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Die Plazenta pp 119-133 | Cite as

Die Effekte von legalen und illegalen Drogen auf die Plazentafunktion

  • Justine Fitzgerald
  • Ekkehard Schleußner
Chapter

Zusammenfassung

Für die meisten Schwangeren ist die Schwangerschaft eine besondere Lebensphase, in der sie sich verantwortungsvoll dafür entscheiden, alles zu tun, was eine optimale Entwicklung des Ungeborenen ermöglicht, insbesondere, in dem sie aufhören zu rauchen und Alkohol zu trinken oder aber auch auf Drogenkonsum verzichten. Für die überwiegende Mehrheit ist jeglicher Drogengenuss obsolet, doch für eine leider nicht abnehmende Minderheit gilt dies nicht. Belastbare deutsche Daten gibt es nicht, für die USA wird von einer konstanten Zahl von 5,9 % Schwangeren mit illegalem Drogenkonsum berichtet. Eine pränatale Drogenexposition birgt eine Vielzahl von Risiken für Mutter und Kind, die zu geburtshilflichen und neonatalen Komplikationen führen können. Die häufigsten Probleme entstehen aufgrund von Störungen der Plazentafunktion: fetale Wachstumsrestriktion, Präeklampsie, Frühgeburtlichkeit, ein vorzeitiger Blasensprung bis hin zur vorzeitigen Plazentalösung und intrauterinem Fruchttod. In diesem Kapitel werden die plazentaassoziierten Effekte der wichtigsten legalen und illegalen Drogen und mögliche Pathomechanismen in der Plazenta beschrieben.

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Copyright information

© Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature 2018

Authors and Affiliations

  • Justine Fitzgerald
    • 1
  • Ekkehard Schleußner
    • 2
  1. 1.Zentrum für ambulante Medizin IUniversitätsklinikum JenaEisenbergDeutschland
  2. 2.Klinik für GeburtsmedizinFriedrich Schiller Universität, Universitätsklinikum JenaJenaDeutschland

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