Changes of the Bioelectrical Activity and Extracellular Micromilieu in the Central Nervous System During Variations of Local Oxygen Pressure

  • E.-J. Speckmann
  • D. Bingmann
  • A. Lehmenkühler
  • H. G. Lipinski
Chapter

Abstract

The present chapter gives a brief overview on our experimental observations concerning the effects of changes in oxygen pressure on neuronal functioning. In the experiments mentioned the oxygen pressure in nervous tissue was shifted to hypoxic and hyperoxic levels by various methods and techniques. In a variety of the described situations shifts of oxygen pressure caused simultaneous changes of carbon dioxide pressure and of H+ concentration which are due, e.g., to disturbances of microcirculation and/or to titration of bicarbonate. Therefore, a paragraph dealing with the actions of hypercapnia and acidosis is intercalated between the paragraphs devoted to effects of hypoxia and hyperoxia.

Keywords

Oxygen Pressure Hippocampal Slice Membrane Resistance Spinal Neuron Bioelectrical Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • E.-J. Speckmann
    • 1
  • D. Bingmann
    • 1
    • 2
  • A. Lehmenkühler
    • 1
  • H. G. Lipinski
    • 1
    • 3
  1. 1.Institut für PhysiologieUniversität MünsterMünsterGermany
  2. 2.Poliklinik für zahnärztliche Chirurgie der UniversitätMainzGermany
  3. 3.Neurologische Klinik der Technischen UniversitätMünchenGermany

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