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Predictive Assays: Animal and Man, and In Vitro and In Vivo

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Textbook of Contact Dermatitis

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Abstract

Assuming that data from predictive tests are interpreted prudently by dermatotoxicologists with extensive training in quantitative structure-activity relationships, animal and human predictive assays combined with broad clinical experience should aid rational risk-benefit decision making.

Adapted from E. Patrick and H. Maibach (1989) Dermatotoxicology: In: A. Wallace Hayes (ed.) Principles and Methods of Toxicology, 2nd edn. Raven Press, New York, Chap. 13.

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Authors
  1. Esther Patrick
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  2. Howard I. Maibach
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Editor information

Editors and Affiliations

  1. Contact Dermatitis Clinic, St. John’s Dermatology Centre, St. Thomas’s Hospital, Lambeth Palace RD, SE1 7 EH, London, UK

    Richard J. G. Rycroft

  2. Department of Dermatology, Gentofte Hospital University of Copenhagen, Niels Andersens Vej 65, 2900, Hellerup, Denmark

    Torkil Menné

  3. Hautklinik der Städtischen Kliniken Dortmund, Abteilung Dermatologie, Universität Witten/Herdecke, Beurhausstraße 40, 4600, Dortmund, Germany

    Peter J. Frosch

  4. Laboratoire de Dermatochimie, Université Louis Pasteur, Clinique Dermatologique, 1 Place de l’Hôpital, 67091, Strasbourg Cedex, France

    Claude Benezra

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© 1992 Springer-Verlag Berlin Heidelberg

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Patrick, E., Maibach, H.I. (1992). Predictive Assays: Animal and Man, and In Vitro and In Vivo. In: Rycroft, R.J.G., Menné, T., Frosch, P.J., Benezra, C. (eds) Textbook of Contact Dermatitis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-13119-0_34

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  • DOI: https://doi.org/10.1007/978-3-662-13119-0_34

  • Publisher Name: Springer, Berlin, Heidelberg

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  • Online ISBN: 978-3-662-13119-0

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