Elucidation of So-called Sex-determining Factors

  • Susumu Ohno
Part of the Monographs on Endocrinology book series (ENDOCRINOLOGY, volume 1)


The chromosomal sex-determining mechanism quite obviously depends upon the presence of female-determining factors on one member and of male-determining factors on the other member of the sex chromosome pair. Yet, the exact nature of so-called sex-determining factors remains a riddle. While sex-linked genes are Mendelian genes which behave in a predictable manner, the sex-determining factors are elusive entities which have not permitted close scrutiny.


Gonadal Dysgenesis Functioning Female Somatic Cell Type Mendelian Gene Component Polypeptide 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1966

Authors and Affiliations

  • Susumu Ohno
    • 1
  1. 1.Department of BiologyCity of Hope MedicalDuarteUSA

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