Studies on the Viral Etiology of the Renal Adenocarcinoma of Rana pipiens (Lucké Tumor)

  • Allan Granoff
  • Maneth Gravell
  • R. W. Darlington
Chapter
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 1969)

Abstract

The presence of intranuclear acidophilic inclusion bodies and an increased incidence of tumors in frogs receiving cell-free tumor extracts led Lucke (1, 2) to postulate a viral etiology of the renal adenocarcinoma of Rana pipiens (Lucké tumor). Although this conclusion was reached over thirty years ago, propagation of a virus from R. pipiens capable of inducing renal tumors has not been achieved.

Keywords

Renal Carcinoma Fathead Minnow Intranuclear Inclusion Viral Etiology Leopard Frog 
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Copyright information

© Springer-Verlag New York Inc. 1969

Authors and Affiliations

  • Allan Granoff
    • 1
    • 2
  • Maneth Gravell
    • 1
    • 2
  • R. W. Darlington
    • 1
    • 2
  1. 1.Laboratory of VirologySt. Jude Children’s Research HospitalMemphisUSA
  2. 2.University of Tennessee Medical UnitsMemphisUSA

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