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Production of Artemisinin from in Vitro Cultures of Artemisia annua L.

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Book cover Medicinal and Aromatic Plants XII

Part of the book series: Biotechnology in Agriculture and Forestry ((AGRICULTURE,volume 51))

Abstract

Malaria, one of the oldest known diseases, was referred to in Egyptian writings of the 16th century B.C. In the 17th century, Italians believed that breathing bad air (mal aria) arising from swamps was responsible for the disease, and the term malaria first entered the English medical literature in the first half of the 19th century. Each year, this disease afflicts over 300 million people worldwide, killing up to 2.7 million, mostly children. Most of these cases occur in Africa, but large areas of Asia, Central, and South America have high incidences of the disease (Nussenzweig and Long 1994). Out of 37 countries and territories, which are members of the Pan American Health Organization (PAHO), World Health Organization (WHO), 21 still have active malaria transmission (PAHO/WHO 1998).

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Author information

Authors and Affiliations

  1. Department of Plant Biology, Southern Illinois University-Carbondale, Carbondale, Illinois, 62901-6509, USA

    Jorge F. S. Ferreira

  2. Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, Indiana, 47907-1165, USA

    Jules Janick

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  1. Jorge F. S. Ferreira
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  2. Jules Janick
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Editors and Affiliations

  1. Graduate School of Science, Department of Biological Sciences, University of Tokyo, 7-3-1 Hongo, 113-0033, Bunkyo-ku, Tokyo, Japan

    Toshiyuki Nagata

  2. Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, 113-0033, Bunkyo-ku, Tokyo, Japan

    Yutaka Ebizuka

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Ferreira, J.F.S., Janick, J. (2002). Production of Artemisinin from in Vitro Cultures of Artemisia annua L.. In: Nagata, T., Ebizuka, Y. (eds) Medicinal and Aromatic Plants XII. Biotechnology in Agriculture and Forestry, vol 51. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08616-2_1

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  • DOI: https://doi.org/10.1007/978-3-662-08616-2_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-07503-2

  • Online ISBN: 978-3-662-08616-2

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