Biomarkers of Acute Aortic Syndrome

  • Toru SuzukiEmail author
  • Daigo Sawaki


Acute aortic syndrome (acute aortic dissection, AAD; intramural hematoma, IMH; and penetrating atherosclerotic ulcer, PAU) is a disease entity which possesses high mortality rate during the acute phase even in the current era. AAD, especially, has a broad variety of symptoms at onset, and frequently its diagnosis is delayed resulting in worse prognosis. Development and improvement of biomarkers have been pursued to enable the early diagnosis of AAD at “point of care” for immediate decision for further imaging or discrimination from other diseases such as coronary artery disease or pulmonary embolism.


Acute aortic syndrome Biomarker Dissection Genetics Proteins Inflammation 


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  1. 1.University of LeicesterLeicesterUK
  2. 2.University Hospitals of Leicester NHS TrustLeicesterUK
  3. 3.Department of Cardiovascular Sciences, Cardiovascular Research Centre, Glenfield General HospitalUniversity of LeicesterLeicesterUK
  4. 4.INSERM U955-Biomedical Research of Mondor InstituteUniversity of Paris East Créteil-Henri Mondor HospitalParisFrance

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