Zusammenfassung
In der frauenärztlichen Praxis ist es eine der wichtigsten ärztlichen Aufgaben, Frauen und Männer über geeignete Methoden der Empfängnisverhütung und Geburtenkontrolle zu informieren. Im Bewußtsein außerordentlich hoher empfängnisverhütender Sicherheit hormonaler Kontrazeptiva, speziell der oralen Formen, wird leicht übersehen, daß es sich bei diesen Formen der Empfängnisverhütung um hochwirksame pharmakologische Substanzen handelt, die wie alle wirksamen Substanzen unerwünschte Arzneiwirkungen aurweisen können. Die Entwicklung möglichst niedrigdosierter Formen der hormonalen Kontrazeption entspricht nicht nur dem ärztlichen Wunsch, schwerwiegende Begleiterscheinungen (z. B. Thrombosen) soweit wie möglich zu vermeiden, sondern auch dem heutigen Trend der Anwenderinnen, subjektive und objektivierbare Beschwerden nicht mehr zu akzeptieren. Daneben hat man gelernt, eine Reihe erwünschter Nebenwirkungen hormonaler Kontrazeptiva therapeutisch oder prophylaktisch zu nutzen (s. Kap. 21.6).
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Literatur
- Adams MR, Clarkson TB, Shively CA, Parks JS, Kaplan JR (1990) Oral contraceptives, lipoproteins and atherosclerosis. Am J Obstet Gynecol 163:1388PubMedCrossRefGoogle Scholar
- Aktories K, Krog W, Dericks-Tan E, Jiirgensen O, Taubert HD (1976) Die Beeinflussung des Ovarialzyklus durch verschiedene Typen hormonaler Kontrazeptiva. Geburtshilfe Frau-enheilkd 36:318Google Scholar
- Andersson K, Odlind V, Rybo G (1994) Levonorgestrel-relea-sing and copper-releasing (Nova T) IUDs during five years of use: A randomized comparative trial. Contraception 49: 56PubMedCrossRefGoogle Scholar
- Anon A (1992) Does infection occur with modern intrauterine devices? Lancet 339: 783CrossRefGoogle Scholar
- Aref I, Hefnawi F, Kandil O (1973 a) Changes in human ovaries after longterm administration of microdose progestogens. Contraception 7: 503CrossRefGoogle Scholar
- Aref I, Hefnawi F, Kandil O, Abdel Aziz MT (1973 b) Effect of minipills on physiologic responses of human cervical mucus, endometrium, and ovary. Fertil Steril 24: 578PubMedGoogle Scholar
- Asherson RA, Harris NE, Gharavi AE, Hughes GR (1986) Systemic lupus erythematosus, antiphospholipid antibodies, chorea, and oral contraceptives. Arthritis Rheum 29:1535PubMedCrossRefGoogle Scholar
- Astedt B (1971) Low fibrinolytic activity of veins during treatment with ethinylestradiol. Acta Obstet Gynecol Scand 50:279PubMedCrossRefGoogle Scholar
- Aufdemorte TB, Sheridan PJ (1981) Nuclear uptake of sex steroids in gingiva of the baboon. J Periodontol 52: 430PubMedCrossRefGoogle Scholar
- Bäckström T (1983) Premenstrual tension syndrome. In: Bar-din CW, Milgröm E, Mauvais-Jarvis P (eds) Progesteron and progestins. Raven, New York, p 203Google Scholar
- Bain C, Hennekens CH, Speizer FE, Rosner B, Willett W, Belanger C (1982) Oral contraceptive use and malignant melanoma. JNCI 68: 537PubMedGoogle Scholar
- Barbosa I, Bakos O, Olsson SE, Ohlind V, Johansson EDB (1990) Ovarian function during use of a Levonorgestrel-releasing IUD. Contraception 42: 51PubMedCrossRefGoogle Scholar
- Bässler R, Kind M (1989) Pathologie, Systematik und Klassifizierung gutartiger Brusterkrankungen. Gynäkologe 22: 216PubMedGoogle Scholar
- Basu J, Vermund SH, Mikhail M, Palan PR, Romney SL (1989) Plasma reduced and total ascorbic acid in healthy women: effects of smoking and oral contraception. Contraception 39:85PubMedCrossRefGoogle Scholar
- Beck P (1977) Effect of progestins on glucose and lipid metabolism. Ann NY Acad Sci 286: 434PubMedCrossRefGoogle Scholar
- Benson MD, Rebar WR (1986) Relationship of migraine headache and stroke to oral contraceptive use. J Reprod Med 31: 1082PubMedGoogle Scholar
- Beral V, Ramcharan S, Faris R (1977) Malignant melanoma and oral contraceptive use among women in California. Br J Cancer 36: 804PubMedCrossRefGoogle Scholar
- Bettendorf G (1974) Wirkung hormonaler Ovulationshemmer auf die Haut. Kosmetologie 4:150Google Scholar
- Bork K, Bräuninger W, Czarnetzki BM, Addicks B, Paul E, Glitsch M, Noack C (1985) Schwangerschaft nach malignem Melanom. Dtsch Med Wochenschr 110:1323PubMedCrossRefGoogle Scholar
- Böttiger LE, Boman G, Eklund G, Westerholm B (1980) Oral contraceptives and thromboembolic disease: effects of lowering oestrogen content. Lancet 1:1097PubMedCrossRefGoogle Scholar
- Boston Collaborative Drug Surveillance Programme (1973) Oral contraceptives and venous thromboembolic disease, surgically confirmed gallbladder disease, and breast tumors. Lancet 1:1399Google Scholar
- Breckwoldt M (1990) Stellungnahme der Arbeitsgemeinschaft für gynäkologische Endokrinologie. Niedrig dosierte Kontrazeptiva und Thromoboembolierisiko. Frauenarzt 31: 329Google Scholar
- Breckwoldt M, Zahradnik HP (1987) Pathophysiologie der Dysmenorrhoe. In: Mall-Haefeli M (Hrsg) Wirkung kontrazeptiver Steroide. Mit Unterstützung durch Organon, Oberschleißheim, S 7Google Scholar
- Brooks PG (1984) Pill formulations and their effect on lipid and carbohydrate metabolism. J Reprod Med 29 (Suppl): 539PubMedGoogle Scholar
- Buehring GC (1988) Oral contraceptives and breast cancer: what has 20 years of research shown? Biomed Pharmacother 42: 525PubMedGoogle Scholar
- Casagrande JT, Pike MC, Ross RK, Louie EW, Roy S, Henderson BE (1979) „Incessant ovulation” and ovarian cancer. Lancet July 28:170CrossRefGoogle Scholar
- The Centers for Disease Control Cancer and Steroid Hormone Study (1983a) Longterm oral contraceptive use and the risk of breast cancer. JAMA 249:1591CrossRefGoogle Scholar
- The Centers for Disease Control Cancer and Steroid Hormone Study (1983b) Oral contraceptive use and the risk of ovarian cancer. JAMA 249:1596CrossRefGoogle Scholar
- The Centers for Disease Control Cancer and Steroid Hormone Study (1983c) Oral contraceptive use and the risk of endometrial cancer. JAMA 249:1600CrossRefGoogle Scholar
- The Centers for Disease Control Cancer and Steroid Hormone Study and the National Institute of Child Health and Human Development (1986) Oral contraceptive use and the risk of breast cancer. N Engl J Med 315: 405CrossRefGoogle Scholar
- Clarke EA, Hatcher J, McKeown-Eyssen GE, Lickrish GM (1985) Cervical dysplasia: association with sexual behavior, smoking and oral contraceptive use? Am J Obstet Gynecol 151:612PubMedGoogle Scholar
- Conell EB, Kelman CD (1968) Ophthalmologic findings with oral contraceptives. Obstet Gynecol 31: 456Google Scholar
- Cramer DW, Goldman MB, Schiff I et al. (1987) The relationship of tubal infertility to barrier method and oral contraceptives use. JAMA 257: 2446PubMedCrossRefGoogle Scholar
- Croft P, Hannaford PC (1989) Risk factors for acute myocardial infarction in women: evidence from the Royal College of General Practitioners oral contraception study. Br Med J 298:165CrossRefGoogle Scholar
- Cuckle HS, Wald NJ (1982) Evidence against oral contraceptives as a cause of neural tube defects. Br J Obstet Gynaecol 89:547PubMedCrossRefGoogle Scholar
- De Pirro R, Forte F, Bertoli A, Greco AV, Lauro R (1981) Changes in insulin receptors during oral contraception. J Clin Endocrinol Metab 52: 29PubMedCrossRefGoogle Scholar
- De Stefano F, Peterson HB, Ory HW, Layde PM (1982) Oral contraceptives and postoperative venous thrombosis. Am J Obstet Gynecol 143: 227Google Scholar
- Dericks-Tan JSE, Taubert HD (1976) Elevation of serum prolactin during application of oral contraceptives. Contraception 14:1PubMedCrossRefGoogle Scholar
- Dericks-Tan JSE, Schneider K, Taubert HD (1980) The mechanism of action of a new low-dosed combined oral contraceptive. Arch Gynäkol 229:107Google Scholar
- Diamond MP, Greene JW, Thrompson JM, Hooydonk van JE, Wentz AC (1985) Interaction of anticonvulsants and oral contraceptives in epileptic adolescents. Contraception 31: 623PubMedCrossRefGoogle Scholar
- Diddle AW, Gardner WH, Williamson PJ (1969) Oral contraceptive medications and headache. Am J Obstet Gynecol 105:507PubMedGoogle Scholar
- Döring GK, Kauka E, Netzer A (1976) Schwangerschaftsverlauf und Zustand der Kinder nach Anwendung von Ovulationshemmern. Geburtshilfe Frauenheilkd 36:57PubMedGoogle Scholar
- Dreyer NA, Pizzo SV (1980) Blood coagulation and idiopathic thromboembolism among fertile women. Contraception 22: 123PubMedCrossRefGoogle Scholar
- Durber SM, Lawson J, Daly JR (1976) The effect of oral contraceptives on plasma Cortisol and Cortisol binding capacity throughout the menstrual cycle in normal women. Br J Obstet Gynaecol 83: 814PubMedCrossRefGoogle Scholar
- Ebeling K, Nischan P, Schindler C (1987) Use of oral contraceptives and risk of invasive cervical cancer in previously screened women. Int J Cancer 39: 427PubMedCrossRefGoogle Scholar
- Eddy G, Schlaerth JB, Nalick RH, Gaddis O Jr, Nakamura RM, Morrow CP (1983) Postmolar trophoblastic disease in women using hormonal contraception with and without estrogen. Obstet Gynecol 62: 736PubMedGoogle Scholar
- Eichhorn KH, Carol W, Heine A, Klinger G (1975) Beitrag zum Nachweis der Unbedenklichkeit hormonaler Kontrazeptiva auf nachfolgende Schwangerschaften. Zentralbl Gynäkol 97: 481Google Scholar
- El-Mahgoub S, Karim M, Ammar R (1972) Longterm effects of injectable progestogens on the morphology of the human oviducts. J Reprod Med 8: 288PubMedGoogle Scholar
- Elstein M, Morris SE, Groom GV, Jenner DA, Scarisbrick JJ, Cameron EHD (1976) Studies on low dose oral contraceptives: cervical mucus and plasma hormone changes in relation to circulating d-norgestrel and 17α-ethinyl estradiol concentrations. Fertil Steril 27: 892PubMedGoogle Scholar
- Engel HJ, Engel E, Behnke K, Lichtlen P (1987) Angiographische Befunde nach Herzinfarkt junger Frauen: die Rolle oraler Kontrazeptiva. Herz 12: 290PubMedGoogle Scholar
- Eschenbach DA, Harnisch JP, Holmes KK (1977) Pathogenesis of acute pelvic inflammatory disease: role of contraception and other risk factors. Am J Obstet Gynecol 128: 838PubMedGoogle Scholar
- Fasal E, Paffenbarger RS (1975) Oral contraceptives as related to cancer and benign lesions of the breast. J Natl Cancer Inst 55: 767PubMedGoogle Scholar
- Fasoli M, Parazzini F, Ceccetti G, La Vecchia C (1989) Postcoital contraception: an overview of published studies. Contraception 39: 459PubMedCrossRefGoogle Scholar
- Fisch IR, Frank J (1977) Oral contraceptives and blood pressure. JAMA 237: 2499PubMedCrossRefGoogle Scholar
- Fisch IR, Freedman SH, Myatt AV (1972) Oral contraceptives, pregnancy, and blood pressure. JAMA 222:1507PubMedCrossRefGoogle Scholar
- Fischer RI, Neifeld JP, Lippman ME (1976) Oestrogen receptors in human malignant melanoma. Lancet August 14:337CrossRefGoogle Scholar
- Fournier von D, Junkermann H, Krapfl E, Anton HW, Stolz W, Heep J (1989) überblick über Therapieformen gutartiger Brusterkrankungen. Gynäkologe 22: 246Google Scholar
- Franceschi S, La Vecchia C, Parazzini F et al. (1984) Oral contraceptives and benign breast disease: a case-control study. Am J Obstet Gynecol 149: 602PubMedGoogle Scholar
- Fraser IS, Jansen RPS (1983) Why do inadvertent pregnancies occur in oral contraceptive users. Contraception 27: 531PubMedCrossRefGoogle Scholar
- Freundl G, Brossmann H (1985) Ovulationshemmer und Tumoren. Dtsch Med Wochenschr 110:1346PubMedCrossRefGoogle Scholar
- Frick V (1978) Störfaktor Sicherheit. Sexualmedizin 3: 221Google Scholar
- Gabius S, Blossey TH, Teichmann AT, Nagel GA (1988) Sind östrogene beim Mammakarzinom kontraindiziert? DMW 45:1774Google Scholar
- Garmenia F, Kesserü E, Llerena LA (1973) Serum LH concentrations in women under contraceptive treatment with estrogen-free progestagens. Horm Metab Res 5:134CrossRefGoogle Scholar
- Gaspard UJ, Dubois M, Gillain D, Franchimont P, Duvivier J (1984) Ovarian function is effectively inhibited by a low-dose triphasic oral contraceptive containing ethinylestradiol and levonorgestrel. Contraception 29:305PubMedCrossRefGoogle Scholar
- Gerstman BB, Piper JM, Tomita DK, Ferguson WJ (1991) Oral contraceptive estrogen dose and the risk of deep venous thromboembolic disease. Am J Epidemiol 133:32PubMedGoogle Scholar
- Goebel R, Junkermann H, Fournier von D (1989) Danazolthe-rapie bei gutartigen Brusterkrankungen. Gynäkologe 22:262PubMedGoogle Scholar
- Goldstein JL, Brown MS (1977) The low-density lipoprotein pathway and its relation to atherosclerosis. Ann Rev Bio-chem 46: 897CrossRefGoogle Scholar
- Goldzieher JW, Kleber JW, Moses LE, Rathmacher RP (1970) A cross-sectional study of plasma FSH and LH levels in women using sequential, combination or injectable steroid contraceptives over long periods of time. Contraception 2: 225CrossRefGoogle Scholar
- Goldzieher JW, Moses LE, Averkin E, Scheel C, Taber BZ (1971 a) A placebo controlled double blind crossover investigation of the side effects attributed to oral contraceptives. Fertil Steril 22: 609PubMedGoogle Scholar
- Goldzieher JW, Moses LE, Averkin E, Scheel C, Taber BZ (1971b) Nervousness and depression attributed to oral contraceptives: A double-blind, placebo-controlled study. Am J Obstet Gynecol 111:1013PubMedGoogle Scholar
- Göttlicher S, Madjaric J (1981) Neue Ergebnisse zur Frage eines Zusammenhangs zwischen oraler Kontrazeption und vaginalem Sproßpilzbefall. Geburtshilfe Frauenheilkd 41: 630PubMedCrossRefGoogle Scholar
- Gray RH (1985) Reduced risk of pelvic inflammatory disease with injectable contraceptives. Lancet 1:1046PubMedCrossRefGoogle Scholar
- Guillebaud J (1983) The 150/30 formulation. Experience in the United Kingdom. J Reprod Med 28 (Suppl): 66PubMedGoogle Scholar
- Hammerstein J (1977) Komplikationen und Spätfolgen der Kontrazeption einschließlich der Sterilisation. Arch Gynäkol 224:1PubMedCrossRefGoogle Scholar
- Hammerstein J (1978) Mißbildungen nach Behandlung schwangerer Frauen mit weiblichen Sexualhormonen. Stellungnahme der „Ständigen Kommission Steroidtoxikologie” der Deutschen Gesellschaft für Endokrinologie, Ulm. Endo-krinologie-Information, Demeter, Gräfelfing 3:102Google Scholar
- Hammerstein J (1984) Grundsätzliche Betrachtung zur Wahl der Methode bei Mann und Frau. Gynäkologe 17:156PubMedGoogle Scholar
- Hammerstein J (1990) Risk/benefit of oral contraceptives. (Vortrag auf dem III. Internationalen Symposium zur Kontrazeption, Heidelberg, 19.–23.6.1990)Google Scholar
- Hanson M, Hatcher RA, Mishell DR, Notelovitz M, Spellacy WN (1985) Update on oral contraceptives. J Reprod Med 30 (Suppl): 691PubMedGoogle Scholar
- Harlap S, Shiono PH, Ramcharan S (1985) Congenital abnormalities in the offspring of women who used oral and other contraceptives around the time of conception. Int J Fertil 30:39PubMedGoogle Scholar
- Helmrich SP, Rosenberg L, Kaufman DW, Strom B, Shapiro S (1987) Venous thromboembolism in relation to oral contraceptive use. Obstet Gynecol 69: 91PubMedGoogle Scholar
- Hirvonen E, Stenman UH, Mälkönen M, Rasi V, Vartiainen E, Ylöstalo P (1988) New natural oestradiol/cyproterone acetate oral contraceptive for pre-menopausal women. Maturi-tas 10: 201CrossRefGoogle Scholar
- Hislop TG, Threlfall WJ (1984) Oral contraceptives and benign breast disease. Am J Epidemiol 120: 273PubMedGoogle Scholar
- Hocevar V, Rausch-Strooman JG (1968) Zur Frage der Behandlung der akuten intermittierenden Porphyrie mit Ovulationshemmern. Klin Wochenschr 46:1114PubMedCrossRefGoogle Scholar
- Hofmann AD (1984a) Contraception in adolescence: a review. 1. Psychosocial aspects. Bull WHO 62:151PubMedGoogle Scholar
- Hofmann AD (1984b) Contraception in adolescene: a review. 2. Biomedical aspects. Bull WHO 62:331PubMedGoogle Scholar
- Hollwich F, Verbeck B (1969) Nebenwirkungen der Ovulationshemmer am Auge. Dtsch Med Wochenschr 94:1761PubMedGoogle Scholar
- Hopmann R (1968) Akute intermittierende ovulozyklische Porphyrie und ihre Behandlung. Dtsch Med Wochenschr 93: 76PubMedCrossRefGoogle Scholar
- Huber FB (1967) Schwangerschaft und orale hormonelle Contraceptiva bei Porphyriekranken. Schweiz Med Wochenschr 97:1498PubMedGoogle Scholar
- Huggins GR, Zucker PK (1987) Oral contraceptives and neoplasia: 1987 update. Fertil Steril 47:733PubMedGoogle Scholar
- Hugo von R (1986) Die Bedeutung der Sexualsteroide für die Entstehung venöser Gefäßerkrankungen der Frau. Hormonale Kontrazeption und Kreislauf. 6. Internationales Gespräch Münster/München. Informed, Gräfelfing, S 59Google Scholar
- Ippen H, Tesche S (1972) Das „Chloasma” außerhalb der Gravidität. Hautarzt 23: 21PubMedGoogle Scholar
- Jain AK (1976) Cigarette smoking, use of oral contraceptives and myocardial infarction. Am J Obstet Gynecol 126:301PubMedGoogle Scholar
- Janerich DT, Glebatis DM, Dugan JM (1977) Benign breast disease and oral contraceptive use. JAMA 237: 2199PubMedCrossRefGoogle Scholar
- Jick H, Porter J, Rothman KJ (1978a) Oral contraceptives and nonfatal stroke in healthy young women. Ann Intern Med 88: 58CrossRefGoogle Scholar
- Jick H, Dinan B, Kenneth J, Rothman KJ (1978b) Oral contraceptives and nonfatal myocardial infarction. JAMA 239: 1403PubMedCrossRefGoogle Scholar
- Jick SS, Walker AM, Stergachis A, Jick H (1989) Oral contraceptives and breast cancer. Br J Cancer 59: 618PubMedCrossRefGoogle Scholar
- Jick H, Jick SS, Gurewich V, Myers MW, Vasilakis C (1995) Risk of idiopathic cardiovascular death and nonfatal venous thromboembolism in women using oral contraceptives with differing progestagen components. Lancet 346:1589PubMedCrossRefGoogle Scholar
- Judd SJ, Kerin J (1986) Contraception and diabetes mellitus. Clin Reprod Fertil 4: 297PubMedGoogle Scholar
- Kaiser R, Kloppenburg W, Ehmke H, Schwenk H (1987) Menstruationszyklus nach hormonaler Wachstumshemmung bei Mädchen. Geburtshilfe Frauenheilkd 47: 410PubMedCrossRefGoogle Scholar
- Kalkhoff RK (1972) Effects of oral contraceptive agents and sex steroids on carbohydrate metabolism. Ann Rev Med 23: 429PubMedCrossRefGoogle Scholar
- Kalkhoff RK (1982) Metabolic effects of progesterone. Am J Obstet Gynecol 142:735PubMedGoogle Scholar
- Kasan PN, Andrews J (1980) Oral contraception and congenital abnormalities. Br J Obstet Gynaecol 87:545PubMedCrossRefGoogle Scholar
- Kaufman DW, Shapiro S, Slone D et al. (1980) Decreased risk of endometrial cancer among oral contraceptive users. N Engl J Med 303:1045PubMedCrossRefGoogle Scholar
- Kay CR, Hannaford PC (1988) Breast cancer and the pill a- a further report from the Royal College of General Practitioners’ oral contraception study. Br J Cancer 58: 675PubMedCrossRefGoogle Scholar
- Keifer WS, Scott JC (1977) Liver neoplasms and the oral contraceptives. Am J Obstet Gynecol 128: 448PubMedGoogle Scholar
- Keller PJ (1986) Chemie und Pharmakologie der synthetischen Gestagene. Endokrinologisches Arbeitstreffen „Kontrazeptive Gestagene”. Thieme, Stuttgart, S 3Google Scholar
- Killick S, Eyong E, Elstein M (1987) Ovarian follicular development in oral contraceptive cycles. Fertil Steril 48: 409PubMedGoogle Scholar
- Klinger G, Eick S, Klinger G, Pfister W, Oettel M (1996) Der Ein-fluß hormonaler Kontrazeptiva auf die mikrobielle Flora des gingivalen Sulkus. (Eingereicht bei Contraception)Google Scholar
- Knopp RH (1986) Arteriosclerosis risk. The roles of oral contraceptives and postmenopausal estrogens. J Reprod Med 31 (Suppl): 913PubMedGoogle Scholar
- Kornman KS, Loesche WJ (1979) The subgingival microbial flora during pregnancy. J Periodontal Res 15:111CrossRefGoogle Scholar
- Krahulec I, Urbanova O, Simko S (1977) Prispevok K Studiu zmien hlasu pri homronalnej antikoncepcii. (A contribution to the study of voice changes in hormonal contraception.) Ceskoslovenska Otolaryngologic 26: 234Google Scholar
- Kreek MJ, Sleisenger MH, Jeffries GH (1967) Recurrent cholestatic jaundice of pregnancy with demonstrated estrogen sensitivity. Am J Med 43:795PubMedCrossRefGoogle Scholar
- Kristen K (1976) Veränderungen der Mundschleimhaut während der Schwangerschaft und kontrazeptiver Hormonbehandlung. Fortschr Med 94: 52PubMedGoogle Scholar
- Kuhl H (1987) Progestagene zur Empfängnisverhütung. WMW 18: 433Google Scholar
- La Vecchia C, Franceschi S, Decarli A (1984) Oral contraceptive use and the risk of epithelial ovarian cancer. Br J Cancer 50:31PubMedCrossRefGoogle Scholar
- Lähteenmäki P (1992) Health benefits of a levonorgestrel releasing IUD. 7th Europ Congr Gynaecol Obstet, HelsinkiGoogle Scholar
- Landthaler M, Braun-Falco O (1985) Maligne Melanome in der Schwangerschaft. Dtsch Med Wochenschr 35:1319CrossRefGoogle Scholar
- Lauritzen C (1987) Hormonale Kontrazeption. Adam Pharma-verlag, EssenGoogle Scholar
- Leys D, Destée A, Petit H, Warot P (1987) Chorea associated with oral contraception. J Neurol 235: 46PubMedCrossRefGoogle Scholar
- Linn S, Schoenbaum SC, Monson RR, Rosner B, Stubblefield PG, Ryan KJ (1983) Lack of association between contraceptive usage and congenital malformations in offspring. Am J Obstet Gynecol 147: 923PubMedGoogle Scholar
- Loudon NB, Foxwell M, Potts DM, Guild AL, Short RV (1977) Acceptability of an oral contraceptive that reduces the frequency of menstruation: the tri-cycle pill regiment. Br Med J II: 487CrossRefGoogle Scholar
- Louv WC, Austin H, Perlman J, Alexander WJ (1989) Oral contraceptive use and the risk of chlamydial and gonococcal infections. Am J Obstet Gynecol 160:396PubMedCrossRefGoogle Scholar
- Lundström V, Geijerstam G (1983) Treatment of primary dysmenorrhea. Acta Obstet Gynecol Scand 113 (Suppl): 83CrossRefGoogle Scholar
- Luukkainen T, Alionen H, Haukkamaa M, Lähteenmäki P, Nils-son CG, Toivonen J (1986) Five years experience with Levo-norgestrel-releasing IUDs. Contraception 33:139PubMedCrossRefGoogle Scholar
- Magos AL, Brincat M, Studd JWW et al. (1985) Amenorrhea and endometrial atrophy with continuous oral estrogen and progestogen therapy in postmenopausal women. Obstet Gynecol 65: 496PubMedGoogle Scholar
- Mall-Haefeli M, Werner-Zodrow I, Huber PR, Edelmann A (1988) Oral contraception and ovarian function. In: Runne-baum B, Rabe T, Kiesel L (eds) Female contraception, update and trends. Springer, Berlin Heidelberg New YorkGoogle Scholar
- Mammen EF (1982) Oral contraceptives and blood coagulation. A critical review. Am J Obstet Gynecol 142: 781PubMedGoogle Scholar
- Mammen EF (1986) Der Einfluß oraler Kontrazeptiva auf das hämostatische System. Hormonale Kontrazeption und Herzkreislauf. 6. Internationales Gespräch Münster/München 1986. Informed, Gräfelfing, S 47Google Scholar
- Mammen EF (1987) Wirkung oraler Kontrazeptiva auf die Blutgerinnung. In: Beller FK, Giesing M, Graeff H (Hrsg) Hormonale Kontrazeption und Herzkreislauf. Informed, Gräfe-ling, S 85Google Scholar
- Mammen EF (1990) Epidemiologische Studien zur Hämostase bei Benutzern oraler Kontrazeptiva. In: Keil TU (Hrsg) Kontrazeption — Nutzen — Probleme — Risiken — Perspektiven (III. Internationales Symposium über Kontrazeption, Heidelberg, 19.–23.6.1990). Urban & Vogel, München, S 48Google Scholar
- Mann RD (1990) Oral contraceptives and breast cancer. Parthenon, Casterton HallGoogle Scholar
- Mason B, Oakley N, Wynn V (1973) Studies of carbohydrate and lipid metabolism in women developing hypertension on oral contraceptives. Br Med J III: 317CrossRefGoogle Scholar
- Mathur AK, Gatter RA (1988) Chorea as the initial presentation of oral contraceptive induced systemic lupus erythematosus. J Rheumatol 15: 6Google Scholar
- McPherson K, Vessey MP, Neil A, Doll R, Jones L, Roberts M (1987) Early oral contraceptive use and breast cancer: results of another case-control study. Br J Cancer 56: 653PubMedCrossRefGoogle Scholar
- Meirik O, Farley TMM, Lund E et al. (1989) Breast cancer and oral contraceptives: patterns of risk among parous and nulli-parous women — further analysis of the Swedish-Norwegian material. Contraception 39:471PubMedCrossRefGoogle Scholar
- Meng M (1972) Erfahrungen mit der Minipille. Schweiz Rundsch Med (Praxis) 61: 519Google Scholar
- Miller DR, Rosenberg L, Kaufman DW, Stolley P, Warshauer ME, Shapiro S (1989) Breast cancer before age 45 and oral contraceptive use: new findings. Am J Epidemiol 129: 269PubMedGoogle Scholar
- Milsom I, Andersch B (1984) Effect of various oral contraceptive combinations on dysmenorrhea. Gynecol Obstet Invest 17: 284PubMedCrossRefGoogle Scholar
- Mishell DR (1982) Noncontraceptive health benefits of oral steroidal contraceptives. Am J Obstet Gynecol 142: 809PubMedGoogle Scholar
- Molina R, Thomas DB, Dabancens A, Lopez J, Ray RM, Martinez L, Salas O (1988) Oral contraceptives and cervical carcinoma in situ in Chile. Cancer Res 48:1011PubMedGoogle Scholar
- Molina R, Martinez C, Salas O et al. (1989) Combined oral contraceptives and liver cancer. Int J Cancer 43: 254CrossRefGoogle Scholar
- Morrow P, Nakamura R, Schlaerth J, Gaddis O, Eddy G (1985) The influence of oral contraceptives on the postmolar human chorionic gonadotropin regression curve. Am J Obstet Gynecol 151: 906PubMedGoogle Scholar
- Newton J (1988) Contraception for the women aged 35 year and over. Maturitas 1: 89PubMedCrossRefGoogle Scholar
- Nocke W (1978) Sind weibliche Sexualsteroide teratogen? Rückblick — Zwischenbilanz — Konsequenzen. Gynäkologe 11:119Google Scholar
- Olsson H, Lindahl B, Ranstam J, Borg A, Fernö M, Norgren A (1987) Permanent alterations induced in plasma prolactin and estrogen receptor concentration in benign and malignant tissue of women who started oral contraceptive use at an early age. Anticancer Res 7: 853PubMedGoogle Scholar
- Olsson H, Möller TR, Ranstam J, Borg A, Fernö M (1988) Early oral contraceptive use as a prognostic factor in breast cancer. Anticancer Res 8: 29PubMedGoogle Scholar
- Olsson H, Möller TR, Ranstam J (1989) Early oral contraceptive use and breast cancer among premenopausal women. Final report from a study in southern Sweden. J Natl Cancer Inst 81:1000PubMedCrossRefGoogle Scholar
- Pahn J, Göretzlehner G (1978) Stimmstörungen durch hormonale Kontrazeptiva. Zentralbl Gynäkol 100: 341PubMedGoogle Scholar
- Pahn J, Göretzlehner G (1979) Hormonale Kontrazeptiva und Stimmstörungen. HNO-Praxis 4: 220Google Scholar
- Pain JA, Gimson AES, Williams R, Howard ER (1991) Focal nodular hyperplasia of the liver: results of treatment and options of management. GUT 32:524PubMedCrossRefGoogle Scholar
- Pascher W, Bauer H (1984) Entwicklungsstörungen der Stimme. In: Pascher W, Bauer H (Hrsg) Differentialdiagnose von Sprach-, Stimm- und Hörstörungen. Thieme, StuttgartGoogle Scholar
- Pearl R (1932) Contraception and fertility in 2000 women. Hum Biol 4: 363Google Scholar
- Perlroth MG, Marver HS, Tschudy DP (1965) Oral contraceptive agents and the management of acute intermittent porphyria. JAMA 194:1037PubMedCrossRefGoogle Scholar
- Petersen P (1978) Seelische Veränderungen bei hormonaler Kontrazeption der Frau. Dtsch ärztebl 18:1075Google Scholar
- Petitti DB (1986) Epidemiologic assessment of the risks of oral contraception. J Reprod Med 31: 887PubMedGoogle Scholar
- Petitti DB, Wingerd J (1978) Use of oral contraceptives, cigarette smoking, and risk of subarachnoid haemorrhage. Lancet II: 234CrossRefGoogle Scholar
- Petitti DB, Wingerd J, Pellegrin F, Ramcharan S (1978) Oral contraceptives, smoking, and other factors in relation to risk of venous thromboembolic disease. Am J Epidemiol 108: 480PubMedGoogle Scholar
- Petitti DB, Wingerd J, Pellegrin F, Ramcharan S (1979) Risk of vascular disease in women. JAMA 242:1150PubMedCrossRefGoogle Scholar
- Pike MC, Henderson BE, Casagrande JT, Rosario I, Gray GE (1981) Oral contraceptive use and early abortion as risk factors for breast in young women. Br J Cancer 43: 72PubMedCrossRefGoogle Scholar
- Pituitary Adenoma Study Group (1983) Pituitary adenomas and oral contraceptives: a multicenter case control study. Fertil Steril 39: 753Google Scholar
- Podoshin L, Gertner R, Fradis M, Feiglin H, Eibschitz I, Sharf M, Reiter A (1978) Oral contraceptives pills and clinical otosclerosis. Int J Gynaecol Obstet 15: 554PubMedGoogle Scholar
- Poettgen H (1989) Wenn ich Jugendlichen die Pille verordnen soll. Sexualmedizin 6:310Google Scholar
- Porter JB, Hunter JR, Jick H, Stergachis A (1985) Oral contraceptives and nonfatal vascular disease. Obstet Gynecol 66:1PubMedGoogle Scholar
- Porter JB, Jick H, Walker AM (1987) Mortality among oral contraceptive users. Obstet Gynecol 70: 29PubMedGoogle Scholar
- Poser S, Raun NE, Wikström J, Poser W (1979) Pregnancy, oral contraceptives and multiple sclerosis. Acta Neurol Scand 59: 108PubMedCrossRefGoogle Scholar
- Rabe T, Runnebaum B (1982) Kontrazeption. Springer, Berlin Heidelberg New York TokyoCrossRefGoogle Scholar
- Rabe T, Grunwald K, Runnebaum B (1988) Pille und Kohlenhydratstoffwechsel. Fertilität 4: 97Google Scholar
- Rahn KH (1984) äußerungen von Schäden an der Haut. In: Rahn KH (Hrsg) Erkrankungen durch Arzneimittel. Thieme, StuttgartGoogle Scholar
- Ramcharan S (1974) The Walnut Creek contraceptive drug study: a prospective study of the side effects of oral contraceptives, vol I. Findings in oral contraceptive users and nonusers at entry into the study. US Government Printing Office, Washington DCGoogle Scholar
- Ramcharan S (1976) The Walnut Creek contraceptive drug study: a prospective study of the side effects of oral contraceptives, vol II. Additional findings of oral contraceptive users and nonusers. US Government Printing Office, Washington DCGoogle Scholar
- Ramcharan S, Pellegrin FA, Ray R, Hsu JP (1980) The Walnut Creek contraceptive drug study, vol III. Center for Population Research, Bethesda MDGoogle Scholar
- Realini JP, Goldzieher JW (1985) Oral contraceptives and cardiovascular disease: a critique of the epidemiologic studies. Am J Obstet Gynecol 152: 729PubMedGoogle Scholar
- Rechenberger I (1989) Psychosomatische Aspekte des prämenstruellen Syndroms. Gynäkologe 22:332PubMedGoogle Scholar
- Reisert PM (1983) Hormonell verursachte Stimmstörungen. Therapiewoche 33:3661Google Scholar
- Resnik S (1967) Melasma induced by oral contraceptive drugs. JAMA 199: 601PubMedCrossRefGoogle Scholar
- Rice-Wray E, Beristain II, Cervantes A (1972) Clinical study of a continuous daily microdose progestogen contraceptive -d-norgestrel. Contraception 5: 279PubMedCrossRefGoogle Scholar
- Rocheis R, Nover A (1980) Nebenwirkungen oraler Kontrazeptiva am Auge. Geburtshilfe Frauenheilkd 40: 713CrossRefGoogle Scholar
- Rock CL, Hall WD (1978) Effect of oral contraceptives on salt taste thresholds. Clin Res 26:368AGoogle Scholar
- Rooks JB, Ory HW, Ishak K, Strauss LT, Greenspan JR, Paganini-Hill A, Tyler CW (1979) Epidemiology of hepatocellular adenoma. The role of oral contraceptive use. JAMA 242: 644PubMedCrossRefGoogle Scholar
- Rosenberg L, Shapiro S, Stone D, Kaufman DW et al. (1982) Epithelial ovarian cancer and combination oral contraceptives. JAMA 247:3210PubMedCrossRefGoogle Scholar
- Royal College of General Practitioners (1974) Oral contraceptives and health; an interim report from the oral contraception study of the Royal College of General Practitioners. Pitman, New YorkGoogle Scholar
- Royal College of General Practitioners’ Oral Contraceptive Study (1976a) The outcome of pregnancy in former contraceptive users. Br J Obstet Gynaecol 83: 608CrossRefGoogle Scholar
- Royal College of General Practitioners’ Oral Contraceptive Study (1976b) Pregnancy after oral contraception. Lancet II: 555Google Scholar
- Royal College of General Practitioners’ Oral Contraceptive Study (1977a) Effect of hypertension and benign breast disease of progestagen component in combined oral contraceptives. Lancet I: 624Google Scholar
- Royal College of General Practitioners’ Oral Contraceptive Study (1977b) Mortality among oral contraceptive users. Lancet II: 727Google Scholar
- Royal College of General Practitioners’ Oral Contraceptive Study (1978a) Oral contraceptives, venous thrombosis, and varicose veins. J R Coll Gen Pract 28:393Google Scholar
- Royal College of General Practitioners’ Oral Contraceptive Study (1978b) Reduction in incidence of rheumatoid arthritis associated with oral contraceptives. Lancet I: 569Google Scholar
- Royal College of General Practitioners’ Oral Contraceptive Study (1981a) Further analysis of mortality in oral contraceptive users. Lancet I: 541Google Scholar
- Royal College of General Practitioners’ Oral Contraceptive Study (1981b) Breast cancer and oral contraceptives: findings in Royal College of General Practitioners’ study. Br Med J 282: 2089CrossRefGoogle Scholar
- Royal College of General Practitioners (1983) Incidence of arterial disease among oral contraceptive users. J R Coll Gen Pract 33:75Google Scholar
- Rubin GL, Ory HW, Layde PM (1982) Oral contraceptives and pelvic inflammatory disease. Am J Obstet Gynecol 144: 630PubMedGoogle Scholar
- Runnebaum B, Rabe T (1987) New progestogens in oral contraceptives. Am J Obstet Gynecol 157:1059PubMedGoogle Scholar
- Rydén G, Fahraeus L, Molin L, Ahman K (1979) Do contraceptives influence the incidence of acute pelvic inflammatory diseases in women with gonorrhea? Contraception 20: 149PubMedCrossRefGoogle Scholar
- Samani F, Bolzonello P, Fior R, Elia A (1987) Effects on hearing during prolonged oral contraceptive use. Contraception 35:41PubMedCrossRefGoogle Scholar
- Savolainen E, Saksela E, Saxen L (1981) Teratogenic hazards of oral contraceptives analyzed in a national malformation register. Am J Obstet Gynecol 140: 521PubMedGoogle Scholar
- Schindler AE (1984) Hormonale postkoitale Kontrazeption. Frauenarzt 2: 47Google Scholar
- Schindler AE (1989) ätiologie und Epidemiologie gutartiger Brustveränderungen der Brust. Gynäkologe 22: 212PubMedGoogle Scholar
- Schlesselman JJ, Stadel BV, Murray P, Wingo PA, Rubin GL (1987) Consistency and plausibility in epidemiologic analysis: application to breast cancer in relation to use of oral contraceptives. J Chron Dis 40:1033PubMedCrossRefGoogle Scholar
- Schley G, Anlauf M, Bock KD (1976) Orale Kontrazeptiva zur Prophylaxe akuter Schübe der intermittierenden Porphyrie. Dtsch Med Wochenschr 101:1901PubMedCrossRefGoogle Scholar
- Scholten PC, van Eykeren MA, Christiaens GCML, Haspels AA (1989) Menstrual blood loss with Levonorgestrel Nova-T and multiload CU 250 intrauterine devices. In: Scholten PC. The Levonorgestrel IUD — clinical performance and impact on menstruation. Habil Schrift Dept Obstet Gynaecol, University Hospital Uetrecht p. 35Google Scholar
- Schützel H, Neumann F (1988) Potential risk of intrauterine feminization in man from the antiandrogen cyproterone acetate (CPA) in recommended dose regiments. (XII World Congress of Gynecology and Obstetrics, Rio de Janeiro, Oct 23–28 1988, under auspices of International Federation of Gynecology & Obstetrics) Abstracts, p 703Google Scholar
- Schwartz U (1986) Kontrazeption in der Prämenopause. Gynäkologe 19: 254PubMedGoogle Scholar
- Scott LD, Katz AR, Duke JH, Cowan DF, Maklad NF (1984) Oral contraceptives, pregnancy, and focal nodular hyperplasia of the liver. JAMA 251:1461PubMedCrossRefGoogle Scholar
- Seed M, Godsland IF, Wynn V, Jacobs HS (1984) The effects of cyproterone acetate and ethinyl o estradiol on carbohydrate metabolism. Clin Endocrinol 21: 689CrossRefGoogle Scholar
- Shaffer EA, Taylor PJ, Logan K et al. (1984) The effect of a progestin on gallbladder function in young women. Am J Obstet Gynecol 148: 504PubMedGoogle Scholar
- Shaw RW (1987) Adverse longterm effects of oral contraceptives: a review. Br J Obstet Gynecol 94: 724CrossRefGoogle Scholar
- Sillem M, Teichmann AT (1994) The liver. In: Goldzieher J (ed) Pharmacology of the contraceptive steroids. Raven Press, New YorkGoogle Scholar
- Silverberg SG, Makowski EL (1975) Endometrial carcinoma in young women taking oral contraceptive agents. Obstet Gynecol 46:503PubMedGoogle Scholar
- Silverberg SG, Haukkamaa M, Arko H, Nilsson CG, Luukkainen T (1986) Endometrial morphology during long-term use of Levonorgestrel-releasing intrauterine devices. Int J Gynaecol Pathol 5: 235CrossRefGoogle Scholar
- Skouby SO (1988) Oral contraceptives: effects on glucose and lipid metabolism in insulin-dependent diabetic women and women with previous gestational diabetes. Danish Med Bull 35: 157PubMedGoogle Scholar
- Skouby SO, Jensen BM, Kühl C, Molsted-Pedersen L, Svenstrup B, Nielsen J (1985) Hormonal contraception in diabetic women: acceptability and influence on diabetes control and ovarian function of a non-alkylated estrogen/progestogen compound. Contraception 32: 23PubMedCrossRefGoogle Scholar
- Skouby SO, Molsted-Pedersen L, Kühl C, Bennet P (1986) Oral contraceptives in diabetic women: metabolic effects of four compounds with different estrogen/progestogen profiles. Fertil Steril 46: 858PubMedGoogle Scholar
- Sooriyamoorthy M, Gower DB (1989) Hormonal influences on gingival tissue: relationship to periodontal disease. J Clin Periodontol 16: 201PubMedCrossRefGoogle Scholar
- Spellacy WN (1982) Carbohydrate metabolism during treatment with estrogen, progestogen, and low dose oral contraceptives. Am J Obstet Gynecol 142: 732PubMedGoogle Scholar
- Spellacy WN, Carlson KL, Birk SA (1967) Carbohydrate metabolic studies after six cycles of combined type oral contraceptive tablets. Diabetes 16: 590PubMedGoogle Scholar
- Spellacy WN, Carlson KL, Schade SL (1968) Effect of a sequential oral contraceptive on plasma insulin and blood glucose levels after 6 months’treatment. Am J Obstet Gynecol 101:672Google Scholar
- Stadel BV, Lai S, Schlesselman JJ, Murray P (1988) Oral contraceptives and premenopausal breast cancer in nulliparous women. Contraception 38: 287PubMedCrossRefGoogle Scholar
- Stamm H, Kraus J (1977) Pharmakotherapeutische Grundlagen der hormonellen Kontrazeption. Mod Arzneimittel Ther 1/4: 243Google Scholar
- Stampfer MJ, Wille« WC, Colditz GA et al. (1988) A prospective study of past use of oral contraceptive agents and risk of cardiovascular diseases. N Engl J Med 319:1313PubMedCrossRefGoogle Scholar
- Stephan F, Réville P (1977) Diabetes und östrogene-Gestagene. MMW 119: 663Google Scholar
- Stern E, Forsythe AB, Yonkels L, Coeffelt CC (1977) Steroid contraceptive use and cervical dysplasia: increased risk in progression. Science 196:1460PubMedCrossRefGoogle Scholar
- Stone M, Bagshawe KD (1979) An analysis of the influence of maternal age, gestational age, contraceptive method, and the mode of primary treatment of patients with hydatidiform moles on the incidence of subsequent chemotherapy. Br J Obstet Gynecol 86: 782CrossRefGoogle Scholar
- Svensson L, Weström L, Mardh PA (1984) Contraceptives and acute salpingitis. JAMA 251: 2553PubMedCrossRefGoogle Scholar
- Sweet JB, Butler DP (1977) Increased incidence of postoperative localized osteitis in mandibular third molar surgery associated with patients using oral contraceptives. Am J Obstet Gynecol 127:518PubMedGoogle Scholar
- Tankeyoon M, Dusitsin N, Chalapati S (1984) Effects of hormonal contraceptives on milk volume and infant growth. Contraception 30:505PubMedCrossRefGoogle Scholar
- Taubert HD, Kuhl H (1995) Kontrazeption mit Hormonen. Thieme, Stuttgart, S 172Google Scholar
- Tayob Y, Adams J, Jacobs HS, Guillebaud J (1985) Ultrasound demonstration of increased frequency of functional ovarian cysts in women using progestogen only oral contraception. Br J Obstet Gynecol 92:1003CrossRefGoogle Scholar
- Teichmann AT (1996) Empfängnisverhütung. Thieme, StuttgartGoogle Scholar
- Teichmann AT, Wieland H, Brockerhoff P (1989) Sexualhormone, Arteriosklerose und Fettstoffwechsel der Frau. Wissenschaftliche Verlagsgesellschaft, StuttgartGoogle Scholar
- Terblanche J (1978) Liver tumours associated with the use of contraceptive pills. S Afr MedJ 53: 439Google Scholar
- Tietze C, Lewit S (1978) Life risks associated with reversible methods of fertility regulation. (International symposium on a reappraisal of fertility control: benefits vs risks, Montreal)Google Scholar
- Tremblay RR, Dube JY (1974) Plasma concentration of free and non-TeBG bound testosterone in women on oral contraceptives. Contraception 10: 599PubMedCrossRefGoogle Scholar
- Ursin G, Peter RK, Henderson BE, Ablaing G III, Monroe KR, Pike MC (1994) Oral contraceptive use and adenocarcinoma of cervix. Lancet 344:1390PubMedCrossRefGoogle Scholar
- Vail JT (1967) Porphyria cutanea tarda and estrogens. JAMA 201:101CrossRefGoogle Scholar
- Vandenbroucke JP, Koster T, Briet E, Reitsma PH, Bertina RM, Rosendaal FR (1994) Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation. Lancet 344:1453PubMedCrossRefGoogle Scholar
- Vesper B, Feustel S (1988) Die Beeinflussung der Serumlipide und der Glucosetoleranz durch Sequenz-Ovosiston und Minisiston. Zentralbl Gynäkol 110: 241PubMedGoogle Scholar
- Vessey MP, Doll R, Sutton PM (1972) Oral contraceptives and breast neoplasia: a retrospective study. Br Med J III: 719CrossRefGoogle Scholar
- Vessey MP, Doll R, Sutton PM (1975) Oral contraceptives and breast cancer: progress report of an epidemiological study. Lancet I: 941CrossRefGoogle Scholar
- Vessey MP, Doll R, Peto R, Johnson B, Wiggins P (1976) A long-term follow-up study of women using different methods of contraception — an interim report. J Biosoc Sci 8:375CrossRefGoogle Scholar
- Vessey MP, McPherson K, Johnson B (1977) Mortality among women participating in the Oxford/Family Planning Association Contraceptive Study. Lancet II: 731CrossRefGoogle Scholar
- Vessey MP, Wright NH, McPherson K, Yeates P (1978) Fertility after stopping different methods of contraception. Br Med J 1: 265PubMedCrossRefGoogle Scholar
- Vessey MP, Doll R, Jones K, McPherson K, Yeates P (1979) An epidemiological study of oral contraceptives and breast cancer. Br Med J 1:1757PubMedCrossRefGoogle Scholar
- Vessey MP, McPherson K, Yeates D, Doll R (1982) Oral contraceptive use and abortion before first term pregnancy in relation to breast cancer risk. Br J Cancer 45:327PubMedCrossRefGoogle Scholar
- Vessey MP, Metcalfe A, Wells C, McPherson K, Westhoff C, Yeates D (1987) Ovarian neoplasms, functional ovarian cysts, and oral contraceptives. Br Med J 294:1518CrossRefGoogle Scholar
- Vessey MP, McPherson K, Villard-Mackintosh L, Yeates D (1989) Oral contraceptives and breast cancer: latest findings in a large cohort study. Br J Cancer 59: 613PubMedCrossRefGoogle Scholar
- Washington AE, Gove S, Schachter J et al. (1985) Oral contraceptives, chlamydia trachomatis infection, and pelvic inflammatory disease. JAMA 253: 2246PubMedCrossRefGoogle Scholar
- Weir RJ, Davies DL, Fraser R, Morton JJ, Tree M, Wilson A (1975) Contraceptive steroids and hypertension. J Steroid Biochem 6: 961PubMedCrossRefGoogle Scholar
- Weir JC, Silberman SL, Cohen LA (1979) Recurring oral pregnancy tumors. Obstet Gynecol 54: 358PubMedGoogle Scholar
- Weisberg E (1982) Fertility after discontinuation of oral contraceptives. Clin Reprod Fertil 1: 261PubMedGoogle Scholar
- Weiland FH, Hellman ES, Collins A, Hunter GW, Tschudy DP (1964) Factors affecting the excretion of porphyrin precursors by patients with acute intermittent porphyria. II. The effect of ethinyl estradiol. Metabolism 13: 251CrossRefGoogle Scholar
- Wenderlein JM (1981) Keine Häufung von Depressionen unter hormonaler Kontrazeption. Med Klin 76: 288PubMedGoogle Scholar
- WHO (1995a) Effect of different progestagens in low oestrogen oral contraceptives on venous thromboembolic disease. Lancet 346:1582Google Scholar
- WHO (1995b) Venous thromboembolic disease and combined oral contraceptives: results of international multicentre case control study. Lancet 346:1575Google Scholar
- Wiebe RH, Morris CV (1984) Effect of an oral contraceptive on adrenal and ovarian androgenic steroids. Obstet Gynecol 63: 12PubMedGoogle Scholar
- Wingrave SJ, Kay CR, Vessey MP (1979) Oral contraceptives and diabetes mellitus. Br Med J 1: 23PubMedCrossRefGoogle Scholar
- Winkler UH, Schindler AE, Endrikat J, Düsterberg B (1996) A comparative study of the effects of the hemostatic system of two monophasic gestodene oral contraceptives containing 20 ug and 30 ug ethinylestradiol. Contraception 53: 75PubMedCrossRefGoogle Scholar
- Wiseman RA (1984) Absence of correlation between oral contraceptive usage and cardiovascular mortality. Int J Fertil 29: 198PubMedGoogle Scholar
- Wissenschaftlicher Beirat der Bundesärztekammer (1984) Hinweise zur Verordnung oraler Kontrazeptiva. Dtsch ärztebl 81: 1Google Scholar
- Woods JW (1988) Oral contraceptives and hypertension. Hypertension 11 (Suppl II): 11Google Scholar
- Woutersz TB (1983) A new ultra-low-dose combination oral contraceptive. J Reprod Med 28 (Suppl): 81PubMedGoogle Scholar
- Wu ML, Whittemore AS, Paffenbarger RS Jr et al. (1988) Personal and environmental characteristics related to epithelial ovarian cancer. I. Reproductive and menstrual events and oral contraceptive use. Am J Epidemiol 128:1216PubMedGoogle Scholar
- Wynn V (1982a) Effect of duration of lowdose oral contraceptive administration on carbohydrate metabolism. Am J Obstet Gynecol 142: 739PubMedGoogle Scholar
- Wynn V (1982b) Cardiovascular effects of progestins in oral contraceptives. Am J Obstet Gynecol 142: 718PubMedGoogle Scholar
- Wynn V, Godsland I (1986) Effects of oral contraceptives on carbohydrate metabolism. J Reprod Med 31: 892PubMedGoogle Scholar
- Yuen BH, Burch P (1983) Relationship of oral contraceptives and the intrauterine contraceptive devices to the regression of concentration of the beta subunit of human chorionic gonadotropin and invasive complications after molar pregnancy. Am J Obstet Gynecol 145: 214Google Scholar
- Yuzpe AA, Smith RP, Rademaker AW (1982) A multicenter clinical investigation employing ethinyl estradiol combined with dl-norgestrel as a postcoital contraceptive agent. Fertil Steril 37: 508PubMedGoogle Scholar
- Zaun H (1980) Orale Kontrazeptiva und Hautveränderungen. Dtsch ärztebl 77:2347Google Scholar
- Zaun H (1982) Dermatotrope Wirkungen hormonaler Kontrazeptiva. In: Kaiser R (Hrsg) Hormonale Kontrazeption -aktuelle medizinische und juristische Aspekte. Schering, Berlin, S 15Google Scholar
- Zimmermann T (1996) persönliche Mitteilung, Daten aus Erhebung der PharmaindustrieGoogle Scholar