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Multimodale Therapieansätze bei der chirurgischen Therapie des Bronchialkarzinoms im Stadium III

  • Conference paper
Qualitätssicherung durch Zusammenarbeit in der Chirurgie

Part of the book series: Langenbecks Archiv für Chirurgie ((KONGRESSBAND,volume 1995))

  • 36 Accesses

Summary

In nonpretreated patients with tumor stage ‘limited disease,’ a combination of chemotherapy and radiotherapy leads to remission rates of 70%–95%. The mean survival time of patients is 12 months, in complete remissions 15–20 months. However, after 2 years, only 5%–10% of patients are free of relapse. In stage IV (metastatic disease) of non-small-cell lung cancer (NSCLC), chemotherapy is only palliative, with remission rates between 25%–45%. In stage III,new results with remission rates between 50%–70% suggest treatment with preoperative induction chemotherapy or new attempts with adjuvant chemotherapy, respectively.

Zusammenfassung

Im Stadium limited disease werden bei nicht-vorbehandelten Patienten durch die Kombination von Chemotherapie und Radiotherapie objektiv meßbare Remissionen in einer Häufigkeit von 70-95% erzielt. Die medianen Überlebensdauern der Patienten betragen 12 Monate, bei kompletten Remissionen 15-20 Monate. Nach 2 Jahren leben jedoch nur noch 5-10% der Patienten rezidivfrei. Bei den nicht-kleinz. Bronchialkarzinomen hat die Chemotherapie im Stadium IV mit Remissionsraten zwischen 25-45% ausschließlich palliativen Charakter. Neue Ergebnisse im Stadium III mit Remissionsraten zwischen 50-70% ergeben Ansätze für eine präoperative Induktionschemoth. bzw. einen erneuten Versuch der adjuvanten Chemotherapie.

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Author information

Authors and Affiliations

  1. Abteilung Innere Medizin-Onkologie, Thoraxklinik, Amalienstraße 5, 69120, Heidelberg, Deutschland

    P. Drings

  2. Lungenklinik Heckeshorn, Zum Heckeshorn 33, 14109, Berlin, Deutschland

    A. Fritzsche, R. Loddenkemper & D. Kaiser

  3. Marburg, Deutschland

    M. Wolf & K. Havemann

  4. Thoraxchirurgische Abteilung, Thoraxklinik, Amalienstraße 5, 69126, Heidelberg, Deutschland

    J. Schirren, W. Richter, C. Trainer, S. Trainer, P. Schneider, H. Bülzebruck & I. Vogt-Moykopf

  5. Thoraxchirurgische Abteilung, Klinik Schillerhöhe, Solitudestraße 18, 70839, Gerlingen, Deutschland

    G. Friedel, A. Linder, S. Weigang, P. Froeschle & H. Toomes

  6. Ruhrlandklinik, Tüschener Weg 40, 45239, Essen, Deutschland

    B. Kardjiev, W. Eberhardt, M. Stuschke & D. Greschuchna

  7. Marburg, Deutschland

    M. Wolf & K. Havemann

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  1. P. Drings
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Editor information

Editors and Affiliations

  1. Steinhölzle 16, D-89197, Westerstetten-Vorderdenkental, Deutschland

    W. Hartel

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© 1995 Springer-Verlag Berlin Heidelberg

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Drings, P. et al. (1995). Multimodale Therapieansätze bei der chirurgischen Therapie des Bronchialkarzinoms im Stadium III. In: Hartel, W. (eds) Qualitätssicherung durch Zusammenarbeit in der Chirurgie. Langenbecks Archiv für Chirurgie, vol 1995. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85235-0_37

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  • DOI: https://doi.org/10.1007/978-3-642-85235-0_37

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-60425-9

  • Online ISBN: 978-3-642-85235-0

  • eBook Packages: Springer Book Archive

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