Current Concepts of Measurement of Cerebrospinal Fluid Absorption and Biomechanics of Hydrocephalus

  • F. Gjerris
  • S. E. Børgesen
Part of the Advances and Technical Standards in Neurosurgery book series (NEUROSURGERY, volume 19)

Abstract

New investigate methods have extended the scientific and clinical knowledge of the circulation of the cerebrospinal fluid (CSF). Methods of measurement of resistance to CSF outflow have improved during the last 15 years (Børgesen et al. 1978; Ekstedt 1978; Shapiro et al. 1984; Kosteljanetz 1987; Gjerris et al. 1989 a). A thorough knowledge of the dynamic equilibrium between CSF production and absorption is essential for the understanding of the changes in the intracranial space during pathological conditions. CSF dynamics comprehend all factors concerning formation, flow rate, direction, and absorption of CSF.

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References

  1. 1.
    Albeck M, Gjerris F, Børgesen SE, Schmidt JF, Sørensen PS (1991) The resistance to cerebrospinal fluid outflow in healthy volunteers. J Neurosurg 74: 597–600PubMedCrossRefGoogle Scholar
  2. 2.
    Black PM, Griebel RW, Tzouras A, et al (1989) Pressure gradients and accessory absorption pathways in hydrocephalus. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 303–312Google Scholar
  3. 3.
    Brock M, Furuse M, Hasuo M, et al (1975) Influence of CSF-resorption pathways on intracranial capacitance. Adv Neurosurg 3: 109–113Google Scholar
  4. 4.
    Børgesen SE (1984) Conductance to outflow of CSF in normal pressure hydrocephalus. Acta Neurochir (Wien) 71: 1–45CrossRefGoogle Scholar
  5. 5.
    Børgesen SE, Gjerris F (1982) The predictive value of conductance to outflow of CSF in normal hydrocephalus. Brain 105: 65–86PubMedCrossRefGoogle Scholar
  6. 6.
    Børgesen SE, Gjerris F (1987) The relationships between intracranial pressure, ventricular size, and resistance to CSF outflow. J Neurosurg 67: 535–539PubMedCrossRefGoogle Scholar
  7. 7.
    Børgesen SE, Gjerris F, Schmidt J (1989) Measurement of resistance to CSF outflow by subarachnoid perfusion. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 121–129Google Scholar
  8. 8.
    Børgesen SE, Gjerris F, Sørensen SC (1978) The resistance to cerebrospinal fluid absorption in humans. Acta Neurol Scand 57: 88–96PubMedCrossRefGoogle Scholar
  9. 9.
    Børgesen SE, Sørensen SC, Olesen J, Gjerris F (1977) Spinal tumours associated with increased intracranial pressure. Acta Neurol Scand 56: 263–268PubMedCrossRefGoogle Scholar
  10. 10.
    Børgesen SE, Gjerris F, Sørensen SC (1979) Cerebrospinal fluid conductance and compliance of the craniospinal space in normal pressure hydrocephalus. A comparison between two methods for measuring conductance to outflow. J Neurosurg 51: 521–526PubMedCrossRefGoogle Scholar
  11. 11.
    Børgesen SE, Albeck MJ, Gjerris F, Czosnyka M (1991) Computerized infusion test compared to conventional lumbar-ventricular perfusion for measurement of resistance to CSF outflow. Acta Neurochir (Wien) submittedGoogle Scholar
  12. 12.
    Conner ES, Foley L, Black PM (1984) Experimental normal-pressure hydrocephalus is accompanied by increased transmantle pressure. J Neurosurg 61: 322–327PubMedCrossRefGoogle Scholar
  13. 13.
    Costabile G, Probst C, Schönholzer AM (1983) Further experiences with the intrathecal infusion test in the management of communicating hydrocephalus. In: Ishii S, Nagai H, Brock M (eds) Intracranial pressure V. Springer, Berlin Heidelberg New York, pp 632–635CrossRefGoogle Scholar
  14. 14.
    Crockard HA, Hanlon K, Duda EE, et al (1977) Hydrocephalus as a cause of dementia: Evaluation by computerized tomography and intracranial pressure monitoring. J Neurol Neurosurg Psychiatry 40: 736–740PubMedCrossRefGoogle Scholar
  15. 15.
    Cserr HF (1989) Flow of CSF and brain interstitial fluid (ISF) into deep cervical lymph. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 58–63Google Scholar
  16. 16.
    Cserr HF, Cooper DN, Milhorat H (1977) Flow of cerebral interstitial fluid as indicated by the removal of extracellular markers from rat caudate nucleus. Exp Eye Res 25 [Suppl]: 461–473PubMedCrossRefGoogle Scholar
  17. 17.
    Czosnyka M, Wollk-Laniewski D, Darwaj P, et al (1989) Software for neurosurgery intensive care. In: Hoff JT, Betz Al (eds) Intracranial pressure VII. Springer, Berlin Heidelberg New York, pp 84–87CrossRefGoogle Scholar
  18. 18.
    Dacey RG, Welch JE, Winn HR, et al (1980) Bacterial meningitis: Changes in CSF outflow resistance. In: Shulman K, Marmarou A, Miller JD, et al (eds) Intracranial pressure IV. Springer, Berlin Heidelberg New York, pp 350–353CrossRefGoogle Scholar
  19. 19.
    Davson H, Hollingworth G, Segal MB (1970) The mechanism of drainage of the cerebrospinal fluid. Brain 93: 665–678PubMedCrossRefGoogle Scholar
  20. 20.
    Davson H, Welch K, Segal MB (1987) The physiology and pathophysiology of the cerebrospinal fluid. Churchill Livingstone, Edinburgh, pp 1013Google Scholar
  21. 21.
    Di Rocco C, Pettorossi VE, Mancinelli R, Velardi F (1978) Communicating hydrocephalus induced by mechanically increased amplitude of the intraventricular cerebrospinal fluid pressure: Experimental studies. Exp Neurol 59: 40–52PubMedCrossRefGoogle Scholar
  22. 22.
    Doczi T, Bodosi M (1989) The central neuroendocrine regulation of brain water and electrolytes, and resorption of cerebrospinal fluid (CSF). In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 282–291Google Scholar
  23. 23.
    Early CB, Fink LH (1976) Some fundamental applications of the law of La Place in neurosurgery. Surg Neurol 6: 185–189Google Scholar
  24. 24.
    Ekstedt J (1977) CSF hydrodynamic studies in man. Method of constant pressure CSF infusion. J Neurol Neurosurg Psychiatry 40: 105–119PubMedCrossRefGoogle Scholar
  25. 25.
    Ekstedt J (1978) CSF hydrodynamic studies in man. J Neurol Neurosurg Psychiatry 41: 345–353PubMedCrossRefGoogle Scholar
  26. 26.
    Ekstedt J, Fridén H (1989) Estimation of CSF outflow resistance in humans: infusion methods. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 148–165Google Scholar
  27. 27.
    Fishman RA (1980) Cerebrospinal fluid in diseases of the nervous system. WB Saunders Company, Philadelphia, pp 384Google Scholar
  28. 28.
    Friden HG, Ekstedt J (1989) Estimation of CSF outflow resistance: Model validation and resistance calculation by method of CSF volume accounting. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 198–210Google Scholar
  29. 29.
    Gjerris Annette (1988) Baseline studies on transmitter substances on cerebrospinal fluid in depression (Thesis). Acta Neurol Scand 78 [Suppl 346]: 1–35Google Scholar
  30. 30.
    Gjerris Annette, Gjerris F, Sørensen PS, et al (1988) Do concentrations of neurotransmitters measured in lumbar cerebrospinal fluid reflect the concentrations at brain level? Acta Neurochir (Wien) 91: 55–59CrossRefGoogle Scholar
  31. 31.
    Gjerris F, Børgesen SE (1992) Pathophysiology of the cerebrospinal fluid circulation. In: Crockard A, Hayward R, Hoff JT (eds) Neurosurgery, the scientific basis of clinical practice, 2nd ed. Blackwells Scientific Publications, OxfordGoogle Scholar
  32. 32.
    Gjerris F, Børgesen SE, Hoppe E, et al (1982) The conductance to outflow of CSF in adults with high pressure hydrocephalus. Acta Neurochir (Wien) 64: 59–67CrossRefGoogle Scholar
  33. 33.
    Gjerris F, Børgesen SE, Sørensen PS (eds) (1989 a) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 400Google Scholar
  34. 34.
    Gjerris F, Børgesen SE, Schmidt J, Sørensen PS (1989 b) Resistance to cerebrospinal fluid outflow in patients with normal pressure hydrocephalus. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 329–338Google Scholar
  35. 35.
    Gjerris F, Børgesen SE, Sørensen PS, Boesen F, Schmidt K, Harmsen A, Lester J (1987) Resistance to cerebrospinal fluid outflow and intracranial pressure in patients with hydrocephalus after subarachnoid haemorrhage. Acta Neurochir (Wien) 88: 79–86CrossRefGoogle Scholar
  36. 36.
    Gjerris F, Børgesen SE, Schmidt K, Sørensen PS, Gyring J (1986) Measurement of conductance to cerebrospinal fluid outflow by the steady-state perfusion method in patients with normal or increased intracranial pressure. In: Miller JD, Teasdale GM, Rowan JO, Galbraith SL, Mendelow AD (eds) Intracranial pressure VI. Springer, Berlin Heidelberg New York, pp 411–416Google Scholar
  37. 37.
    Gjerris F, Snorrason E. Hydrocephalus during historical time (1992) J Hist Neurosci; submittedGoogle Scholar
  38. 38.
    Gjerris F, Sørensen PS, Vorstrup S, Paulson OB (1985) Conductance to cerebrospinal fluid outflow, intracranial pressure and cerebral blood flow in patients with benign intracranial hypertension. Ann Neurol 17: 158–162PubMedCrossRefGoogle Scholar
  39. 39.
    Gyring J, Gjerris F, Brøndsted HE, Andersen NEO (1986) CSF outflow resistance: No current model is satisfactory. In: Miller JD, Teasdale GM, Rowan JO, Galbraith SL, Mendelow AD (eds) Intracranial pressure VI. Springer, Berlin Heidelberg New York, pp 111–117Google Scholar
  40. 40.
    Gyring J, Gutschik E, Gjerris F (1989) Resistance to CSF outflow in experimental pneumococcal meningitis. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 80–90Google Scholar
  41. 41.
    Hakim S, Hakim C (1984) A biochemical model of hydrocephalus and its relationship to treatment. In: Shapiro K, Marmarou A, Portnoy H (eds) Hydrocephalus. Raven Press, New York, pp 143–177Google Scholar
  42. 42.
    Hansen K, Gjerris F, Sørensen PS (1987) Absence of hydrocephalus in spite of impaired cerebrospinal fluid absorption and severe intracranial hypertension. Acta Neurochir (Wien) 86: 93–97CrossRefGoogle Scholar
  43. 43.
    Hochwald G (1984) Animal models of hydrocephalus. In: Shapiro K, Marmarou A, Portnoy H (eds) Hydrocephalus. Raven Press, New York, pp 199–213Google Scholar
  44. 44.
    Hoff J, Barber R (1974) Transcerebral mantle pressure in normal pressure hydrocephalus. Arch Neurol 31: 101–105PubMedCrossRefGoogle Scholar
  45. 45.
    Jeffreys RV, Wood MM (1978) Adult non-tumorous dementia and hydrocephalus. Acta Neurochir (Wien) 45: 103–114CrossRefGoogle Scholar
  46. 46.
    Katzman R, Hussey F (1970) A simple constant/infusion manometric test for measurement of CSF absorption. Neurology (Minneap) 20: 534–544Google Scholar
  47. 47.
    Kaufman HH, Carmel PW (1978) Aseptic meningitis and hydrocephalus after posterior fossa surgery. Acta Neurochir (Wien) 44: 179–196CrossRefGoogle Scholar
  48. 48.
    Kosteljanetz M (1985) Resistance to outflow of cerebrospinal fluid determined by bolus injection technique and constant rate steady infusions in humans. Neurosurg 16: 336–340CrossRefGoogle Scholar
  49. 49.
    Kosteljanetz M (1987) Intracranial pressure: cerebrospinal fluid dynamics and pressure-volume relations (Thesis). Acta Neurol Scand 75 [Suppl]: 111CrossRefGoogle Scholar
  50. 50.
    Kosteljanetz M (1989) Measurement of resistance to outflow: The bolus injection method. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 134–143Google Scholar
  51. 51.
    Kosteljanetz M, Nehen AM, Kaalund J (1990) Cerebrospinal fluid outflow resistance measurements in the selection of patients for shunt surgery in the normal pressure hydrocephalus syndrome. A controlled trial. Acta Neurochir (Wien) 104: 48–53CrossRefGoogle Scholar
  52. 52.
    Lorenzo AV, Page KK, Waters GV (1970) Relationship between cerebrospinal fluid formation, absorption, and pressure in human hydrocephalus. Brain 93: 679–692PubMedCrossRefGoogle Scholar
  53. 53.
    Lundar T, Nornes H (1990) Determination of ventricular fluid outflow resistance in patients with ventriculomegaly. J Neurol Neurosurg Psychiatry 53: 896–989PubMedCrossRefGoogle Scholar
  54. 54.
    Lying-Tunell U (1978) Quantitative cisternography. Acta Radiol Diagn 19: 905–917Google Scholar
  55. 55.
    Marmarou A, Shulman K, LaMorgese J (1975) Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system. J Neurosurg 43: 523–534PubMedCrossRefGoogle Scholar
  56. 56.
    Marmarou A, Shulman K, Rosende RM (1978) A non-linear analysis of CSF system and intracranial pressure dynamics. J Neurosurg 48: 332–344PubMedCrossRefGoogle Scholar
  57. 57.
    Marmarou A, Ward JD, Wachi A, Young HF (1989) Contribution of CSF outflow resistance to ICP rise in head-injured patients. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 356–365Google Scholar
  58. 58.
    Marmarou A, Tabaddor K (1987) Intracranial pressure: Physiology and pathophysiology. In: Cooper PR (ed) Head injury, 2nd ed. Williams & Wilkins, Baltimore, pp 159–176Google Scholar
  59. 59.
    McComb JG (1983) Recent research into the nature of cerebrospinal fluid formation and absorption. J Neurosurg 59: 369–383PubMedCrossRefGoogle Scholar
  60. 60.
    Milhorat TH (1972) Hydrocephalus and the cerebrospinal fluid. Williams & Wilkins, Baltimore, pp 550Google Scholar
  61. 61.
    Palma A, Kolberg T, Wust R, Entzian W (1978) New aspects of cerebrospinal fluid dynamics in humans investigated by sequential gamma camera cisternography, with data evaluation by digital multichannel analyzer. Acta Neurochir (Wien) 45: 53–88CrossRefGoogle Scholar
  62. 62.
    Pappenheimer JR, Heisey SR, Jordan EF, et al (1962) Perfusion of the cerebral ventricular system in unanaesthetized goats. Am J Physiol 203: 763–774Google Scholar
  63. 63.
    Penn RD, Bacus JW (1984) The brain as a sponge: A computed tomographic look at Hakims’s hypothesis. Neurosurgery 14: 670–674PubMedCrossRefGoogle Scholar
  64. 64.
    Pollay M (1975) Formation of cerebrospinal fluid. J Neurosurg 42: 665–673PubMedCrossRefGoogle Scholar
  65. 65.
    Pollay M (1985) The pathophysiology of the cerebrospinal fluid circulation. In: Crockard A, Hayward R, Hoff JT (eds) Neurosurgery, the scientific basis of clinical practice. Blackwells Scientific Publications, Oxford, pp 279–296Google Scholar
  66. 66.
    Pollay M, Stevens FA, Roberts PA (1983) Alteration in choroid-plexus blood flow and cerebrospinal-fluid formation by increased ventricular pressure. In: Wood JH (ed) Neurobiology of cerebrospinal fluid 2. Plenum Press, New York London, pp 687–695Google Scholar
  67. 67.
    Portnoy HD (1989) The physics of hydrocephalus: the Laplacian model. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 315–333Google Scholar
  68. 68.
    Portnoy HD, Croissant PD (1976) A practical method for measuring hydrodynamics in hydrocephalus. Surg Neurol 5: 273–277PubMedGoogle Scholar
  69. 69.
    Powell M, Crockard A, Brookes D (1989) Normal pressure hydrocephalus — ICP and Pet scan studies before and after shunting. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 377–386Google Scholar
  70. 70.
    Price DJ (1989) The clinical value of measurement of CSF outflow resistance. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 390–398Google Scholar
  71. 71.
    Raichle ME (1981) Hypothesis: A central neuroendocrine system regulates brain ion homeostasis and volume. In: Martin JB, Reichlin S, Bick KL (eds) Neurosecretion and brain peptides. Raven Press, New York, pp 329–336Google Scholar
  72. 72.
    Rekate HL, Olivero WM, McCormick J, et al (1989) Resistance elements within the cerebrospinal fluid circulation. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cereobrospinal fluid. Munksgaard, Copenhagen, pp 45–52Google Scholar
  73. 73.
    Rekate HL, Williams F, Chisek HJ, et al (1988) The application of mathematical modeling to hydrocephalus research. In: Marlin AE (ed) Concepts in paediatric neurosurgery, vol 8. Karger, Basel, pp 1–14Google Scholar
  74. 74.
    Sahar A (1979) Experimental progressive hydrocephalus in the young animal Child’s Brain 5: 14–23Google Scholar
  75. 75.
    Sahar A, Feinsod M, Beller AJ (1980) Choroid plexus papilloma: Hydrocephalus and cerebrospinal fluid dynamics. Surg Neurol 13: 476–478PubMedGoogle Scholar
  76. 76.
    Sahar A, Hochwald GM, Ransohoff J (1971) Cerebrospinal fluid turnover in experimental hydrocephalic dogs. Neurology 21: 218–224PubMedGoogle Scholar
  77. 77.
    Sahar A, Hochwald GM, Sadik AR, Ransohoff J (1969) Cerebrospinal fluid absorption. Arch Neurol 21: 638–644PubMedCrossRefGoogle Scholar
  78. 78.
    Sainte-Rose J, Hoffman HJ, Hirsch JF (1989) Shunt failure. Concepts in paediatric neurosurgery 9: 7–20Google Scholar
  79. 79.
    Schmidt JF, Fedders O, Børgesen SE, Gjerris F (1989) Reproducibility of measurements of resistance to CSF outflow. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 400Google Scholar
  80. 80.
    Serlo W, Fernell E, Heikkinen E, Anderson H, von Wendt L (1990) Functions and complications of shunts in different aetiologies of childhood hydrocephalus. Child’s Nerv Syst 6: 92–94CrossRefGoogle Scholar
  81. 81.
    Shapiro K (1989) Influences of the skull and dura on the resistance to CSF outflow. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of cerebrospinal fluid. Munksgaard, Copenhagen, pp 215–221Google Scholar
  82. 82.
    Shapiro K, Marmarou A, Portnoy H (eds) (1984) Hydrocephalus. Raven Press, New York, pp 401Google Scholar
  83. 83.
    Shapiro K, Marmarou A, Shulman K (1980) Characterization of clinical CSF dynamics and neural axis compliance using the pressure-volume index: I. The normal pressure-volume index. Ann Neurol 7: 508–514PubMedCrossRefGoogle Scholar
  84. 84.
    Sklar FH, Beyer CW, Ramanathan M, Cooper PR, Clark WK (1979) Cerebrospinal fluid dynamics in patients with pseudo tumour cerebri. Neurosurgery 5: 208–216PubMedCrossRefGoogle Scholar
  85. 85.
    Sklar FH, Beyer CW, Ramanathan M, et al (1978) Servo-controlled lumbar infusions: A clinical tool for determination of CSF dynamics as a function of pressure. Neurosurgery 3: 170–175PubMedCrossRefGoogle Scholar
  86. 86.
    Sprung C, Collmann H, Fuchs EC, et al (1977) Pre-and postoperative evaluation of hydrocephalus using the infusion test. Adv Neurosurg 4: 161–175CrossRefGoogle Scholar
  87. 87.
    Stensen N (1669) De vitulo hydrocephalo epistola. In: Berryat: Coll. Acad. Part. Etrang., Parisiis, 1769; VII: 188–191, Th. Bartholin T: Acta Med. & Phil. Hafn. 1673; I: 249–262, Th. Bonet: Medicina Septentrional. Genevre, 1686, liber 1 sect. II cap. VI: 25–28, Le Clerc & Manget: Bibl. Anat., Genevre, 1685; II-335–38, Maar, Vilh.: Nicolai Stenonis Opera Philosophica. Kbhvn.: V. Tryde, 1950; II: 227–237 og Harriet M. Hansen (ed.): Niels Stensen’s Korrespondance i dansk Oversrettelse. (in Danish) Kbhvn.: C. A. Reitzel, 1987; I: 137–146Google Scholar
  88. 88.
    Steiner L, Løfgren J, Zwetnow N (1975) Lethal mechanism in repeated subarachnoid haemorrhage in dogs. Acta Neurol Scand 52: 241–267PubMedCrossRefGoogle Scholar
  89. 89.
    Steinbok P, Thompson GB (1976) Complications of ventriculo-vascular shunts: Computer analysis of aetiological factors. Surg Neurol 5: 31–35PubMedGoogle Scholar
  90. 90.
    Sullivan HG, Miller JD, Griffith RL, et al (1979) Bolus versus steady-state infusion for determination of CSF outflow resistance. Ann Neurol 5: 228–238PubMedCrossRefGoogle Scholar
  91. 91.
    Sørensen PS (1986) Studies of vasopressin in the human CSF (Thesis). Acta Neurol Scand 74: 81–102PubMedCrossRefGoogle Scholar
  92. 92.
    Sørensen PS, Gjerris F, Schmidt J (1989 a) Resistance to CSF outflow in benign intracranial hypertension. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of the cerebrospinal fluid. Munksgaard, Copenhagen, pp 343–352Google Scholar
  93. 93.
    Sørensen PS, Gjerris F, Hammer M (1984) Cerebrospinal fluid vasopressin and increased intracranial pressure. Ann Neurol 15: 435–440PubMedCrossRefGoogle Scholar
  94. 94.
    Sørensen PS, Gyring JA (1990) Intracerebroventricular infusion but not bolus injection of vasopressin increases the cerebrospinal fluid pressure in awake rabbits. Neurol Res 12: 83–88PubMedGoogle Scholar
  95. 95.
    Sørensen PS, Thomsen C, Gjerris F, et al (1989 b) Increased brain water content in pseudo tumour cerebri measured by magnetic resonance imaging of brain water self diffusion. Neurol Res 11: 160–164PubMedGoogle Scholar
  96. 96.
    Tans TJ, Poortvliet DCJ (1983) Steady-state and bolus infusions in hydrocephalus. In: Ishii S, Nagai H, Brock M (eds) Intracranial pressure V. Springer, Berlin Heidelberg New York, pp 636–640CrossRefGoogle Scholar
  97. 97.
    Tans TJ, Poortvliet DCJ (1989) Significance of compliance in adult hydrocephalus. In: Gjerris F, Børgesen SE, Sørensen PS (eds) Outflow of the cerebrospinal fluid. Munksgaard, Copenhagen, pp 272–279Google Scholar
  98. 98.
    Teasdale G, Grant R, Condon D, et al (1989) Measurement of cranial CSF volumes in normal subjects. In: Gjerris F, Børgesen SE, Søfensen PS (eds) Outflow of the cerebrospinal fluid. Munksgaard, Copenhagen, pp 258–268Google Scholar
  99. 99.
    Thomsen C, Henriksen O, Ring P (1987) In vivo measurement of water self diffusion in the human brain by magnetic resonance imaging. Acta Radiol 28: 355–361Google Scholar
  100. 100.
    Vaneste J, Van Acker R (1990) Normal pressure hydrocephalus: Did publications alter management? J Neurol Neurosurg Psychiatry 53: 564–568CrossRefGoogle Scholar
  101. 101.
    Voldby B (1986) Ruptured intracranial aneurysm. A clinical and pathophysiological study (Thesis). Dan Med Bull 33: 53–64PubMedGoogle Scholar
  102. 102.
    Vorstrup S, Christensen J, Gjerris F, Sørensen PS, Thomsen AM, Paulson OP (1987) Cerebral blood flow in patients with normal-pressure hydrocephalus before and after shunting. J Neurosurg 66: 379–387PubMedCrossRefGoogle Scholar
  103. 103.
    Welch K (1975) The principles of physiology of the cerebrospinal fluid in relation to hydrocephalus including normal pressure hydrocephalus. In: Friedlander WJ (ed) Advances in neurology. Current reviews. Raven Press, New York, pp 345–375Google Scholar
  104. 104.
    Weller RO, Mitchell J (1980) Cerebrospinal fluid oedema and its sequelae in hydrocephalus. Adv Neurol 28: 111–123PubMedGoogle Scholar
  105. 105.
    Wood JH (ed) (1980) Neurobiology of cerebrospinal fluid. Plenum Press, New York London, pp 1101Google Scholar
  106. 106.
    Wood JH (ed) (1983) Neurobiology of cerebrospinal fluid 2. Plenum Press, New York London, pp 961Google Scholar

Copyright information

© Springer-Verlag/Wien 1992

Authors and Affiliations

  • F. Gjerris
    • 1
  • S. E. Børgesen
    • 1
  1. 1.The University Clinic of Neurosurgery, RigshospitaletCopenhagenDenmark

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