Immunological Aspects of Thyroid Cancer

  • R. Hall
  • M. Ross
  • C. S. Teng
  • B. Rees Smith
Chapter
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 73)

Abstract

The role of immunological factors in the pathogenesis of thyroid cancer is complex and poorly understood. In this review the immunological associations of thyroid cancer will be considered in relation to three clinical entities, autoimmune thyroid disease, Graves’ disease, and thyroid lymphoma.

Keywords

Thyroid Cancer Papillary Carcinoma Autoimmune Thyroid Disease Immunological Aspect Subacute Thyroiditis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Brewer DB, Orr JW (1953) Struma reticulosa: A reconsideration of the undifferentiated tumours of the thyroid. J Pathol Bact 65: 193–208CrossRefGoogle Scholar
  2. 2.
    Brown RS, Jackson IMD, Pohl SL, Reichlin S (1978) Do thyroid-stimulating immunoglobulins cause non-toxic and toxic multinodular goitre? Lancet 1: 904–906PubMedCrossRefGoogle Scholar
  3. 3.
    Clague R, Mukhtar ED, Pyle GA, Nutt J, Clark F, Scott M, Evered D, Rees Smith B, Hall R (1976) Thyroid-stimulating immunoglobulins and control of thyroid function. J Clin Endocrinol Metab 43: 550–555PubMedCrossRefGoogle Scholar
  4. 4.
    DeGroot LJ, Haye K, Refetoff S, Van Herle AJ, Asteris GT, Rochman H (1977) Serum antigens and antibodies in the diagnosis of thyroid cancer. J Clin Endocrinol. Metab 45: 1220–1223PubMedCrossRefGoogle Scholar
  5. 5.
    Doniach I (1970) Aetiological consideration of thyroid carcinoma. In: Smithers D (ed) Tumours of the thyroid gland. Livingstone, Edinburgh London, pp 55–72Google Scholar
  6. 6.
    Fenzi G, Macchia E, Bartalena L, Mazzanti F, Baschieri L, DeGroot LJ (1978) Radio-receptor assay of TSH: its use to detect thyroid-stimulating immunoglobulins. J Endocrinol Invest 1: 17124Google Scholar
  7. 7.
    Goudie RB (1966) Thyroiditis and thyroid carcinoma, In: Appaix A (ed) Tumours of the thyroid gland. Karger, Basel New York, p 292Google Scholar
  8. 8.
    Hancock BW, Bing RF, Dirmikis SM, Munro DS, Neal FE (1971) Thyroid carcinoma and concurrent hyperthyroidism. A study of ten patients. Cancer 39: 298–302CrossRefGoogle Scholar
  9. 9.
    Kriss JP, Pleshakov V, Chien JR (1964) Isolation and identification of the long-acting thyroid stimulator and its relation to hyperthyroidism and circumscribed pretibial myxoedema. J Clin Endocrinol Metab 24: 1005–1028PubMedCrossRefGoogle Scholar
  10. 10.
    Mortensen JD, Bennett WA, Woolner LB (1955) Incidence of carcinoma in thyroid glands removed at 1000 consecutive routine necropsies. Sing Forum 5: 659–663Google Scholar
  11. 11.
    Olen E, Klinck GH (1966) Hyperthyroidism and thyroid cancer. Arch Pathol 81: 531–535PubMedGoogle Scholar
  12. 12.
    Rees Smith B, Hall R (1974) Thyroid-stimulating immunoglobulins in Graves’ disease. Lancet 2: 427–431Google Scholar
  13. 13.
    Ross WM, Teng CS, Davies TF, Scanlon MF, Evered DC, Rees Smith B, Hall R (to be published) Thyroid-stimulating antibodies, Graves’ disease and thyroid cancer. J Clin Endocrinol MetabGoogle Scholar
  14. 14.
    Snow MF, Davies T, Rees Smith B, Ross WM, Evans RGB, Teng CS, Hall R (to be published) Thyroid-stimulating antibodies and metastic thyroid carcinoma. J Clin Endocrinol MetabGoogle Scholar
  15. 15.
    Strakosch CR, Joyner D, Wall JR (1978) Thyroid-stimulating antibodies in patients with subacute thyroiditis. J Clin Endocrinol Metab 46: 345–348PubMedCrossRefGoogle Scholar
  16. 16.
    Tunbridge WMG, Evered DC, Hall R, Appleton D, Brewis M, Clark F, Grimley Evans J, Young E, Bird T, Smith PA (1977) The spectrum of thyroid disease in a community: the Whickham Survey. J Clin Endocrinol Metab 7: 481–493Google Scholar
  17. 17.
    Valenta L, Lemarchand-Berand T, Nemec J, Griessen M, Bednar J (1969) Metastic thyroid carcinoma provoking hyperthyroidism, with elevated circulating thyrostimulators. Am J Med 48: 72–76CrossRefGoogle Scholar
  18. 18.
    Williams ED, Doniach I, Bjarnason O, Michie W (1977) Thyroid cancer in an iodide rich area Cancer 39: 215–222Google Scholar
  19. 19.
    Woolner LB, McConahey WM, Beahrs OH (1959) Struma lymphomatosa ( Hashimoto’s thyroiditis) and related thyroidal disorders. J Clin Endocrinol Metab 19: 53–57PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1980

Authors and Affiliations

  • R. Hall
    • 1
  • M. Ross
    • 1
  • C. S. Teng
    • 1
  • B. Rees Smith
    • 1
  1. 1.Royal Victoria InfirmaryNewcastle-upon-TyneGB

Personalised recommendations