Computer-Aided Diagnostics and Pattern Recognition: Automated Glaucoma Detection

  • Thomas Köhler
  • Rüdiger Bock
  • Joachim Hornegger
  • Georg Michelson


Glaucoma is one of the major causes for blindness with a high rate of unreported cases. To reduce this number, screening programs are performed. However, these are characterized by a high workload for manual and cost-intensive assessment. Computer-aided diagnostics (CAD) to perform an automated pre-exclusion of normals might help to improve program’s efficiency.

This chapter reviews and discusses recent advances in the development of pattern recognition algorithms for automated glaucoma detection based on structural retinal image data. Two main methodologies for glaucoma detection are introduced: (i) structure-driven approaches that mainly rely on the automated extraction of specific medically relevant indicators and (ii) data-driven techniques that perform a generic machine learning approach on entire image data blobs. Both approaches show a reasonable and comparable performance although they rely on different basic assumptions. A combination of these might further improve CAD for a more efficient and cost-sensitive workflow as a major proportion of normals will be excluded from unnecessary detailed investigations.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Thomas Köhler
    • 1
    • 2
  • Rüdiger Bock
    • 1
    • 2
  • Joachim Hornegger
    • 1
    • 2
  • Georg Michelson
    • 3
    • 4
  1. 1.Pattern Recognition Lab, Department of Computer ScienceFriedrich-Alexander-Universität Erlangen-NürnbergErlangen, BavariaGermany
  2. 2.Erlangen Graduate School in Advanced Optical Technologies (SAOT)Erlangen, BavariaGermany
  3. 3.Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen Graduate School in Advanced Optical Technologies (SAOT)Erlangen, BavariaGermany
  4. 4.Department of OphthalmologyInterdisciplinary Center of Ophthalmic Preventive Medicine and Imaging, Friedrich-Alexander-Universität Erlangen-NürnbergErlangen, BavariaGermany

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