Die Geschichte der Zellkultur

  • Sabine Schmitz
Chapter
Part of the Experimentator book series (EXPERIMENTATOR)

Zusammenfassung

Die ersten Versuche, Gewebe bzw. Organe aus Spenderorganismen in vitrozu kultivieren, liegen schon sehr lange zuruck. Die Anfange der angewandten Gewebe- und Organkultur lassen sich etwa auf den Beginn des zwanzigsten Jahrhunderts zuruckdatieren. Mit der heute schon fast hochtechnisierten Art Zellen zu kultivieren, haben diese ersten Gehversuche nichts gemein. Damals beschaft igten sich nur einige wenige Wissenschaft ler mit solchen Dingen und dies machte sie zu Exoten unter ihren Kollegen. Diese Pioniere kampft en unerbittlich gegen die zahlreichen Kontaminationen, die nicht beherrschbar waren, an. Damals gab es weder Sicherheitswerkbanke, wie wir sie heute kennen, noch hatte man Antibiotika und Antimykotika zur Verfugung, die man zur Vermeidung von Infektionen mit Bakterien und Pilzen ins Nahrmedium geben konnte. Erst mit der Entdeckung des Penicillins Ende der 1920er-Jahre und der Entwicklung wirksamer Antimykotika war es moglich geworden, die Zellkulturplagen in den Griff zu bekommen. Auch die Standardmedien, wie sie heute in jedem Zellkulturlabor benutzt werden, wurden erst spater entwickelt.

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© Spektrum Akademischer Verlag Heidelberg 2011

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  • Sabine Schmitz

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