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Malignancy in Orthopedics

  • Stefano Fanti
  • Mohsen Farsad
  • Luigi Mansi
  • Paolo Castellucci
Chapter

Abstract

Bone and soft-tissue sarcomas are relatively rare conditions since they represent about 1% of all cancers. Unfortunately, the mortality rate is very high since the 5-year survival rate is about 50%; however prognosis is strongly correlated with the histopathological tumor grade. Treatments include surgery, neoadjuvant and adjuvant chemotherapy, and radiotherapy. The diagnostic flowchart includes planar X-rays, bone scan, CT, and MRI. MRI should be considered the imaging of choice due to the high soft-tissue contrast and the high accuracy in the detection of soft tissue and bone involvement [1]. It is possible that in the next future this could be one of the principal applications of the hybrid PET/MRI tomography.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Stefano Fanti
    • 1
  • Mohsen Farsad
    • 2
  • Luigi Mansi
    • 3
  • Paolo Castellucci
    • 4
  1. 1.Metropolitan Nuclear Medicine of BolognaUniversity of BolognaBolognaItaly
  2. 2.Nuclear Medicine DepartmentCentral Hospital BolzanoBolzanoItaly
  3. 3.Section Health and Development, Interuniversity Research Center for Sustainability (CIRPS)NaplesItaly
  4. 4.Metropolitan Nuclear MedicineAOU S.Orsola-Malpighi HospitalBolognaItaly

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