Plasmaprolactin in den verschiedenen Altersstufen
Zusammenfassung
Mit einer Doppelantikörpermethode (Cea-Ire-Sorin Kits) wurden radioimmunologisch die Normalwerte für Prolaktin beim männlichen Geschlecht in 3 Altersgruppen bestimmt (10–20 Jahre: 2,4 ± 1,2 ng/ml; 20–40 Jahre: 3,9 ± 1,5 ng/ml; 50–80 Jahre: 5,2 ± 3,8 ng/ml). Bei 10 Patienten mit einem Sertoli cell only syndrome fand sich ein Durchschnittswert für PRL von 3,08 ± 2,14 ng/ml. Bei 4 Patienten mit einem Prostatakarzinom im Stadium D (Zustand nach Hormonintervalltherapie und Orchiektomie) waren die PRL-Werte deutlich erhöht (13,1–18,7ng/ml).
Plasma Prolactin in Different Age Groups
Summary
After a detailed introduction to the problems of radioimmunological measurement of Prolactin and a review of the possible connections between PRL and urological and andrological diseases, respectively, the results of Prolactin measurements carried out with a Prolactin Radioimmunoassay Kit (Cea-Ire-Sorin) will be described. This Kit makes use of the “double antibody” method. In 99 healthy male subjects the plasma levels of Prolactin in 3 age groups were ascertained. These were as follows: Group I ages 10 to 20: 2.4 ± 1.2 ng/ml; group II ages 20 to 40: 3.9 ± 1.5 ng/ml; group III ages 50 to 80: 5.2 ± 3.8 ng/ml.
In the case of 10 patients suffering from Sertoli cell only syndrome, the mean level of PRL was: 3.08 ± 2.14 ng/ml.
In the cases of 4 patients suffering from prostate cancer stage D, treated with hormones at various intervals and after orchiectomy the range of PRL levels was 13.1–18.7 ng/ml.
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