Hautersatz – Tissue Engineering

  • Thomas Biedermann
  • Ernst Reichmann
  • Clemens Schiestl
Chapter

Zusammenfassung

Dieses Kapitel beschäftigt sich mit der Herstellung, Untersuchung und klinischen Anwendung von künstlichen Ersatzstoffen für Haut sowie ex vivo erzeugter menschlicher Haut. Es erfolgt ein historischer Abriss der Entwicklung von Ersatzmaterialien und zellulärem Hautersatz für spezifische Schichten der Haut und gibt einen Überblick über ihre heutige Anwendung. Dazu werden klinische Fallbeispiele für die Anwendungen präsentiert, die positiven Seiten, aber auch die Problematik der jeweiligen Therapie aufgezeigt. Weiterhin wird der neueste Forschungsstand zur Verbesserung und Weiterentwicklung von tissue-engineertem Hautersatz dargelegt. Außerdem wird ein Einblick in die regulatorischen Anforderungen hinsichtlich der Zulassung und Herstellung von Zellprodukten für eine klinische Anwendung gegeben.

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Copyright information

© Springer-Verlag GmbH Deutschland 2017

Authors and Affiliations

  • Thomas Biedermann
    • 1
  • Ernst Reichmann
    • 1
  • Clemens Schiestl
    • 2
  1. 1.Tissue Biology Research Unit, Chirurgische KlinikUniversitäts-KinderspitalZürichSchweiz
  2. 2.Zentrum für brandverletzte Kinder, Plastische und Rekonstruktive Chirurgie, Zentrum Kinderhaut, Chirurgische KlinikUniversitäts-KinderspitalZürichSchweiz

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