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Multicenter Study: How to Pull It Off? The PIVOT Trial

  • Eleonor Svantesson
  • Eric Hamrin Senorski
  • Alicia Oostdyk
  • Yuichi Hoshino
  • Kristian Samuelsson
  • Volker Musahl
Chapter

Abstract

The Prospective International Validation of Outcome Technology (PIVOT) trial was a prospective multicenter study performed between four academic centers: the University of Pittsburgh (Pittsburgh, PA, USA), Istituto Ortopedico Rizzoli (Bologna, Italy), Sahlgrenska University Hospital (Gothenburg, Sweden), and Kobe University (Kobe, Japan). The purpose of the trial was to provide novel in vivo information about the validity of quantitative measurements of the pivot shift test to aid in the assessment of anterior cruciate ligament (ACL) deficiency and the outcome after ACL reconstruction. The present chapter focuses on sharing the experiences of how the PIVOT trial was planned and performed and on presenting some of the outcomes and learning points of the trial.

Keywords

ACL Multicenter Trial Pivot shift Rotatory knee laxity Image analysis technique Inertial sensor 

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Copyright information

© ISAKOS 2019

Authors and Affiliations

  • Eleonor Svantesson
    • 1
  • Eric Hamrin Senorski
    • 2
  • Alicia Oostdyk
    • 3
  • Yuichi Hoshino
    • 4
  • Kristian Samuelsson
    • 1
    • 5
  • Volker Musahl
    • 3
  1. 1.Department of OrthopaedicsInstitute of Clinical Sciences, The Sahlgrenska Academy, University of GothenburgGothenburgSweden
  2. 2.Department of Health and RehabilitationInstitute of Neuroscience and Physiology, The Sahlgrenska Academy, University of GothenburgGothenburgSweden
  3. 3.Department of Orthopaedic SurgeryUniversity of PittsburghPittsburghUSA
  4. 4.Department of Orthopaedic SurgeryKobe UniversityKobeJapan
  5. 5.Department of OrthopaedicsSahlgrenska University HospitalMölndalSweden

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