The Hypertrophied Heart pp 55-60 | Cite as
The reversal of the calcium pump of cardiac sarcoplasmic reticulum
Conference paper
Summary
The reversal of the calcium pump of cardiac sarcoplasmic reticulum (SR) prepared from dogs was investigated. Phosphorylation of the calcium transport ATPase by orthophosphate and ATP synthesis from ADP and orthophosphate by SR passively preloaded with calcium are demonstrated. The ADP-dependent calcium efflux from SR loaded with calcium in the presence of acetylphosphate is stoichiometrically coupled to ATP synthesis from ADP and orthophosphate.
Die Umkehr der Calcium-Pumpe des myokardialen sarkoplasmatischen Retikulums
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References
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© Dr. Dietrich Steinkopff Verlag, Darmstadt 1977