • Dalton W. Dietrich


The restoration of dying neurons and neuroprotection against secondary brain damage are the main goals of intensive care unit (ICU) management during the cooling stage of brain hypothermia treatment [22,24]. Management of neuroprotection against the progression of brain edema, ischemia, intracranial pressure (ICP) elevation, free radical attack, and neuroexcitation is not sufficient for severely brain-injured patients. Prior to neuroprotection management, restoration therapy should be considered for severely brain-injured patients affected by trauma, stroke, hypoxia, or cardiac arrest.


Enteral Nutrition Brain Edema Disseminate Intravascular Coagulation Algorithm Management Severe Brain Injury 
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Copyright information

© Springer Japan 2004

Authors and Affiliations

  • Nariyuki Hayashi
    • 1
    • 2
  • Dalton W. Dietrich
    • 3
    • 4
  1. 1.Nihon University Emergency Medical CenterTokyoJapan
  2. 2.Department of Emergency and Critical Care MedicineNihon University School of MedicineTokyoJapan
  3. 3.Department of Neurological Surgery, Neurology and Cell Biology and AnatomyUniversity of Miami School of MedicineMiamiUSA
  4. 4.The Miami Project to Cure ParalysisMiamiUSA

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