The Two Different Means of Achieving Dosage Compensation for X-linked Genes Employed by Drosophila and Mammals

  • Susumu Ohno
Part of the Monographs on Endocrinology book series (ENDOCRINOLOGY, volume 1)


As shown in the previous chapter, the X-linked genes of Drosophila are included in the euchromatic region which never becomes heterochromatic. The male is endowed with one dose, while the female receives two doses of the euchromatic region of the X. During the course of evolution of this insect, the dosage compensation mechanism must have developed one by one for each individual X-linked gene.


Placental Mammal Dosage Compensation Japanese Quail Euchromatic Region Dosage Compensation Mechanism 
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© Springer-Verlag Berlin · Heidelberg 1966

Authors and Affiliations

  • Susumu Ohno
    • 1
  1. 1.Department of BiologyCity of Hope MedicalDuarteUSA

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