• Hélder PereiraEmail author
  • Ibrahim Fatih Cengiz
  • Joana Silva-Correia
  • Maggali Cucciarini
  • Pablo E. Gelber
  • Joao Espregueira-Mendes
  • Joaquim Miguel Oliveira
  • Rui Luís Reis


The menisci are nonuniform and heterogeneous structures with segmental variations according to its biology and function. It is a fibrocartilaginous tissue that plays a central role on the joint kinematics. However, they are also the most frequently injured structures of the human knee. In the advent of new technologies including tissue engineering and regenerative medicine, it is critical to deeper understand its ultrastructure and physiological function aiming to find ways for not only to enhance the repair and/or replacement approached but also to develop novel regenerative strategies. Herein, the presented work aims to describe the most relevant anatomic and biologic features of the meniscus.


Biomechanics Biology Cells Extracellular matrix Growth factors Meniscus Tissue engineering Vascularity 


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Copyright information

© ESSKA 2016

Authors and Affiliations

  • Hélder Pereira
    • 1
    • 2
    • 3
    • 4
    Email author
  • Ibrahim Fatih Cengiz
    • 1
    • 2
  • Joana Silva-Correia
    • 1
    • 2
  • Maggali Cucciarini
    • 5
  • Pablo E. Gelber
    • 6
    • 7
  • Joao Espregueira-Mendes
    • 1
    • 2
    • 8
  • Joaquim Miguel Oliveira
    • 1
    • 2
  • Rui Luís Reis
    • 1
    • 2
  1. 1.Orthopedic DepartmentCentro Hospitalar Póvoa de Varzim - Vila do CondeVila do CondePortugal
  2. 2.3B’s Research Group – Biomaterials, Biodegradables and BiomimeticsUniv. Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineGuimarãesPortugal
  3. 3.ICVS/3B’s – PT Government Associated LaboratoryBragaPortugal
  4. 4.Ripoll y De Prado Sports Clinic FIFA Medical Centre of ExcellenceMurcia-MadridSpain
  5. 5.Center of Experimental OrthopaedicsSaarland University Medical CenterHomburgGermany
  6. 6.Department of Orthopaedic SurgeryHospital de la Santa Creu i Sant PauBarcelonaSpain
  7. 7.ICATME– Hospital Universitari Quirón DexeusBarcelonaSpain
  8. 8.Clínica do Dragão , Espregueira-Mendes Sports Centre & FIFA Medical Centre of ExcellencePortoPortugal

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