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Magnetic Resonance of Myelin, Myelination, and Myelin Disorders pp 58–64Cite as

Metachromatic Leukodystrophy

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Abstract

Metachromatic leukodystrophy (MLD) is an autosomal recessive progressive demyelinating disorder. Its incidence is estimated to be between 1:40 000 and 1:130 000. The disease can be divided into three different subtypes: the late infantile, the juvenile and the adult variant. This subdivision is based on the age of onset, the duration, and the clinical picture of the disease. Within one family only one variant of MLD occurs.

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Authors and Affiliations

  1. Department of Child Neurology, Free University Hospital, De Boelelaan 1117, 1007 MB, Amsterdam, The Netherlands

    Marjo S. van der Knaap MD, PhD

  2. Department of Diagnostic Radiology, Free University Hospital, De Boelelaan 1117, 1007 MB, Amsterdam, The Netherlands

    Jacob Valk MD, PhD

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  1. Marjo S. van der Knaap MD, PhD
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  2. Jacob Valk MD, PhD
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© 1995 Springer-Verlag Berlin Heidelberg

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van der Knaap, M.S., Valk, J. (1995). Metachromatic Leukodystrophy. In: Magnetic Resonance of Myelin, Myelination, and Myelin Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03078-3_6

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  • DOI: https://doi.org/10.1007/978-3-662-03078-3_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-03080-6

  • Online ISBN: 978-3-662-03078-3

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