Biosynthesis pp 254-267 | Cite as

Polymyxins

  • Henry Paulus
Chapter
Part of the Antibiotics book series (ANTIBIOTICS)

Abstract

The polymyxin group of antibiotics includes the closely related peptides polymyxin A (Ainsworth et al., 1947), polymyxin B1 and B2 (Brownlee and Jones, 1948), polymyxin C (Brownlee and Jones, 1948), polymyxin D (Benedict and Langlykke, 1947; Stansly et al.,1947), polymyxin E1 and E2 (Brown-Lee and Jones, 1948; Koyama, 1952), polymyxin M (Ilyinskaya and Rossovskaya, 1958; Khoklov et al., 1960), and circulin A and B (Murray et al., 1949). Polymyxin A was originally named aerosporin, and the antibiotic colistin (also called colimycin) is now known to be identical with polymyxin E. Polymyxins A, C and D have not been well characterized and may represent mixtures of substances.

Keywords

Culture Fluid Antibiotic Production Bacillus Polymyxa Antibiotic Synthesis Antibiotic Formation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© Springer-Verlag Berlin Heidelberg 1967

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  • Henry Paulus

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