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Current Therapeutic Concepts in Management of Carcinoma of the Anal Canal

  • J. Papillon
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 110)

Abstract

Radical surgery as initial treatment has been abandoned or questioned in most institutions in favor of a radio-chemotherapy approach, followed or not by surgery. The use of radiosensitizers such as 5-FU and mitomycin C during the first days of radiotherapy has been demonstrated as effective. Today the main problem consists in defining the most efficient protocol of radiotherapy able to give the highest chance of both tumor control and anal preservation.

Keywords

Anal Canal Booster Dose Anal Preservation Anal Area Intercurrent Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Papillon J (1982) Rectal and anal cancers. Conservative treatment by irradiation: an alternative to radical surgery. Springer, Berlin Heidelberg New YorkGoogle Scholar
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    Salmon RJ, Fenton J, Asselain B, Mathieu G, Girodet J, Durand JC, Decroix Y, Pilleron JP, Rousseau J (1984) Treatment of epidermoid anal canal cancer. Am J Surg 147: 43–48PubMedCrossRefGoogle Scholar
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    Eschwege F, Lasser P, Chavy A, Wibault P, Kac J, Rougier P, Bognel C (1985) Squamous cell carcinoma of the anal canal: treatment by external beam irradiation. Radiother Oncol 3:145–150PubMedCrossRefGoogle Scholar
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    Nigro MD, Vaitkevicius VK, Considine BJ (1974) Combined therapy for cancer of the anal canal. A preliminary report. Dis Colon Rectum 17: 354PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • J. Papillon
    • 1
  1. 1.Department of RadiotherapyCentre Léon BerardLyonFrance

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