Skip to main content

Epidermal Inclusion Cyst, Skin, Rat

  • Chapter
Integument and Mammary Glands

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

Epidermal inclusion cysts in rodents are intradermal or subcutaneous nodules, usually less than 0.5 cm in diameter. Grossly, they appear as a raised, smooth, round nodule in the skin. They may be attached to the skin and move with it, or be located under the skin and move independently (Figs.176 and 177). Upon excision, the nodule may consist of single or multiple cysts containing gray to white desiccated material (Weiss and Frese 1974). At necropsy, an epidermal inclusion cyst can be confused with neoplastic lesions of the skin. In the rat, epidermal inclusion cysts have been reported along the dorsal midline of the back (Burek 1978) and have been observed in the tail and hindleg at our laboratory, but most references fail to state where these cysts are located.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  • Burek JD (1978) Pathology of aging rats. CRC, West Palm Beach, pp 161–162 (Age-associated pathology of skin and subcutaneous tissues)

    Google Scholar 

  • Coleman GL, Barthold SW, Osbaldiston GW, Foster SJ, Jonas AM (1977) Pathological changes during aging in barrier-reared Fisher 344 male rats. J Gerontol 32: 258–278

    PubMed  CAS  Google Scholar 

  • Dodd DC, Port CD, Deslex P, Regnier B, Sanders P, Indacochea-Redmond N (1987) Two-year evaluation of misoprostol for carcinogenicity in CD Sprague-Dawley rats. Toxicol Pathol 15: 125–133

    Article  PubMed  CAS  Google Scholar 

  • Goodman DG, Ward JM, Squire RA, Chu KC, Lin-hart MS (1979) Neoplastic and non-neoplastic lesions in aging F344 rats. Toxicol Appl Pharmacol 48: 237–240

    Article  PubMed  CAS  Google Scholar 

  • Greaves P, Faccini JM (1984) Rat histopathology: a glossary for use in toxicity and carcinogenicity studies. Elsevier, Amsterdam, pp 1–3 (Integumentary system)

    Google Scholar 

  • Holland JM, Fry RIM (1982) Neoplasms of the integumentary system and harderian gland. In: Foster HL, Small JD, Fox JG (eds) The mouse in biomedical research–experimental biology and oncology, vol IV. Academic, New York, pp 516–522

    Google Scholar 

  • Inazu M, Sakaguchi T (1984) Morphologic characteristics of the skin of bald mutant rats. Lab Anin Sci 34 (6): 584–587

    CAS  Google Scholar 

  • Jones TC, Hunt RD (1983) Veterinary pathology. Lea and Febiger, Philadelpia, pp 1102–1118 (The skin and its appendages)

    Google Scholar 

  • Muller GH, Kirk RW (1976) Small animal dermatology, 2nd edn. Saunders, Philadelphia, pp 607–610

    Google Scholar 

  • Muller GH, Kirk RW (1983) Small animal dermatology, 3rd edn. Saunders, Philadelphia, pp 607–610

    Google Scholar 

  • Port CD, Dodd DC, Deslex P, Regnier B Sanders P, Indacochea-Redmond N (1987) Twenty-one-month evaluation of misoprostol for carcinogenicity in CD1 mice. Toxicol Pathol 15 (2): 134–142

    Article  PubMed  CAS  Google Scholar 

  • Robbins SL, Cotran RS (1979) Pathologic basis of disease, 2nd edn. Saunders, Philadelphia, p 1422

    Google Scholar 

  • Squire RA, Goodman DG, Valerio MG, Frederickson T, Strandberg JD, Levitt MH, Lingeman CH, Harshburger JC, Dawe CJ (1978) Tumors–integumentary system. In: Benirschke K, Garner FM, Jones TC (eds) Pathology of laboratory animals, vol II. Springer, Berlin Heidelberg New York, pp 1059–1062

    Google Scholar 

  • Weiss E, Frese K (1974) Tumors of the skin. In: WHO Bull 50: 79–100

    CAS  Google Scholar 

  • Yager JA, Scott DW (1985) Ectodermal neoplasms. In: Jubb KVF, Kennedy PC, Palmer N (eds) Pathology of domestic animals, vol 1. Academic, New York, pp 506–516

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Lake, S.G., Hart-Elcock, L., Mueller, R.E., Stuart, B.P. (1989). Epidermal Inclusion Cyst, Skin, Rat. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Integument and Mammary Glands. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83749-4_23

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-83749-4_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83751-7

  • Online ISBN: 978-3-642-83749-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics