Cerebral Hemodynamics During Nonpulsatile Cardiopulmonary Bypass

  • T. Lundar
Conference paper

Abstract

Cerebral damage during cardiac operations remains among the most serious and devastating complications of open heart surgery. A prospective study from Cleveland Clinic demonstrated a stroke risk of 5% during standard aortocoronary bypass operations: 2% of the patients were left with a substantial permanent cerebral deficit [5] and another 11% of the patients demonstrated clinical symptoms and signs of diffuse encephalopathy. Enormous numbers of cardiopulmonary bypass (CPB) procedures are now being done worldwide, but our knowledge of cerebral pathophysiological events during and after these operations remains scanty. Early experimental studies using electromagnetic carotid artery flowmetry indicated that the carotid flow fluctuated passively with the flow from the heart-lung machine during nonpulsatile CPB [4, 7].

Keywords

Cardiopulmonary Bypass Cerebral Perfusion Cerebral Perfusion Pressure Cerebral Autoregulation Cerebral Hemodynamic 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© Springer-Verlag Berlin Heidelberg 1989

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  • T. Lundar

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