Tumours of the Pituitary Region

Chapter

Abstract

Those interested in a more detailed account of the history of the development of the treatment of pituitary tumours are referred to the excellent chapter of Professor Landolt [1]. A more succinct account may be found in another chapter by Professor Takakura et al. [2]. For the present purpose it is enough to illustrate the canvas of history with broad brush strokes. Horsley is credited with the first successful craniotomy for a pituitary macroadenoma in 1889 [3]. Cushing famous for his work on pituitary adenomas performed 338 operations of which only 107 were undertaken via a craniotomy approach. It is of perhaps only academic interest but his approach was entirely extradural until the level of the sphenoid ridge was reached [4]. His operative mortality was 6.2% and as late as 1959 Krayenbűhl reported an operative mortality of 8.4% [1]. This persistent high mortality led to increased interest in the use of radiotherapy for the treatment of pituitary Macroadenomas, the symptoms of which were due to mass effects.

Keywords

Tumour Volume Pituitary Adenoma Dopamine Agonist Pituitary Tumour Cavernous Sinus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag/Wien 2011

Authors and Affiliations

  1. 1.BergenNorway

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