History and Definition of Delayed Cerebral Ischemia
Abstract
A list of the vasospasm meetings is provided. The early descriptions of angiographic vasospasm and delayed cerebral ischemia are presented. Selected advances in knowledge in the field and some controversies are described. A proposal for definitions of neurological deterioration due to delayed cerebral ischemia, of cerebral infarction, and of vasospasm is reviewed.
Keywords
Vasospasm History Delayed cerebral ischemia Subarachnoid hemorrhageNotes
Conflicts of Interest
RLM receives grant support from the Physicians Services Incorporated Foundation and is a stockholder of Edge Therapeutics. RLM, RTH, EK, SAM, AMo, AR, PV, IW, and NK are consultants for Actelion Pharmaceuticals. SAM is a consultant for Edge Theraputics. RLM is Chief Scientific Officer of Edge Theraputics. EK has been on advisory boards for Roche Diagnostics, and is a stockholder in NeMoDevices. AMo has been a consultant for Micrus Endovascular and Covidien. PV is a consultant for Aesculap. IW is a consultant for Boston Scientific, ev3, and BALT, and receives a departmental grant from Boston Scientific. DB, AF, AMa, and SR are employees and stockholders of Actelion Pharmaceuticals.
References
- 1.Aaslid R, Markwalder TM, Nornes H (1982) Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries. J Neurosurg 57:769–774PubMedCrossRefGoogle Scholar
- 2.Crowley RW, Medel R, Dumont AS, Ilodigwe D, Kassell NF, Mayer SA, Ruefenacht D, Schmiedek P, Weidauer S, Pasqualin A, Macdonald RL (2011) Angiographic vasospasm is strongly correlated with cerebral infarction after subarachnoid hemorrhage. Stroke 42:919–923PubMedCrossRefGoogle Scholar
- 3.Dankbaar JW, Rijsdijk M, van der Schaaf IC, Velthuis BK, Wermer MJ, Rinkel GJ (2009) Relationship between vasospasm, cerebral perfusion, and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. Neuroradiology 51:813–819PubMedCrossRefGoogle Scholar
- 4.Dorsch N (2011) A clinical review of cerebral vasospasm and delayed ischaemia following aneurysm rupture. Acta Neurochir Suppl 110:5–6PubMedCrossRefGoogle Scholar
- 5.Dorsch NWC, King MT (1994) A review of cerebral vasospasm in aneurysmal subarachnoid hemorrhage. Part 1: incidence and effects. J Clin Neurosci 1:19–26PubMedCrossRefGoogle Scholar
- 6.Dreier JP, Korner K, Ebert N, Gorner A, Rubin I, Back T, Lindauer U, Wolf T, Villringer A, Einhaupl KM, Lauritzen M, Dirnagl U (1998) Nitric oxide scavenging by hemoglobin or nitric oxide synthase inhibition by N-nitro-L-arginine induces cortical spreading ischemia when K+ is increased in the subarachnoid space. J Cereb Blood Flow Metab 18:978–990PubMedCrossRefGoogle Scholar
- 7.Ecker A, Riemenschneider PA (1951) Arteriographic demonstration of spasm of the intracranial arteries with special reference to saccular arterial aneurysms. J Neurosurg 8:660–667PubMedCrossRefGoogle Scholar
- 8.Fisher CM (1975) Clinical syndromes in cerebral thrombosis, hypertensive hemorrhage, and ruptured saccular aneurysm. Clin Neurosurg 22:117–147PubMedGoogle Scholar
- 9.Fisher CM, Kistler JP, Davis JM (1980) Relation of cerebral vasospasm to subarachnoid hemorrhage visualized by computerized tomographic scanning. Neurosurgery 6:1–9PubMedCrossRefGoogle Scholar
- 10.Fisher CM, Roberson GH, Ojemann RG (1977) Cerebral vasospasm with ruptured saccular aneurysm – the clinical manifestations. Neurosurgery 1:245–248PubMedCrossRefGoogle Scholar
- 11.Grubb RLJ, Raichle ME, Eichling JO, Gado MH (1977) Effects of subarachnoid hemorrhage on cerebral blood volume, blood flow, and oxygen utilization in humans. J Neurosurg 46:446–453PubMedCrossRefGoogle Scholar
- 12.Gull WM (1859) Cases of aneurism of the cerebral vessels. Guys Hosp Rep 5:281–304Google Scholar
- 13.Ibrahim GM, Weidauer S, Vatter H, Raabe A, Macdonald RL (2012) Attributing hypodensities on CT to angiographic vasospasm is not sensitive and unreliable. Stroke 43:109–112PubMedCrossRefGoogle Scholar
- 14.Katada K, Kanno T, Sano H, Shibata T, Shah MY (1977) Computed tomography of ruptured intracranial aneurysm in acute stage [author’s transl]. No Shinkei Geka 5:955–963PubMedGoogle Scholar
- 15.Millikan CH (1975) Cerebral vasospasm and ruptured intracranial aneurysm. Arch Neurol 32:433–449PubMedCrossRefGoogle Scholar
- 16.Ponce FA, Lozano AM (2010) Highly cited works in neurosurgery. Part I: the 100 top-cited papers in neurosurgical journals. J Neurosurg 112:223–232PubMedCrossRefGoogle Scholar
- 17.Robertson EG (1949) Cerebral lesions due to intracranial aneurysms. Brain 72:150–185PubMedCrossRefGoogle Scholar
- 18.Suzuki Y, Lederis K, Huang M, Leblanc FE, Rorstad OP (1983) Relaxation of bovine, porcine and human brain arteries by parathyroid hormone. Life Sci 33:2497–2503PubMedCrossRefGoogle Scholar
- 19.Takemae T, Mizukami M, Kin H, Kawase T, Araki G (1978) Computed tomography of ruptured intracranial aneurysms in acute stage – relationship between vasospasm and high density on CT scan [author’s transl]. No To Shinkei (Brain Nerve) 30:861–866Google Scholar
- 20.Vergouwen MD, Ilodigwe D, Macdonald RL (2011) Cerebral infarction after subarachnoid hemorrhage contributes to poor outcome by vasospasm-dependent and -independent effects. Stroke 42:924–929PubMedCrossRefGoogle Scholar
- 21.Vergouwen MD, Vermeulen M, van Gijn J, Rinkel GJ, Wijdicks EF, Muizelaar JP, Mendelow AD, Juvela S, Yonas H, Terbrugge KG, Macdonald RL, Diringer MN, Broderick JP, Dreier JP, Roos YB (2010) Definition of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage as an outcome event in clinical trials and observational studies: proposal of a multidisciplinary research group. Stroke 41:2391–2395PubMedCrossRefGoogle Scholar
- 22.Weir B (1987) Aneurysms affecting the nervous system. Williams & Wilkins, BaltimoreGoogle Scholar
- 23.Weir B, Grace M, Hansen J, Rothberg C (1978) Time course of vasospasm in man. J Neurosurg 48:173–178PubMedCrossRefGoogle Scholar