Inulin Absorption by Necturus Proximal Tubule and some Consequences thereof
Conference paper
Abstract
We have been engaged for many years in a systematic study of the mechanism of ion and water transport by the proximal tubule of Necturus kidney [6,7,12,15,17,18,19]. All of our results have been based on the premise that inulin was an acceptable reference substance for the measurement of water movement, being neither absorbed nor secreted by the epithelial cells in the tubule. Recently we have obtained compelling evidence that this premise does not obtain because inulin is absorbed by the proximal tubule of Necturus. It is the purpose of the present communication to recount this evidence and to reexamine our older conclusions in the light of this finding.
Preview
Unable to display preview. Download preview PDF.
References
- [1]Bott, P. A.: Amer. J. Physiol. 168, 107 (1952).Google Scholar
- [2]Cullis, W. C.: J. Physiol. (Lond.) 34, 250 (1906).Google Scholar
- [3]Gertz, K. H.: Pfliigers Arch. ges. Physiol. 276, 336 (1963).Google Scholar
- [4]Giebisch, G., R. M. Klose, G. Malnic, W. J. Sullivan, and E. E. Windhager: J. gen. Physiol. 47, 1175 (1964).CrossRefGoogle Scholar
- [5]Maunsbach, A.: J. Cell Biol. 19, 48A (1963).Google Scholar
- [6]Oken, D. E., and A. K. Solomon: Amer. J. Physiol. 204, 377 (1963).Google Scholar
- [7]Oken, D. E. G. Whittembury, E. E. Windhager, and A. K. Solomon: Amer. J. Physiol. 204, 372 (1963).Google Scholar
- [8]Page, E., and A. K. Solomon: J. gen. Physiol. 44, 327 (1960).CrossRefGoogle Scholar
- [9]Pidot, A. L., and J. M. Diamond: Nature (Lond.) 201, 701 (1964).CrossRefGoogle Scholar
- [10]Prosser, C. L., and S. J. F. Weinstein: Physiol. Zool. 23, 113 (1950).Google Scholar
- [11]Richards, A. N., P. A. Bott, and B. B. Westfall: Amer. J. Physiol. 123, 281 (1938).Google Scholar
- [12]Schatzmann, H. J., E. E. Windhager, and A. K. Solomon: Amer. J. Physiol. 195, 570 (1958).Google Scholar
- [13]Scott, W. N., D. L. Maude, I. H. Shehadeh, and A. K. Solomon: Physiologist 7, 249 (1964).Google Scholar
- [14]Shehadeh, I. H., D. L. Maude, W. N. Scott, and A. K. Solomon: Physiologist 7, 254 (1964).Google Scholar
- [15]Shipp, J. C., I. B. Hanenson, E. E. Windhager, H. J. Schatzmann, G. Whittembury, H. Yoshimura, and A. K. Solomon: Amer. J. Physiol. 195, 563 (1958).Google Scholar
- [16]Smith, H. W.: The Kidney. Chapter 3, pp. 47–52, Chapter 9. New York: Oxford University Press 1951.Google Scholar
- [17]Solomon, A. K.: Amer. J. Physiol. 204, 381 (1963).Google Scholar
- [18]Whittembury, G., D. E. Oken, E. E. Windhager, and A. K. Solomon: Amer. J. Physiol. 197, 1121 (1959).Google Scholar
- [19]Windhager, E. E., G. Whittembury, D. E. Oken, H. J. Schatzmann, and A. K. Solomon: Amer. J. Physiol. 197, 313 (1959).Google Scholar
Copyright information
© Springer-Verlag · Berlin · Heidelberg 1965