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Erkrankungen der Lunge

  • Hans-Joachim Mentzel
  • Meinrad Beer
  • Michael Riccabona

Zusammenfassung

Durch retinierte fetale Lungenflüssigkeit ist die transiente Tachypnoe des Neugeborenen gekennzeichnet. Während der Fetalzeit sind die Lungen mit einer Flüssigkeit gefüllt, die aus einem Ultrafiltrat des fetalen Serums besteht. Zwischen Fruchtwasservolumen und Lungenflüssigkeit besteht ein enger Zusammenhang. Normalerweise wird diese Flüssigkeit während bzw. schon kurz nach der Geburt über das tracheobronchiale System (30 %), die interstitielle Lymphflüssigkeit (30 %) und die Kapillaren (40 %) abtransportiert. Diese physiologische Entfernung von Flüssigkeit aus der Lunge (clearance) ist bei der transienten Tachypnoe verzögert, sodass Amnionflüssigkeit in den Alveolen, im Interstitium, in den Interlobien und im Pleuraspalt verbleibt.

Literatur

  1. ALRAJAB S, YOUSSEF AM, AKKUS NI, CALDITO G. Pleural ultrasonografy versus chest radiografy for the diagnosis of pneumothorax: review of the literature and meta-analysis. Crit Care 2013; 17: R208CrossRefGoogle Scholar
  2. ANADKAT JS, KUZNIEWICZ MW, CHAUDHARI BP, COLE FS, HAMCAS A. Increased risk for respiratory distress among white, male, late preterm and term infants. J Perinatol 2012; 32: 780 785CrossRefGoogle Scholar
  3. ASKENAZI SS, PERLMAN M. Pulmonary hypoplasia: lung weight and radial alveolar count as criteria of diagnosis. Arch Dis Child 1979; 54: 614-618CrossRefGoogle Scholar
  4. AWMF ONLINE. S2K Leitlinie 024-021Google Scholar
  5. Bancalari E, CLAURE N, SOSENKO IR. Bronchopulmonary dysplasia: changes in pathogenesis, epidemiology and definition. Semin Neonatol 2003; 8: 63-71CrossRefGoogle Scholar
  6. BANDO Y, NAKAGAWA M, ITO K, OZAWA Y, SAKURAI K, SHIMOHIRA M, SHIBAMOTO Y. Horseshoe lung associated with left lung hypoplasia: case report and systematic review of the literature. Pol J Radiol 2015; 80: 464-469CrossRefGoogle Scholar
  7. BARALDI E, CARRARO S, FILIPPONE M. Early Hum Dev 2009; 85: S1-3Google Scholar
  8. BERROCAL T, MADRID C, NOVO S, GUTIERREZ J, ARJONILLA A, GOMEZ-LEON N. Congenital anomalies of the tracheobronhchial tree, lung, and mediastinum: embryology, radiology, and pathology. Radiografics 2004; 24: e17. DOI 10.1148/rg.e17]CrossRefGoogle Scholar
  9. BOOTH TN, ALLEN BA, ROYAL SA. Lymphatic air embolism: a new hypothesis regarding the pathogenesis of neonatal systemic air embolism. Pediatr Radiol 1995; 25 Suppl 1: 220-227Google Scholar
  10. CATHO G, GILLET Y, DUMITRESCU O, LINA G, LABBE G, BELLON G, REIX P. Intrafamilial transmssion of staphylococcus aureus Panton-Valentine leukocidin responsible for tw cases of neonatal necrotizing penumonia. Arch Pediatr 2011; 18: 1090-1094Google Scholar
  11. CATTAROSSI L. Early Hum Dev 2013; 89: S17-19Google Scholar
  12. CATTAROSSI L. Lung ultrasound: its role in neonatology and pediatrics. Early Hum Dev 2013; 89: S17-19Google Scholar
  13. CHO MJ, KIM DY, KIM SC, KIM KS, KIM EA, LEE BS. Embolization versus surgical resection of pulmonary sequestration: clinical experiences with a thoracoscopic approach. J Pediatr Surg 2012; 12: 2228-2233CrossRefGoogle Scholar
  14. CLEVELAND RH, WEBER B. Retained fetal lung liquid in congenital lobar emphysema: a possible predictor of polyalveolar lobe. Pediatr Radiol 1993; 23: 291-295CrossRefGoogle Scholar
  15. CLEVELAND RH. A radiological update on medical diseases of the newborn chest. Pediatr Radiol 1995; 25: 631–637CrossRefGoogle Scholar
  16. CLEVELAND RH, Rhein. Newborn Chest. In: Cleveland RH (Ed.). Imaging in Pediatric Pulmonology. Springer. New York 2012Google Scholar
  17. COCLITE E, DI NATALE C, NIGRO G. Congenital and perinatal cytomegalovirus lung infection. J Matern Fetal Neonatal Med 2013; 26: 1671-1675CrossRefGoogle Scholar
  18. CROTTY EJ. Neonatal Chest Imaging. In: Garcia-Pena P, Guillerman RP (Ed). Pediatric Chest Imaging. Springer. Berlin-Heidelberg. 2014. 173-196Google Scholar
  19. DARGAVILLE PA, COPNELL B. Pediatrics 2006; 117: 1712-1721Google Scholar
  20. DONOGHUE V. Hyaline membrane disease and complications of its treatment. In: Donoghue V (Ed.). Radiological Imaging of the Neonatal Chest. Springer Berlin 2002Google Scholar
  21. FISCH D, UHL M, LANGER M. Radiologe 2005; 45: 197-210Google Scholar
  22. GARCIA-PENA P, COMA A, ENRIQUEZ G. Congenital lung malformations: radiological findings and clues for differential diagnosis. Acta Radiol 2013; 54: 1086-1095CrossRefGoogle Scholar
  23. GHIDINI A, SPONG CY. Severe meconium aspiration syndrome is not caused by aspiration of meconium. Am J Obstet Gynecol 2001; 185: 931-938CrossRefGoogle Scholar
  24. GORTNER L, TUTDIBI E. Respiratorische Erkrankujngen bei Früh- und Neugeborenen. Z Geburtsh Neonatol 2011; 215: 145-151Google Scholar
  25. HILES M, CULPAN AM, WATTS C, MUNYOMBWE T, WOLSTENHULME S. Neonatal respiratory distress syndrome: Chest X-ray or lung ultrasound? A systematic review. Ultrasound 2017; 25: 80-91CrossRefGoogle Scholar
  26. HOEPKER A, SEEAR M, PETROCHEILOU A, HAYES D, NAIR A, DEODHAR J, KADAM S, O’TOOLE J. Wilson-Mikity syndrome: updated diagnostic criteria based on nine cases and a review oft he literature. Pediatr Pulmonol 2008; 43: 1004-1012CrossRefGoogle Scholar
  27. HOOVEN TA, POLIN RA. Pneumonia. Semin Fetal Neonatal Med 2017; 22: 206–213Google Scholar
  28. JANSSEN DJ, CARNIELLI VP, COGO P, BOHLIN K, HAMVAS A, LUIJENDIJK IH, BUNT JE, TIBBOEL , ZIMMERMANN LJ. Surfactant phosphatdiylcholine metabolism in neonates with meconuium aspiration syndrome. J Pediatr 2006; 149: 634-639Google Scholar
  29. JOBE A, BANCLARI E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med 2001; 163: 1723–1729CrossRefGoogle Scholar
  30. KO SF, NG SH, LEE TY, WAN YL, LIANG CD, LIN JW, CHEN WJ, HSIEH MJ. Noninvasive imaging of bronchopulmonary sequestration. Am J Roentgenol 2000; 175: 1005-1012CrossRefGoogle Scholar
  31. KUNISAKI SM, BARNEWOLT CE, ESTROFF JA, MYERS LB, BULICH LA, WONG G, LEVINE D, WILKINS-HAUG LE, BENSON CB, JENNINGS RW. Large fetal congenital cystic adenomatoid malformatins: growth trends and patient survival. J Pediatr Surg 2007; 42: 404-410Google Scholar
  32. LEE EY, DORKIN H, VARGAS SO. Congenital pulmonary malformations in pediatric patients: review and update on etiology, classification, and imaging findings. Radiol Clin North Am 2011; 49: 921-948CrossRefGoogle Scholar
  33. LICHTENSTEIN D et al. Am J Respir Crit Care Med 1997; 156: 1640-1646CrossRefGoogle Scholar
  34. LIECHTY KW, FLAKE AW. Pulmonary vascular malformations. Sem Ped Surg 2008; 9-16CrossRefGoogle Scholar
  35. MANSON D. Diagnostic Imaging of Neonatal Pneumonia. In: Donoghue V (Ed.). Radiological Imaging of the Neonatal Chest. Springer Berlin 2002Google Scholar
  36. MARANELLA E, CONTE E, DI NATALE C, COCLITE E, DI FABIO S. Disseminated, large-sized neonatal pneumatoceles: the wait-and-see strategy. Pediatr Pulmonol 2014; 49: E69-71CrossRefGoogle Scholar
  37. MATA JM, CASTELLOTE A. Pulmonary malformations beyond the neonatal period. In: Pediatric Chest Imaging. Garcia-Pena P, Guillerman RP (Ed.) Springer 2014; 197-217Google Scholar
  38. MAY C, PRENDERGAST M, SALMAN S, RAFFERTY GF, GREENOUGH A. Chest radiografy thoracic areas and lung volumes in infants developing bronchopulmonary dysplasis. Pediatr Pulmonol 2009; 44: 80-85CrossRefGoogle Scholar
  39. MILNER AD, SAUNDERS RA, HOPKIN IE;. Effects of delivery by caesarean section on lung mechanics and lung volume in the human neonate. Arch Dis Child 1978; 53: 545 – 548, ATASY B, ERGUN H, OKUKUL E et al J Matern Fetal Neonatal Med 2013Google Scholar
  40. NEWMAN B, GONDOR M. MR Evaluation of right pulmonary agenesis and vascular airway compression in pediatric patients. AJR 1997; 168: 55-58CrossRefGoogle Scholar
  41. NEWMAN B. Imaging of medical disease in the newborn lung. Radiol Clin North Am 1999; 37: 1049-1065Google Scholar
  42. NOONAN JA, WALTERS LR, REEVES JT. Congenital pulmonary lymphangiectasis. Am J Dis Child 1970; 120: 314CrossRefGoogle Scholar
  43. NORTHWAY WH, ROSAN RC, PORTER DY. Pulmonary disease following respiratory therapy of hyaline-membrane disease. N Engl J Med 1967; 276: 357-368CrossRefGoogle Scholar
  44. NORTHWAY WH, ROSAN RC. Radiografic features of pulmonary oxygen toxicity in the newborn: bronchopulmonary dysplasia. Radiology 1968; 91: 49-58Google Scholar
  45. OWENS CM. Meconium aspiration. In: Radiological imaging of the neonatal chest. DONOGHUE V. Springer 2002; 49-61Google Scholar
  46. PARAPPIL H, MASUD f, SALAMA H, RAHMAN S. BMJ Case Rep 2015. Doi: 10.1136/bcr-2014-208743Google Scholar
  47. PRIEST JR, WILLIAMS GM, HILL DA, DEHNER LP, JAFFÉ A. Pulmonary cysts in early childhood and the risk of malignancy. Pediatr Pulmonol 2009; 44: 14-30CrossRefGoogle Scholar
  48. PUIG S, HÖRMANN M, KUHLE S, RAND T, REBHANDL W, SCHAEFER-PROKOP C, POHNHOLD W. Chest X-ray of the neonate. Radiologe 2000; 40: 3-51Google Scholar
  49. REITERER F, GROSSAUER K, MORRIS N, UHRIG S, RESCH B. Congenital pulmonary lymphangiectasis. Paediatr Resp Rev 2014; 15: 275-280CrossRefGoogle Scholar
  50. REUTER S, MOSER C, BAACK M. Respiratory distress in the newborn. Pediatr Rev 2014; 35: 417-428CrossRefGoogle Scholar
  51. RÜDIGER M. Bronchopulmonale Dysplasie. In: JORCH G, HÜBLER A. Neonatologie. Die Medizin des Früh- und Reifgeborenen. Thieme Stuttgart New York 2010; 175-180Google Scholar
  52. SACCONE G, BERGHELLA V. BMJ 2016; 12: 355: i5044]Google Scholar
  53. SAUVET F, MICHEL JL, BENACHI A et al. Management of asymptomatic neonatal cystic adenomatoid malformations. J Pediatr Surg 2003; 38: 548-552Google Scholar
  54. SCHULZE A. Mekoniumaspiration. In: Neonatologie. Die Medizin des Früh- und Reifgeborenen. Thieme 2010; 195-197Google Scholar
  55. SOTIRIADIS A, MAKRYDIMAS G, PAPATHEODOROU S, IOANNIDIS JPl Corticosteroids for preventing neonatal respiratory morbidity after elective caesarean section at term. Cochrane Database Syst Rev 2009; (4) CD006614Google Scholar
  56. STAATZ G. Thoraxbildgebung beim Kind. In: RICCABONA M. Trainer Kinderadiologie. Thieme 2010; 45 46, van MASTRIGT E et al. Pediatr Pulmonol 2016; 51: 975-986Google Scholar
  57. STERN EJ, WEBB WR, WARNOCK ML, SALMON CJ. Bronchopulmonary sequestration: dynamic, ultrafast, high-resolution CT evidence o fair trapping. Am J Roentgenol 2000; 74: 235-241Google Scholar
  58. STOCKER JT, MADEWELL JE, DRAKE RM. Congenital cystic adenomatoid malformation of the lung. Classification and morphologic spectrum. Hum Pathol. 1977; 8: 155-171CrossRefGoogle Scholar
  59. STOCKER JT. Congenital pulmonary airway malformation: a new name and an expanded classification of congenital cystic adenomatoid malformation of the lung. Histopathology 2002; 41: 424-431Google Scholar
  60. STOLL BJ, HANSEN N, BELL EF,SHANKARAN S, LAPTOOK AR, WALSH MC, HALE EC, NEWMAN NS, SCHIBLER K, CARLO WA et al. Neonatal outcomes of extremely preterm infants from the NICHD neonatal research network. Pediatrics 2010; 126: 443-456]CrossRefGoogle Scholar
  61. STOLL BJ, HANSEN NI, HIGGINS RD. Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network. 2002–2003. Pediatr Infect Dis J 2005; 24: 635-639CrossRefGoogle Scholar
  62. SWARNAM K, SORAISHAM AS, SIVANANDAN S. Advances in the management of meconium aspiration syndrome. Int J Pediatr 2012; 2012: 359371Google Scholar
  63. SWISCHUK LE, SHETTY BP, JOHN SD. The lungs in immature infants: how important is surfactant therapy in preventing chronic lung problems? Pediatr Radiol 1996; 26: 508–511]CrossRefGoogle Scholar
  64. TUTDIBI E, GRIES K, BÜCHELER M, MISSELWITZ B, SCHLOSSER RL, GORTNER. Impact of labor on outcomes in transient tachypnea of the newborn: population-based staudy. Pediatrics 2010; 125: e577-583CrossRefGoogle Scholar
  65. VERGINE M, COPETTI R, BRUSA G, CATAROSSI L. Lung ultrasound accuracy in respiratory distress syndrome and transient tachypnea of the newborn. Neonatology 2014; 106: 87-93CrossRefGoogle Scholar
  66. WASILEWSKA E, LEE E, EISENBERG RL. Unilateral hyperlucent lung in children. AJR 2012; 198: 400-404CrossRefGoogle Scholar
  67. WEINSTEIN MR et al. Pediatr Pulmonol 1994; 18: 284 – 289; FISCH D, UHL M, LANGER M. Radiologe 2005; 45: 197-210Google Scholar
  68. WINTERS WD, EFFMANN EL. Congenital masses of the lung: prenatal and postnatal imaging evaluation. J Thorac Imaging 2001; 16: 196-206CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature 2018

Authors and Affiliations

  1. 1.Sektion KinderradiologieUniversitätsklinikum JenaJenaDeutschland
  2. 2.Klinik für Diagnostische und Interventionelle RadiologieUniversitätsklinikum UlmUlmDeutschland
  3. 3.Klinische Abteilung für KinderradiologieUniversitätsklinik für Radiologie, LKH-Univ. Klinikum GrazGrazÖsterreich

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