Advertisement

Mitosis

  • Sarah StaufferEmail author
  • Aaron Gardner
  • Dewi Ayu Kencana Ungu
  • Ainara López-Córdoba
  • Matthias Heim
Chapter

Abstract

In the Mitosis simulation you will be able to dive into the cell cycle to understand how cell division occurs, and learn about its many different stages. You will investigate various cell types using light and fluorescence microscopy to visualize the stages of mitosis and how they are regulated. Finally, using an exciting new compound you will see if you can inhibit or accelerate cell division. How will this affect the survival of the organisms and what are the wider implications for its use?

Further Reading

  1. Alberts B et al (2015) The Molecular Biology of the Cell, 6th edn. Garland Science, AbingdonGoogle Scholar
  2. Besson A, Dowdy SF, Inhibitors RJMCDK (2008) Cell Cycle Regulators and Beyond. Dev Cell 14(2):159–169CrossRefGoogle Scholar
  3. Jordan MA et al (1996) Mitotic Block Induced in HeLa Cells by Low Concentrations of Paclitaxel (Taxol) Results in Abnormal Mitotic Exit and Apoptotic Cell Death. Cancer Res 56(4):816–825PubMedGoogle Scholar
  4. Kastan MB, Bartek J (2004) Cell-cycle checkpoints and cancer. Nature 432: p:316CrossRefGoogle Scholar
  5. OpenStax, Biology. OpenStax CNX. Jun 1, 2018. http://cnx.org/contents/185cbf87-c72e-48f5-b51e-f14f21b5eabd@11.2
  6. Roukos V et al (2015) Cell cycle staging of individual cells by fluorescence microscopy. Nat Protoc 10: p:334CrossRefGoogle Scholar
  7. Urey LA et al (2014) Campbell Biology, 10th edn. Pearson, BostonGoogle Scholar
  8. Wilson CR, Sauer JM, Taxines HSB (2001) a review of the mechanism and toxicity of yew (Taxus spp.) alkaloids. Toxicon 39(2):175–185CrossRefGoogle Scholar

Copyright information

© Labster ApS under license to Springer Verlag GmbH 2018

Authors and Affiliations

  • Sarah Stauffer
    • 1
    Email author
  • Aaron Gardner
    • 1
  • Dewi Ayu Kencana Ungu
    • 1
  • Ainara López-Córdoba
    • 1
  • Matthias Heim
    • 1
  1. 1.Labster Group ApSKøbenhavn KDenmark

Personalised recommendations